Výsledky vyhledávání - "Kevin D. Staton"

Pharmacokinetic Assessment of

Autor: Milan, Grkovski, Reema, Goel, Simone, Krebs, Kevin D, Staton, James J, Harding, Ingo K, Mellinghoff, John L, Humm, Mark P S, Dunphy

Publikováno v: J Nucl Med

(18)F-(2S,4R)-4-fluoroglutamine ((18)F-FGln) is an investigational PET radiotracer for imaging tumor glutamine flux and metabolism. The aim of this study was to investigate its pharmacokinetic properties in patients with cancer. Methods: Fifty lesion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9236b5286ab5fb5f2d6683be6f5a4abf
https://pubmed.ncbi.nlm.nih.gov/31601700

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Biodistribution and Dosimetry of

Autor: Neeta, Pandit-Taskar, Pat, Zanzonico, Kevin D, Staton, Jorge A, Carrasquillo, Diane, Reidy-Lagunes, Serge, Lyashchenko, Eva, Burnazi, Hanwen, Zhang, Jason S, Lewis, Ronald, Blasberg, Steven M, Larson, Wolfgang A, Weber, Shakeel, Modak

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 59(1)

123I-meta-iodobenzylguanidine (123I-MIBG) imaging is currently a mainstay in the evaluation of many neuroendocrine tumors, especially neuroblastoma. 123I-MIBG imaging has several limitations that can be overcome by the use of a PET agent. 18F-meta-fl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5c926b7e94e7e8822852463dea0e91a8
https://pubmed.ncbi.nlm.nih.gov/28705916

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Assessment of Nuclear Nanomorphology Marker to Improve the Detection of Malignancy From Bile Duct Biopsy Specimens

Autor: Rajan K. Bista, Douglas J. Hartman, Kevin D. Staton, Sumera Rizvi, Yang Liu, Adam Slivka, Shikhar Uttam, Alyssa M. Krasinskas, Randall E. Brand

Publikováno v: American Journal of Clinical Pathology. 141:884-891

Objectives: The accurate diagnosis of malignancy from small bile duct biopsy specimens is often challenging. This proof-of-concept study assessed the feasibility of a novel optical technology, spatial-domain low-coherence quantitative phase microscop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e62cc604596ccfe9b1c3841c1be633
https://doi.org/10.1309/ajcpxqd0nsjnk0cx

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Nuclear Nano-architecture Markers of Gastric Cardia and Upper Squamous Esophagus Detect Esophageal Cancer 'Field Effect'

Autor: Yang Liu, Kenneth E. Fasanella, Shikhar Uttam, Kevin D. Staton, Chengquan Zhao, Kevin McGrath, Randall E. Brand, Sumera Rizvi, Rajan K. Bista, Antonia R. Sepulveda

Publikováno v: Journal of Cancer

Background: Barrett's esophagus (BE) affects up to 12 million Americans and confers an increased risk for development of esophageal adenocarcinoma (EAC). EAC is often fatal unless detected early. Given the high prevalence, high cost of surveillance a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539d187c42ef2f4df30415fb226e1111
https://doi.org/10.7150/jca.6990

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Pharmacokinetic Analysis of Dynamic

Autor: Jazmin, Schwartz, Milan, Grkovski, Andreas, Rimner, Heiko, Schöder, Pat B, Zanzonico, Sean D, Carlin, Kevin D, Staton, John L, Humm, Sadek A, Nehmeh

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(6)

Hypoxic tumors exhibit increased resistance to radiation, chemical, and immune therapies. 18F-fluoromisonidazole (18F-FMISO) PET is a noninvasive, quantitative imaging technique used to evaluate the magnitude and spatial distribution of tumor hypoxia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e05365ee9a4009b9558d294de5d87eaf
https://pubmed.ncbi.nlm.nih.gov/28232611

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Assessment of Nuclear Nano-morphology Markers for Predicting Cancer Progression Risk in Patients with Precancerous Breast Lesions

Autor: Hong Wang, Yang Liu, Zaibo Li, Atilla Soran, Shikhar Uttam, Kevin D. Staton, Rohit Bhargava, Randall E. Brand, Gretchen M. Ahrendt

Publikováno v: Biomedical Optics 2014.

We evaluate whether nano-morphology markers from cell nuclei derived from spatial-domain low-coherence quantitative phase microscopy from patients with precancerous breast lesios can identify high-risk patients for cancer progression.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6452fe50da2d1094d521ebd66db10157
https://doi.org/10.1364/biomed.2014.bw1a.4

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Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation

Autor: Serah Choi, Shikhar Uttam, Randall E. Brand, Yang Liu, Christopher J. Bakkenist, Sergey A. Alexandrov, Rajan K. Bista, Douglas J. Hartman, Kevin D. Staton

Publikováno v: ResearcherID
Biomedical Optics Express

We present depth-resolved spatial-domain low-coherence quantitative phase microscopy, a simple approach that utilizes coherence gating to construct a depth-resolved structural feature vector quantifying sub-resolution axial structural changes at diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705b692db561a470b24e64a409e507bd
https://pubmed.ncbi.nlm.nih.gov/24312743

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