Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kevin Dorgans"'
Autor:
Ludovic Spaeth, Jyotika Bahuguna, Theo Gagneux, Kevin Dorgans, Izumi Sugihara, Bernard Poulain, Demian Battaglia, Philippe Isope
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The variability in synaptic connectivity observed at the cerebellar granule cell - Purkinje cell connection in mice accounts for motor behavior traits at the individual level, suggesting that cerebellar networks encode internal models underlying indi
Externí odkaz:
https://doaj.org/article/d4a5c485789c4484934954b568186b6d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Adeno-associated viral (AAV) vectors, used as vehicles for gene transfer into the brain, are a versatile and powerful tool of modern neuroscience that allow identifying specific neuronal populations, monitoring and modulating their activity. For cons
Externí odkaz:
https://doaj.org/article/929b174d658a488aba05af84669ab049
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Voltage imaging with cellular resolution in mammalian brain slices is still a challenging task. Here, we describe and validate a method for delivery of the voltage-sensitive dye ANNINE-6plus (A6+) into tissue for voltage imaging that results in highe
Externí odkaz:
https://doaj.org/article/df6159724dc04e338ba9c44d3f81ec94
Autor:
Isabelle Straub, Laurens Witter, Abdelmoneim Eshra, Miriam Hoidis, Niklas Byczkowicz, Sebastian Maas, Igor Delvendahl, Kevin Dorgans, Elise Savier, Ingo Bechmann, Martin Krueger, Philippe Isope, Stefan Hallermann
Publikováno v:
eLife, Vol 9 (2020)
Cerebellar granule cells (GCs) make up the majority of all neurons in the vertebrate brain, but heterogeneities among GCs and potential functional consequences are poorly understood. Here, we identified unexpected gradients in the biophysical propert
Externí odkaz:
https://doaj.org/article/c7722a47401c436587eace6d5e2e9dbd
Autor:
Kevin Dorgans, Julie Salvi, Federica Bertaso, Ludivine Bernard, Philippe Lory, Frederic Doussau, Alexandre Mezghrani
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 110-123 (2017)
Episodic Ataxia type 2 (EA2) is an autosomal dominant neuronal disorder linked to mutations in the Cav2.1 subunit of P/Q-type calcium channels. In vitro studies have established that EA2 mutations induce loss of channel activity and that EA2 mutants
Externí odkaz:
https://doaj.org/article/95d27118ac764f4fa5133ffc2df69352
Autor:
Kevin Dorgans, Valérie Demais, Yannick Bailly, Bernard Poulain, Philippe Isope, Frédéric Doussau
Publikováno v:
eLife, Vol 8 (2019)
Information processing by cerebellar molecular layer interneurons (MLIs) plays a crucial role in motor behavior. MLI recruitment is tightly controlled by the profile of short-term plasticity (STP) at granule cell (GC)-MLI synapses. While GCs are the
Externí odkaz:
https://doaj.org/article/925339f81df0457cb06e9b172e515c7b
Autor:
Frédéric Doussau, Hartmut Schmidt, Kevin Dorgans, Antoine M Valera, Bernard Poulain, Philippe Isope
Publikováno v:
eLife, Vol 6 (2017)
The segregation of the readily releasable pool of synaptic vesicles (RRP) in sub-pools that are differentially poised for exocytosis shapes short-term plasticity. However, the frequency-dependent mobilization of these sub-pools is poorly understood.
Externí odkaz:
https://doaj.org/article/ae2db80c8d7a4ec4870543bff33b7f83
Publikováno v:
Neuromethods ISBN: 9781071620250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9503dde9dce167f0e07e2a0c1176e8b
https://doi.org/10.1007/978-1-0716-2026-7_8
https://doi.org/10.1007/978-1-0716-2026-7_8
Publikováno v:
Neuromethods ISBN: 9781071620250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff01aac9a57ce70e486e770620b76db5
https://doi.org/10.1007/978-1-0716-2026-7_9
https://doi.org/10.1007/978-1-0716-2026-7_9
Autor:
Kevin Dorgans, Bernard Poulain, Theo Gagneux, Izumi Sugihara, Ludovic Spaeth, Philippe Isope, Demian Battaglia, Jyotika Bahuguna
From planification to execution, cerebellar microcircuits encode different features of skilled movements. However, it is unknown whether cerebellar synaptic connectivity maps encode movement features in a motor context specific manner. Here we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502fd02ae138f210dd9585c4a5097c2a
https://hal.science/hal-03437590/document
https://hal.science/hal-03437590/document