Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Kevin F. O'Connell"'
Autor:
Jyoti Iyer, Lindsey K Gentry, Mary Bergwell, Amy Smith, Sarah Guagliardo, Peter A Kropp, Prabhu Sankaralingam, Yan Liu, Eric Spooner, Bruce Bowerman, Kevin F O'Connell
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1009799 (2022)
Centrioles are submicron-scale, barrel-shaped organelles typically found in pairs, and play important roles in ciliogenesis and bipolar spindle assembly. In general, successful execution of centriole-dependent processes is highly reliant on the abili
Externí odkaz:
https://doaj.org/article/5bcfdfa314f642979898e75a381717f3
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 3, Pp 709-720 (2016)
Centrioles play critical roles in the organization of microtubule-based structures, from the mitotic spindle to cilia and flagella. In order to properly execute their various functions, centrioles are subjected to stringent copy number control. Centr
Externí odkaz:
https://doaj.org/article/5088b519b7224ed9ae426db6efd58608
Autor:
Kevin F. O’Connell
Publikováno v:
Curr Biol
During mitosis in animal cells, the centrosome acts as a microtubule organizing center (MTOC) to assemble the mitotic spindle. MTOC function at the centrosome is driven by proteins within the pericentriolar material (PCM), however the molecular compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e093a2ba2248a6a2fb065b981b3bed6
https://doi.org/10.1016/j.cub.2021.03.101
https://doi.org/10.1016/j.cub.2021.03.101
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006543 (2017)
In humans perturbations of centriole number are associated with tumorigenesis and microcephaly, therefore appropriate regulation of centriole duplication is critical. The C. elegans homolog of Plk4, ZYG-1, is required for centriole duplication, but o
Externí odkaz:
https://doaj.org/article/ee503e27802247b9b55c886c3462d397
Autor:
Kevin F, O'Connell
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2468
One of the key attributes that has contributed to the popularity of Caenorhabditis elegans as a model system is its ability to survive freezing. By preserving stocks at ultralow temperature, researchers have been able to generate an unlimited number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50c45c43d1ded77ea8d13b97fce6be71
https://pubmed.ncbi.nlm.nih.gov/35320559
https://pubmed.ncbi.nlm.nih.gov/35320559
Publikováno v:
Cells, Vol 7, Iss 8, p 101 (2018)
Theodor Boveri is considered as the “father” of centrosome biology. Boveri’s fundamental findings have laid the groundwork for decades of research on centrosomes. Here, we briefly review his early work on centrosomes and his first description o
Externí odkaz:
https://doaj.org/article/11426e3c4fac4200a8bb227b2aa84aa8
Autor:
Amy Smith, Sarah Guargliardo, Bruce Bowerman, Prabhu Sankaralingam, Kevin F. O’Connell, Eric Spooner, Jyoti Iyer, Peter A. Kropp, Mary Bergwell, Yan Liu, Lindsey Gentry
Publikováno v:
PLoS genetics. 18(4)
Centrioles are submicron-scale, barrel-shaped organelles typically found in pairs, and play important roles in ciliogenesis and bipolar spindle assembly. In general, successful execution of centriole-dependent processes is highly reliant on the abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64866276d3045e4d9ca60fd7913a71ce
https://pubmed.ncbi.nlm.nih.gov/35377871
https://pubmed.ncbi.nlm.nih.gov/35377871
Autor:
Bruce Bowerman, Gunar Fabig, Nicole DeVaul, Kevin F. O’Connell, Thomas Mueller‐Reichert, Sarah Guagliardo
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c49824d0e158b140983196102cca415d
https://doi.org/10.1096/fasebj.2019.33.1_supplement.610.21
https://doi.org/10.1096/fasebj.2019.33.1_supplement.610.21
Publikováno v:
Cells, Vol 7, Iss 8, p 101 (2018)
Cells
Cells
Theodor Boveri is considered as the “father” of centrosome biology. Boveri’s fundamental findings have laid the groundwork for decades of research on centrosomes. Here, we briefly review his early work on centrosomes and his first description o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c913ae7ff4e71988588f65c73dccd0
http://www.mdpi.com/2073-4409/7/8/101
http://www.mdpi.com/2073-4409/7/8/101
Publikováno v:
Dev Biol
CDK11, a member of the cyclin-dependent kinase family, has been implicated in a diverse array of functions including transcription, RNA processing, sister chromatid cohesion, spindle assembly, centriole duplication and apoptosis. Despite its involvem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fea01d8132df5f73384d162b1ffe90f
https://pubmed.ncbi.nlm.nih.gov/29886128
https://pubmed.ncbi.nlm.nih.gov/29886128