Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kevin D. Rohrbacher"'
Autor:
Aaron H. Burstein, Marilyn Stolar, Kevin D. Rohrbacher, Hélène M. Faessel, Megan A. Gibbs, David J. Clark
Publikováno v:
The Journal of Clinical Pharmacology. 46:1439-1448
Varenicline is a novel and selective alpha4beta2 nicotinic acetylcholine receptor partial agonist developed for smoking cessation. The primary objectives of this double-blind, placebo-controlled, dose-escalation study were to determine the pharmacoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b966e0573053146c15e7b67fb01388
https://doi.org/10.1177/0091270006292624
https://doi.org/10.1177/0091270006292624
Autor:
Janice R. Thornton-Manning, John A. Stephens, Kevin D. Rohrbacher, Alan R. Dahl, Per Gerde, Gary G. Scott
Publikováno v:
Toxicology Methods. 8:17-25
In experiments to determine the toxicokinetics of polycyclic aromatic hydrocarbons (PAHs) in lungs at environmentally realistic levels, a technique to measure metabolites in tissueat subfemtomolar concentrations was needed. Postexposure blood concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37834a9e5467f705e25377c91becb88f
https://doi.org/10.1080/105172398243005
https://doi.org/10.1080/105172398243005
Autor:
M. D. Troutman, S. A. Willavize, David J. Clark, Aaron H. Burstein, Kevin D. Rohrbacher, Hélène M. Faessel
Publikováno v:
European journal of clinical pharmacology. 64(11)
This study investigated the effect of varenicline on the multiple-dose pharmacokinetics of digoxin.Eighteen smokers were randomized to receive digoxin (Lanoxicaps 0.2 mg QD) with varenicline 1 mg BID or placebo for 14 days.Varenicline had no clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a4a817d3c3296db81abe679c13bdcb
https://pubmed.ncbi.nlm.nih.gov/18661125
https://pubmed.ncbi.nlm.nih.gov/18661125
Autor:
Kelly J. Avila, Kristen J. Nikula, Janice R. Thornton-Manning, Xinxin Ding, Kevin D. Rohrbacher, Alan R. Dahl, Jon A. Hotchkiss
Publikováno v:
Toxicology and applied pharmacology. 142(1)
Two members of the cytochrome P450 2A subfamily, CYP2A10 and 2A11, are abundant nasal enzymes previously characterized in rabbit olfactory microsomes. Rabbit CYP2A is active toward a number of nasal toxicants, including the rat nasal procarcinogen he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8b09520fab4f82ed98ec2a736842b8
https://pubmed.ncbi.nlm.nih.gov/9007030
https://pubmed.ncbi.nlm.nih.gov/9007030