Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kevin F. Staveley-O'Carrol"'
Autor:
Ming Yang, Xiaoqiang Qi, Nan Li, Jussuf T. Kaifi, Shiyou Chen, Andrew A. Wheeler, Eric T. Kimchi, Aaron C. Ericsson, R. Scott Rector, Kevin F. Staveley-O’Carroll, Guangfu Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The interplay between western diet and gut microbiota drives the development of non-alcoholic fatty liver disease and its progression to non-alcoholic steatohepatitis. However, the specific microbial and metabolic mediators contributing to n
Externí odkaz:
https://doaj.org/article/b4b77dd13ef64968b1d1ab140e504033
Autor:
Kanve N. Suvilesh, Yulia I. Nussbaum, Vijay Radhakrishnan, Yariswamy Manjunath, Diego M. Avella, Kevin F. Staveley-O’Carroll, Eric T. Kimchi, Aadel A. Chaudhuri, Chi-Ren Shyu, Guangfu Li, Klaus Pantel, Wesley C. Warren, Jonathan B. Mitchem, Jussuf T. Kaifi
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-8 (2022)
Abstract Background Circulating tumor cells (CTCs) are liquid biopsies that represent micrometastatic disease and may offer unique insights into future recurrences in non-small cell lung cancer (NSCLC). Due to CTC rarity and limited stability, no sta
Externí odkaz:
https://doaj.org/article/a2df1dda5fd74b0dbf8798da022a3a42
Autor:
Mouadh Barbirou, Amanda Miller, Yariswamy Manjunath, Arturo B. Ramirez, Nolan G. Ericson, Kevin F. Staveley-O’Carroll, Jonathan B. Mitchem, Wesley C. Warren, Aadel A. Chaudhuri, Yi Huang, Guangfu Li, Peter J. Tonellato, Jussuf T. Kaifi
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 2, Pp 750-763 (2022)
Non-small-cell lung cancer (NSCLC) accounts for most cancer-related deaths worldwide. Liquid biopsy by a blood draw to detect circulating tumor cells (CTCs) is a tool for molecular profiling of cancer using single-cell and next-generation sequencing
Externí odkaz:
https://doaj.org/article/330aa8b920e541a482532e69ead1d49b
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1391 (2023)
Liver fibrosis accompanies the development of various chronic liver diseases and promotes their progression. It is characterized by the abnormal accumulation of extracellular matrix proteins (ECM) and impaired ECM degradation. Activated hepatic stell
Externí odkaz:
https://doaj.org/article/1ef0cf908b594be59c443cff8e1020fd
Autor:
Xiaoqiang Qi, Yajun Liu, Samira Hussein, Grace Choi, Eric T. Kimchi, Kevin F. Staveley-O’Carroll, Guangfu Li
Publikováno v:
Cells, Vol 11, Iss 22, p 3684 (2022)
Both preclinical and clinical studies have demonstrated that the modulation of gut microbiota could be a promising strategy for enhancing antitumor immune responses and reducing resistance to immunotherapy in cancer. Various mechanisms, including act
Externí odkaz:
https://doaj.org/article/3e929575f11245f8a8b0057f0f950aaa
Autor:
Ming Yang, Olamide Tosin Olaoba, Chunye Zhang, Eric T. Kimchi, Kevin F. Staveley-O’Carroll, Guangfu Li
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1630 (2022)
With an understanding of immunity in the tumor microenvironment, immunotherapy turns out to be a powerful tool in the clinic to treat many cancers. The strategies applied in cancer immunotherapy mainly include blockade of immune checkpoints, adoptive
Externí odkaz:
https://doaj.org/article/ae620e8aa8114e29b6b94b94f3c55d70
Autor:
Ming Yang, Lea Khoukaz, Xiaoqiang Qi, Eric T. Kimchi, Kevin F. Staveley-O’Carroll, Guangfu Li
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1893 (2021)
Nonalcoholic fatty liver disease (NAFLD) with pathogenesis ranging from nonalcoholic fatty liver (NAFL) to the advanced form of nonalcoholic steatohepatitis (NASH) affects about 25% of the global population. NAFLD is a chronic liver disease associate
Externí odkaz:
https://doaj.org/article/d2b0ac6446854046b51fdb714a475df8
Autor:
Dai Liu, Guangfu Li, Diego M. Avella, Eric T. Kimchi, Jussuf T. Kaifi, Mark P. Rubinstein, E. Ramsay Camp, Don C. Rockey, Todd D. Schell, Kevin F. Staveley-O'Carroll
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
Successful development of immunotherapeutic strategies for hepatocellular cancer (HCC) has been impeded by limited understanding of tumor-induced profound tolerance and lack of a clinically faithful HCC model. Recently, we developed a novel model tha
Externí odkaz:
https://doaj.org/article/0516ffea6c534568ae9148e8f9655751
Autor:
Hephzibah Rani S. Tagaram, Dhimant Desai, Guangfu Li, Dai Liu, C. Bart Rountree, Kavitha Gowda, Arthur Berg, Shantu Amin, Kevin F. Staveley-O’Carroll, Eric T. Kimchi
Publikováno v:
Pharmaceuticals, Vol 9, Iss 2, p 18 (2016)
Hepatocellular carcinoma (HCC) is the third most deadly cancer in the world. New treatment strategies are desperately needed due to limited standard therapies. Activation of the Erk, Akt, and STAT3pathways is implicated in the prognosis of HCC. The S
Externí odkaz:
https://doaj.org/article/78fa283f47714a8fbf9ad85d01c6f709
Autor:
Andrew A. Wheeler, Christopher A. Foote, Jaume Padilla, Arthur L. Rawlings, Robert M. Restaino, Jorge A. Castorena-Gonzalez, Luis A. Martinez-Lemus, Kevin F. Staveley-O’Carrol, Mariana Morales-Quinones, Thaysa Ghiarone Araujo Silva
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9aabf1fab0785b78cb256c6ef97c6a
https://doi.org/10.1096/fasebj.2019.33.1_supplement.685.7
https://doi.org/10.1096/fasebj.2019.33.1_supplement.685.7