Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kevin Despain"'
Autor:
Kevin DeSpain, Charles R. Rosenfeld, Ryan Huebinger, Xiaofu Wang, Jayson W. Jay, Ravi S. Radhakrishnan, Steven E. Wolf, Juquan Song
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Severe burns result in cardiovascular dysfunction, but responses in the peripheral vasculature are unclear. We hypothesize that severe burns disturb arterial contractility through acute changes in adrenergic and cholinergic receptor function
Externí odkaz:
https://doaj.org/article/68cdfd1fdca14e978a1fbb0f617ea222
Autor:
Kevin Despain, Juquan Song, Steven E. Wolf, Brett A. Carlson, Lisa A. Baer, Charles E. Wade, Melody R. Saeman, Ming Mei Liu
Publikováno v:
Journal of Surgical Research. 198:19-26
Muscle loss is a sequela of severe burn and critical illness with bed rest contributing significantly to atrophy. We hypothesize that exercise will mitigate muscle loss after burn with bed rest.Male rats were assigned to sham ambulatory (S/A), burn a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76116ec3084bbfad2a3f8e73eb35017
https://doi.org/10.1016/j.jss.2015.05.038
https://doi.org/10.1016/j.jss.2015.05.038
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 302:R59-R67
The intact ovine uterine vascular bed (UVB) is sensitive to α-agonists and refractory to angiotensin II (ANG II) during pregnancy; the converse occurs in the systemic circulation. The mechanism(s) responsible for these differences in uterine sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ff76ff88f15c8e81c6fb243328613e
https://doi.org/10.1152/ajpregu.00424.2011
https://doi.org/10.1152/ajpregu.00424.2011
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 97:138-147
During pregnancy, uteroplacental responses to norepinephrine (NE) exceed systemic responses. In contrast, uteroplacental responses to angiotensin II (ANG II) are less than systemic. The explanation for these differences in uteroplacental sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab126ba57c73130fdff8139e3eae9b4
https://doi.org/10.1210/jc.2011-1818
https://doi.org/10.1210/jc.2011-1818
Publikováno v:
Reproductive Sciences. 15:651-660
Large conductance K( +) channels (BK(Ca)) are expressed in uterine artery (UA) smooth muscle from nonpregnant and pregnant sheep and contribute to the regulation of basal vascular tone and responses to estrogen and vasoconstrictors. To determine if B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bee9b8577136f46086799e870b42b60
https://doi.org/10.1177/1933719108319160
https://doi.org/10.1177/1933719108319160
Publikováno v:
The Journal of surgical research. 202(2)
Background Severe burn causes muscle mass loss and atrophy. The balance between muscle cell death and growth maintains tissue homeostasis. We hypothesize that preexisting cellular structural defects will exacerbate skeletal muscle mass loss after bur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5ad6e0963ac76cec3fd14e2c7d353c
https://pubmed.ncbi.nlm.nih.gov/27229112
https://pubmed.ncbi.nlm.nih.gov/27229112
Publikováno v:
Pediatric Research. 58:58-65
Mean arterial pressure (MAP) increases after birth, however, the mechanisms remain unclear. Systemic angiotensin II (ANG II) infusions increase MAP in newborn sheep, but the direct effects of ANG II on peripheral vascular resistance (PVR) are minimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d8b8f555dc1dee8d6a32dfed90892a
https://doi.org/10.1203/01.pdr.0000163395.07153.90
https://doi.org/10.1203/01.pdr.0000163395.07153.90
Publikováno v:
Pediatric Research. 52:333-341
Angiotensin II (ANG II) increases blood pressure (MAP) via specific ANG II receptors (AT) and is considered important in regulating MAP after birth. In adult animals, AT1 receptors predominate in vascular smooth muscle (VSM) and mediate vasoconstrict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da4081e6b682d3464b8503ca0bc94af
https://doi.org/10.1203/00006450-200209000-00005
https://doi.org/10.1203/00006450-200209000-00005
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 296(6)
Regulation of uteroplacental blood flow (UPBF) during pregnancy remains unclear. Large conductance, Ca2+-activated K+ channels (BKCa), consisting of α- and regulatory β-subunits, are expressed in uterine vascular smooth muscle (UVSM) and contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b409976744f7a2daba5ad90e4768b011
https://pubmed.ncbi.nlm.nih.gov/19470517
https://pubmed.ncbi.nlm.nih.gov/19470517
Arginine vasopressin (AVP) is an important regulator of cardiovascular homeostasis in the fetus, but its role after birth is unclear. Although infused AVP increases mean arterial pressure (MAP) during the 1st mo after birth, pressor responses are unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b2ce43a35b131d09b9102e31e4d4ec
https://europepmc.org/articles/PMC2536728/
https://europepmc.org/articles/PMC2536728/
