Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kevin G. McGarry"'
Autor:
Tyson P Winters, Jill A. Harvilchuck, Carol L. K. Sabourin, Erin E Lemmon, Kevin G. McGarry, Robert A. Moyer, Kevin E Schill
Publikováno v:
Toxicological Sciences. 174:124-132
Organophosphorus (OP) compounds, which include insecticides and chemical warfare nerve agents (CWNAs) such as sarin (GB) and VX, continue to be a global threat to both civilian and military populations. It is widely accepted that cholinesterase inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20005fe330f870fed616a8d85c05d07
https://doi.org/10.1093/toxsci/kfz250
https://doi.org/10.1093/toxsci/kfz250
Autor:
Kevin G. McGarry, Robert A. Moyer, Michael C. Babin, David T. Yeung, David A. Jett, Gennady E. Platoff
Publikováno v:
Pesticide Biochemistry and Physiology. 145:93-99
Phorate is a highly toxic agricultural pesticide currently in use throughout the world. Like many other organophosphorus (OP) pesticides, the primary mechanism of the acute toxicity of phorate is acetylcholinesterase (AChE) inhibition mediated by its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b81c79c74d43dd44d3278ed7b7ef096
https://doi.org/10.1016/j.pestbp.2018.01.009
https://doi.org/10.1016/j.pestbp.2018.01.009
Autor:
Yamin Fan, Hannah S. Shafaat, Alexi M Tallan, Kristyn M Johnson, Craig A. McElroy, Kevin G. McGarry, Jill A. Harvilchuck, Robert A. Moyer, Joeseph E Taris, Aniliese Deal, Tyson P Winters, David W. Wood, Erin E Lemmon, Christopher M. Hadad, Sean C. Marguet, Remy F. Lalisse
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 174(1)
Chemical warfare nerve agents (CWNAs) present a global threat to both military and civilian populations. The acute toxicity of CWNAs stems from their ability to effectively inhibit acetylcholinesterase (AChE). This inhibition can lead to uncontrolled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b704abfade11b647e5fcd8646058dd74
https://pubmed.ncbi.nlm.nih.gov/31879758
https://pubmed.ncbi.nlm.nih.gov/31879758
Publikováno v:
Chemical Warfare Agents ISBN: 9781498769235
Chemical Warfare Agents
Chemical Warfare Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e09d6c8f843f2f30b0c2c442e64eb18d
https://doi.org/10.1201/9781498769235-21
https://doi.org/10.1201/9781498769235-21
Autor:
Alexi M Tallan, Erin E Lemmon, Kristyn M Johnson, Christopher M. Hadad, Sean C. Marguet, Jill A. Harvilchuck, Yamin Fan, Joseph E. Taris, Remy F. Lalisse, Tyson P Winters, Aniliese Deal, Craig A. McElroy, Hannah S. Shafaat, David W. Wood, Kevin G. McGarry, Robert A. Moyer
Publikováno v:
Toxicological Sciences. 177:300-300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da5fa940b9a702c316d5f9bdecd4b47
https://doi.org/10.1093/toxsci/kfaa057
https://doi.org/10.1093/toxsci/kfaa057
Autor:
David A. Jett, Michael C. Babin, Kevin G. McGarry, Thomas H. Snider, Gennady E. Platoff, David T. Yeung
Publikováno v:
Fundamental toxicological sciences. 3(5)
The oral toxicity of phorate oxon (PHO), with emphasis on gender- and age-related effects, was characterized in the Sprague-Dawley rat. The oral LD50 (95% fiducial limits) for PHO in corn oil was 0.88 (0.79, 1.04) mg/kg in males and 0.55 (0.46, 0.63)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3f48e66c750bbce932cd83d19192a5
https://pubmed.ncbi.nlm.nih.gov/28856079
https://pubmed.ncbi.nlm.nih.gov/28856079
Autor:
Thomas H. Snider, Ryan A. Bartlett, Kevin G. McGarry, Robert A. Moyer, Matthew K. Brittain, Nicholas J. Machesky, David T. Yeung
Publikováno v:
Advances in Bioscience and Biotechnology. :1020-1023
Acetylcholine is an essential neurotransmitter found throughout the nervous system. Its action on postsynaptic receptors is regulated through hydrolysis by various carboxylesterases, especially cholinesterases (ChEs). The acute toxicity of organophos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33c46bc08b4060ea4e1a4467da1bbf83
https://doi.org/10.4236/abb.2013.412136
https://doi.org/10.4236/abb.2013.412136
Autor:
Michael C. Babin, Matthew K. Brittain, David T. Yeung, David A. Jett, Gennady E. Platoff, Kevin G. McGarry, Robert A. Moyer
Publikováno v:
International journal of toxicology. 35(3)
Purpose: Aldicarb and methomyl are carbamate pesticides commonly implicated in human poisonings. The primary toxic mechanism of action for carbamate poisoning is cholinesterase (ChE) inhibition. As such, it is logical to assume that the currently acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9267f06605943624324124c09b5d62dd
https://pubmed.ncbi.nlm.nih.gov/27102179
https://pubmed.ncbi.nlm.nih.gov/27102179
Publikováno v:
Molecular Cell. 20(4):613-622
Retention of the reading frame in ribosomal complexes after single-round translocation depends on the acylation state of the tRNA. When tRNA lacking a peptidyl group is translocated to the P site, the mRNA slips to allow re-pairing of the tRNA with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54967561c6e9af81822fa815f823b71c
Autor:
Kevin G, McGarry, Ryan A, Bartlett, Nicholas J, Machesky, Thomas H, Snider, Robert A, Moyer, David T, Yeung, Matthew K, Brittain
Publikováno v:
Advances in bioscience and biotechnology
Acetylcholine is an essential neurotransmitter found throughout the nervous system. Its action on postsynaptic receptors is regulated through hydrolysis by various carboxylesterases, especially cholinesterases (ChEs). The acute toxicity of organophos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53defb062613f8b34d75521d33124b00
https://pubmed.ncbi.nlm.nih.gov/24749000
https://pubmed.ncbi.nlm.nih.gov/24749000