Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kevin Danastas"'
Autor:
Kevin Danastas, Gerry Guo, Jessica Merjane, Nathan Hong, Ava Larsen, Monica Miranda-Saksena, Anthony L. Cunningham
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Herpes simplex virus-1 (HSV-1) has evolved mechanisms to evade the host immune system and limit the antiviral effects induced by interferon (IFN) produced by local epithelial and immune cells. In this study, we determined the effects of type
Externí odkaz:
https://doaj.org/article/f3457912712941b1824858ab60759adc
Autor:
Kevin Danastas, Ava Larsen, Sophie Jobson, Gerry Guo, Anthony L Cunningham, Monica Miranda-Saksena
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010264 (2022)
Herpes simplex virus type 1 (HSV-1) has evolved mechanisms to exploit the host cytoskeleton during entry, replication and exit from cells. In this study, we determined the role of actin and the molecular motor proteins, myosin II and myosin V, in the
Externí odkaz:
https://doaj.org/article/c1798742554648c2a1895eca11a0386a
Autor:
Kirstie M Bertram, Naomi R Truong, Jacinta B Smith, Min Kim, Kerrie J Sandgren, Konrad L Feng, Jason J Herbert, Hafsa Rana, Kevin Danastas, Monica Miranda-Saksena, Jake W Rhodes, Ellis Patrick, Ralph C Cohen, Jake Lim, Steven L Merten, Andrew N Harman, Anthony L Cunningham
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009536 (2021)
Skin mononuclear phagocytes (MNPs) provide the first interactions of invading viruses with the immune system. In addition to Langerhans cells (LCs), we recently described a second epidermal MNP population, Epi-cDC2s, in human anogenital epidermis tha
Externí odkaz:
https://doaj.org/article/16caffee82494e02a8f58ec3e503dd35
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5150 (2020)
The interferon (IFN) system is one of the first lines of defense activated against invading viral pathogens. Upon secretion, IFNs activate a signaling cascade resulting in the production of several interferon stimulated genes (ISGs), which work to li
Externí odkaz:
https://doaj.org/article/442bcf3e4b5b49058abd3f1730d44838
Autor:
Monica Miranda-Saksena, Ellis Patrick, Jake W. Rhodes, Kevin Danastas, Kirstie M. Bertram, Kerrie J Sandgren, Hafsa Rana, Naomi R. Truong, Min Kim, Steven Merten, Konrad L. Feng, Andrew N. Harman, Jake Lim, Ralph C. Cohen, Jason J. Herbert, Anthony L. Cunningham, Jacinta B. Smith
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009536 (2021)
PLoS Pathogens
PLoS Pathogens
Skin mononuclear phagocytes (MNPs) provide the first interactions of invading viruses with the immune system. In addition to Langerhans cells (LCs), we recently described a second epidermal MNP population, Epi-cDC2s, in human anogenital epidermis tha
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2060
Understanding how herpes simplex virus-1 (HSV-1) interacts with different parts of the neuron is fundamental in understanding the mechanisms behind HSV-1 transport during primary and recurrent infections. In this chapter, we describe a unique neurona
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998135
Understanding how herpes simplex virus-1 (HSV-1) interacts with different parts of the neuron is fundamental in understanding the mechanisms behind HSV-1 transport during primary and recurrent infections. In this chapter, we describe a unique neurona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fda7a95dcbec30645d8d65f6bd20038
https://doi.org/10.1007/978-1-4939-9814-2_25
https://doi.org/10.1007/978-1-4939-9814-2_25
Autor:
Samson N. Dowland, Kevin Danastas, Camilla M. Whittington, Laura A. Lindsay, Valery Combes, Christopher R. Murphy
© The Author(s) 2018. The angiogenic factor vascular endothelial growth factor-A (VEGFA) plays a critical role during early pregnancy in many species including the rat, and any alterations in VEGFA levels can severely impact blastocyst implantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46894dcb84072bce38a35812d9b091a
https://hdl.handle.net/10453/130772
https://hdl.handle.net/10453/130772
Autor:
Georges E. Grau, Christopher R. Murphy, Kevin Danastas, Michael B. Thompson, Camilla M. Whittington
Publikováno v:
Journal of Comparative Physiology B. 187:353-360
Vascular endothelial growth factor A is a major mediator of angiogenesis, a critically important process in vertebrate growth and development as well as pregnancy. Here we report for the first time the expression of a rare and unusually potent splice
Autor:
Alison J. Hey-Cunningham, Emily J. Miller, Kevin Danastas, Christopher R. Murphy, Laura A. Lindsay
Publikováno v:
Reproduction, fertility, and development. 30(4)
Angiogenesis is a critical step in the development of ectopic lesions during endometriosis. Although total vascular endothelial growth factor (VEGF) A is elevated in the peritoneal fluid of women with endometriosis, there are contradictory reports on