Výsledky vyhledávání - "Kevin E, Schill"

Characterization of Cholinesterases From Multiple Large Animal Species for Medical Countermeasure Development Against Chemical Warfare Nerve Agents

Autor: Tyson P Winters, Jill A. Harvilchuck, Carol L. K. Sabourin, Erin E Lemmon, Kevin G. McGarry, Robert A. Moyer, Kevin E Schill

Publikováno v: Toxicological Sciences. 174:124-132

Organophosphorus (OP) compounds, which include insecticides and chemical warfare nerve agents (CWNAs) such as sarin (GB) and VX, continue to be a global threat to both civilian and military populations. It is widely accepted that cholinesterase inhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20005fe330f870fed616a8d85c05d07
https://doi.org/10.1093/toxsci/kfz250

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Akademický článek

Prednisolone attenuates improvement of cardiac and skeletal contractile function and histopathology by lisinopril and spironolactone in the mdx mouse model of Duchenne muscular dystrophy.

Autor: Paul M L Janssen, Jason D Murray, Kevin E Schill, Neha Rastogi, Eric J Schultz, Tam Tran, Subha V Raman, Jill A Rafael-Fortney

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e88360 (2014)

Duchenne muscular dystrophy (DMD) is an inherited disease that causes striated muscle weakness. Recently, we showed therapeutic effects of the combination of lisinopril (L), an angiotensin converting enzyme (ACE) inhibitor, and spironolactone (S), an

Externí odkaz: https://doaj.org/article/ab56521f9d8d4acfa90e1e22a0eee762

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The presence of symptoms of testosterone deficiency in the exercise-hypogonadal male condition and the role of nutrition

Autor: Brian C. Focht, Carl M. Maresh, Catherine Saenz, Kevin E. Schill, Jeff S. Volek, David R. Hooper, William J. Kraemer

Publikováno v: European Journal of Applied Physiology. 117:1349-1357

High volumes of aerobic exercise have been associated with reduced testosterone (T), known as the exercise-hypogonadal male condition (EHMC). Although the presence of low T has been identified, few studies have assessed the presence of androgen-defic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0d95ab38c074e0bfca2970e164e966
https://doi.org/10.1007/s00421-017-3623-z

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Muscle damage, metabolism, and oxidative stress in mdx mice: Impact of aerobic running

Autor: Frederick A. Villamena, Alex. R. Altenberger, Kevin E. Schill, Steven T. Devor, Jill A. Rafael-Fortney, Muthu Periasamy, Jeovanna Lowe

Publikováno v: Muscle & Nerve. 54:110-117

Introduction: We tested how a treadmill exercise program influences oxygen consumption, oxidative stress, and exercise capacity in the mdx mouse, a model of Duchenne muscular dystrophy. Methods: At age 4 weeks mdx mice were subjected to 4 weeks of tw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9643e96faea477eb0c5a529f2b9a03fb
https://doi.org/10.1002/mus.25015

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Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet

Autor: Teryn N. Sapper, Eunice Mah, Philip R. Rohrer, Swetha Rudraiah, Chureeporn Chitchumroonchokchai, Meredith V. Moller, Kevin E. Schill, Jinhui Li, Richard S. Bruno, Joshua D. McDonald, José E. Manautou

Publikováno v: Molecular Nutrition & Food Research. 60:858-870

Scope Green tea extract (GTE) reduces liver steatosis and inflammation during nonalcoholic steatohepatitis (NASH). We hypothesized GTE would mitigate NASH in a nuclear factor erythroid-2-related-factor-2 (Nrf2)-dependent manner in a high fat (HF) ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3696dce851c8b04b36833b86e63cb630
https://doi.org/10.1002/mnfr.201500814

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α-Tocopherol bioavailability is lower in adults with metabolic syndrome regardless of dairy fat co-ingestion: a randomized, double-blind, crossover trial

Autor: Teryn N. Sapper, Steven K. Clinton, Mark L. Failla, Richard S. Bruno, Maret G. Traber, Chureeporn Chitchumroonchokchai, Kevin E. Schill, Eunice Mah, Gerd Bobe

Publikováno v: The American Journal of Clinical Nutrition. 102:1070-1080

Background: Increasing dietary fat intake is expected to improve α-tocopherol bioavailability, which could be beneficial for improving α-tocopherol status, especially in cohorts at high cardiometabolic risk who fail to meet dietary α-tocopherol re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c3bd90507d7f193da2324aad07b888
https://doi.org/10.3945/ajcn.115.118570

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Cardiomyopathy in the dystrophin/utrophin-deficient mouse model of severe muscular dystrophy is characterized by dysregulation of matrix metalloproteinases

Autor: Kara E Zang, Nikita T. Patel, Jill A. Rafael-Fortney, Dawn A. Delfín, Subha V. Raman, Paul M.L. Janssen, Kevin E. Schill

Publikováno v: Neuromuscular Disorders. 22:1006-1014

Cardiomyopathy is a significant component in Duchenne muscular dystrophy. Although mdx mice are deficient in dystrophin, they only develop mild indicators of cardiomyopathy before 1year-of-age, making therapeutic investigations using this model lengt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da587d5019ee5d0168557842a03a6638
https://doi.org/10.1016/j.nmd.2012.05.002

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Sustaining Cardiac Claudin-5 Levels Prevents Functional Hallmarks of Cardiomyopathy in a Muscular Dystrophy Mouse Model

Autor: Kevin E. Schill, Kara E Zang, Benjamin D. Canan, Tessily A. Mays, Paul M.L. Janssen, Jill A. Rafael-Fortney, Dawn A. Delfín, Ying Xu, Jamie A Barnum

Publikováno v: Molecular Therapy. 20:1378-1383

Identification of new molecular targets in heart failure could ultimately have a substantial positive impact on both the health and financial aspects of treating the large heart failure population. We originally identified reduced levels of the cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16324f47c882c9a1fcda8b56159c847
https://doi.org/10.1038/mt.2012.81

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Muscle damage, metabolism, and oxidative stress in mdx mice: Impact of aerobic running

Autor: Kevin E, Schill, Alex R, Altenberger, Jeovanna, Lowe, Muthu, Periasamy, Frederick A, Villamena, JIll A, Rafael-Fortney, Steven T, Devor

Publikováno v: Musclenerve. 54(1)

We tested how a treadmill exercise program influences oxygen consumption, oxidative stress, and exercise capacity in the mdx mouse, a model of Duchenne muscular dystrophy.At age 4 weeks mdx mice were subjected to 4 weeks of twice-weekly treadmill exe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::279ce6812a86e99ac133068ce321ac87
https://pubmed.ncbi.nlm.nih.gov/26659868

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