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Thiol activation of a model O2-aryl diazeniumdiolate prodrug in phospholipid vesicle media

Autor: Kevin Dove, Mohamad N. Zanbrakji, Marit Peterson, Keith M. Davies, Stacy E. Price, Bach T. Dinh

Publikováno v: Nitric oxide : biology and chemistry. 19(4)

Thiolysis of the model diazeniumdiolate prodrug, O2-(2,4-dinitrophenyl) 1-(N,N-diethylamino)diazen-1-ium-1,2-diolate (DNP-DEA/NO, 1), by glutathione (GSH), cysteine (CYSH) and 1-heptanethiol (heptylmercaptan, HM) has been examined in anionic (DOPG),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec74a95a235e344c34a0796754ce8dc
https://pubmed.ncbi.nlm.nih.gov/18675930

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Effect of hydrophobic structure on the catalysis of nitric oxide release from zwitterionic diazeniumdiolates in surfactant and liposome media

Autor: Keith M. Davies, Joseph A. Hrabie, Dilara Jappar, Kevin Dove, Bach T. Dinh

Publikováno v: Nitric oxide : biology and chemistry. 13(3)

The effect of phospholipid liposomes and surfactant micelles on the rate of nitric oxide release from zwitterionic diazeniumdiolates, R1R2N[N(O)NO]-, with significant hydrophobic structure, has been explored. The acid-catalyzed dissociation of NO has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61283c7e16da4c986bf2c7a3b7e2dda3
https://pubmed.ncbi.nlm.nih.gov/16122951

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