Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kevin D. Houston"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionInsulin-like growth factor binding protein-3 (IGFBP-3) exerts varying effects on estrogen receptor alpha (ERα)-positive and triple-negative breast cancer (TNBC) cells. In ERα-positive cells, IGFBP-3 is antiproliferative and proapoptotic
Externí odkaz:
https://doaj.org/article/ca609206b5bc4cacb51e299c7cfbd850
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Insulin-like growth factor (IGF) system plays a significant role in many cellular processes, including proliferation, and survival. In estrogen receptor positive breast cancer, the level of circulating IGF-1 is positively associated with the incidenc
Externí odkaz:
https://doaj.org/article/a5cb8d1534d149578120685a5c9bfd63
Tamoxifen is a common adjuvant treatment for estrogen receptor (ER)α-positive patients with breast cancer; however, acquired resistance abrogates the efficacy of this therapeutic approach. We recently demonstrated that G protein–coupled estrogen r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e5aa9f7d21a5acc755051bb03c06858
https://doi.org/10.1158/1541-7786.c.6540049.v1
https://doi.org/10.1158/1541-7786.c.6540049.v1
qPCR analysis of IGFBP-1 transcription after 24h treatment with vehicle or 10nM E2 in MCF-7 cells in serum-free condition. * = p < 0.05 and results are average or representative of three independent experiments. Error bars are SEM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b39452ab8ac635dc11194d47325d738
https://doi.org/10.1158/1541-7786.22511824.v1
https://doi.org/10.1158/1541-7786.22511824.v1
GPER1 and CREB expression and accumulation of p-CREB (S133) in MCF-7 and TamR cells. B, Accumulation of p-CREB (S133) after 2h Tam treatment in MCF-7 and TamR cells. * = p < 0.05 and results are average or representative of three independent experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694804259a7fe3c2710d82a81dcff44e
https://doi.org/10.1158/1541-7786.22511821
https://doi.org/10.1158/1541-7786.22511821
FoxO1 protein levels after 48 h of treatment with 5μM PPP in MCF-7 cells grown in DMEM containing 10% FBS. Results are average or representative of three independent experiments. Error bars are SEM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673777fc5ea2bdcc5c4eab69877b48e1
https://doi.org/10.1158/1541-7786.22511818.v1
https://doi.org/10.1158/1541-7786.22511818.v1
qPCR analysis of IGFBP-1 transcription after 24h treatment with vehicle or 1 µM Tam in absence and presence of actinomycin D (2 μg/ml) pretreatment in MCF-7 cells in serum-free condition. * = p < 0.05 and results are representative of two independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d085979ef301599b6841ace4340a099
https://doi.org/10.1158/1541-7786.22511827.v1
https://doi.org/10.1158/1541-7786.22511827.v1
qPCR analysis of IGFBP-1 transcription after 24h treatment with IGF-1 (50 ng/ml) in MCF-7 cells in serum-free condition. * = p < 0.05 and results are average or representative of three independent experiments. Error bars are SEM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b05c224fea816706f88f5f7cd65d30
https://doi.org/10.1158/1541-7786.22511812.v1
https://doi.org/10.1158/1541-7786.22511812.v1
Autor:
Cheryl Lyn Walker, Gordon B. Mills, David Kwiatkowski, Fuyuhiko Tamanoi, Susie Miyamoto, Jianjun Shen, Russell R. Broaddus, Charles L. Johnson, Jinhee Kim, Sheng-Li Cai, Ruhee Dere, Kevin D. Houston, John D. Short
Supplementary Figures 1-2, Table 1 from AMP-Activated Protein Kinase Signaling Results in Cytoplasmic Sequestration of p27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076e6b689a8018cd8418491ad092dfc8
https://doi.org/10.1158/0008-5472.22375097
https://doi.org/10.1158/0008-5472.22375097
Autor:
Cheryl Lyn Walker, Gordon B. Mills, David Kwiatkowski, Fuyuhiko Tamanoi, Susie Miyamoto, Jianjun Shen, Russell R. Broaddus, Charles L. Johnson, Jinhee Kim, Sheng-Li Cai, Ruhee Dere, Kevin D. Houston, John D. Short
Tuberin, the Tsc2 gene product, integrates the phosphatidylinositol 3-kinase/mitogen-activated protein kinase (mitogenic) and LKB1/AMP-activated protein kinase (AMPK; energy) signaling pathways, and previous independent studies have shown that loss o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9d482fdf9e73f9d203dfae6b3c00854
https://doi.org/10.1158/0008-5472.c.6497711
https://doi.org/10.1158/0008-5472.c.6497711