Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kevin D Augustijn"'
Autor:
Rachel P L van Swelm, Coby M M Laarakkers, Ellen C van der Kuur, Eva Morava-Kozicz, Ron A Wevers, Kevin D Augustijn, Daan J Touw, Maro H Sandel, Rosalinde Masereeuw, Frans G M Russel
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49524 (2012)
Drug-induced liver injury (DILI) is the leading cause of acute liver failure. Currently, no adequate predictive biomarkers for DILI are available. This study describes a translational approach using proteomic profiling for the identification of urina
Externí odkaz:
https://doaj.org/article/e72eb2e6d83c4354b2efc7eb581a84fb
Autor:
Richard Bucala, Edwin Siu, Luis Brito, Tiffany Sun, Erol Fikrig, Jürgen Bernhagen, Chris J. Janse, Armin Hekele, Alvaro Baeza Garcia, Andrew Geall, Valerie Exler, Kevin D. Augustijn, Jeffrey B. Ulmer, Gib Otten
Publikováno v:
Nature Communications, 9
Baeza Garcia, A, Siu, E, Sun, T, Exler, V, Brito, L, Hekele, A, Otten, G, Augustijn, K D, Janse, C, Ulmer, J, Bernhagen, J, Fikrig, E, Geall, A & Bucala, R 2018, ' Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection. ', Nature Communications, vol. 9, no. 2714, PMID: 30006528 . https://doi.org/10.1038/s41467-018-05041-7
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, 9(2714):PMID: 30006528. Nature Publishing Group
Nature Communications 9, 2714 (2018). doi:10.1038/s41467-018-05041-7
Baeza Garcia, A, Siu, E, Sun, T, Exler, V, Brito, L, Hekele, A, Otten, G, Augustijn, K D, Janse, C, Ulmer, J, Bernhagen, J, Fikrig, E, Geall, A & Bucala, R 2018, ' Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection. ', Nature Communications, vol. 9, no. 2714, PMID: 30006528 . https://doi.org/10.1038/s41467-018-05041-7
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, 9(2714):PMID: 30006528. Nature Publishing Group
Nature Communications 9, 2714 (2018). doi:10.1038/s41467-018-05041-7
Plasmodium species produce an ortholog of the cytokine macrophage migration inhibitory factor, PMIF, which modulates the host inflammatory response to malaria. Using a novel RNA replicon-based vaccine, we show the impact of PMIF immunoneutralization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fd3de4c63bfeade62e5883c151f580
http://hdl.handle.net/1887/86669
http://hdl.handle.net/1887/86669
Autor:
Kevin D. Augustijn, Eleanor J. Dodson, Anthony J. Wilkinson, Chris J. Janse, Andrew P. Waters, James A. Brannigan, Sarah E. Dobson, Claudia Schnick
Publikováno v:
Protein Science. 18:2578-2591
Malaria, caused by Plasmodium falciparum and related parasites, is responsible for millions of deaths each year, mainly from complications arising from the blood stages of its life cycle. Macrophage migration inhibitory factor (MIF), a protein expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7601b22e9e18290f97c89837c7cae48
https://doi.org/10.1002/pro.263
https://doi.org/10.1002/pro.263
Autor:
Rainer Wechselberger, Robert Kaptein, Dawn L. Duval, Kevin D. Augustijn, Peter C. van der Vliet, Arthur Gutierrez-Hartmann
Publikováno v:
Proceedings of the National Academy of Sciences. 99:12657-12662
The POU-domain transcription factor Pit-1 and Ets-1, a member of the ETS family of transcription factors, can associate in solution and synergistically activate the prolactin promoter by binding to a composite response element in the prolactin promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77729c2caf8a717769b0ca38f662cc57
https://doi.org/10.1073/pnas.192693499
https://doi.org/10.1073/pnas.192693499
Autor:
Brenda I. Hendriks-Stegeman, Pieternella Holthuizen, Peter C. van der Vliet, Maarten Jansen, Bert Bakker, Kevin D. Augustijn
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:1545-1550
The POU homeodomain containing transcriptional activator POU1F1, formerly called Pit1 or GHF-1, is required for the embryological determination and postnatal secretory function of the GH-, PRL-, and TSH-producing cells in the anterior pituitary. Seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14483cd01cac4b692e114e264a18b144
https://doi.org/10.1210/jcem.86.4.7371
https://doi.org/10.1210/jcem.86.4.7371
Autor:
Yan Song, Mehdi Nouraie, Victor R. Gordeuk, Tiffany Sun, Thomas Holowka, Richard Bucala, Lin Leng, Chris J. Janse, Huabao Xiong, Yibang Chen, Jason W. Griffith, Philip E. Thuma, Swen Zierow, Elias Lolis, Kevin D. Augustijn
Publikováno v:
Proceedings of the National Academy of Sciences, 109(31), E2117-E2126
The inability to acquire protective immunity against Plasmodia is the chief obstacle to malaria control, and inadequate T-cell responses may facilitate persistent blood-stage infection. Malaria is characterized by a highly inflammatory cytokine milie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9ef1dd60711b45e7938298177ef07a
https://hdl.handle.net/1887/109511
https://hdl.handle.net/1887/109511
Autor:
Rosalinde Masereeuw, Coby M. Laarakkers, Ron A. Wevers, Rachel P. L. van Swelm, Frans G. M. Russel, Eva Morava-Kozicz, Ellen C. van der Kuur, Kevin D. Augustijn, Daan J Touw, Maro H. Sandel
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49524 (2012)
PLoS One, 7, 11
PLoS ONE, 7(11):e49524. PUBLIC LIBRARY SCIENCE
van Swelm, R, Laarakkers, C M, van der Kuur, E C, Morava-Kozicz, E, Wevers, R A, Augustijn, K D, Touw, D J, Sandel, M H, Masereeuw, R & Russel, F G M 2012, ' Identification of novel translational urinary biomarkers for acetaminophen-induced acute liver injury using proteomic profiling in mice ', PLoS ONE, vol. 7, no. 11, e49524 . https://doi.org/10.1371/journal.pone.0049524
PLoS One, 7
PLoS ONE, 7(11):e49524. Public Library of Science
PLoS ONE
PLoS One, 7, 11
PLoS ONE, 7(11):e49524. PUBLIC LIBRARY SCIENCE
van Swelm, R, Laarakkers, C M, van der Kuur, E C, Morava-Kozicz, E, Wevers, R A, Augustijn, K D, Touw, D J, Sandel, M H, Masereeuw, R & Russel, F G M 2012, ' Identification of novel translational urinary biomarkers for acetaminophen-induced acute liver injury using proteomic profiling in mice ', PLoS ONE, vol. 7, no. 11, e49524 . https://doi.org/10.1371/journal.pone.0049524
PLoS One, 7
PLoS ONE, 7(11):e49524. Public Library of Science
PLoS ONE
Contains fulltext : 108207.pdf (Publisher’s version ) (Open Access) Drug-induced liver injury (DILI) is the leading cause of acute liver failure. Currently, no adequate predictive biomarkers for DILI are available. This study describes a translatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f500f220730f4a05680683b7bfd5ee
http://europepmc.org/articles/PMC3498140?pdf=render
http://europepmc.org/articles/PMC3498140?pdf=render
Autor:
Sally G. Moore, Andrew P. Waters, Maria M. Mota, Joanne Thompson, Chris J. Janse, Bruno Douradinha, Kevin D. Augustijn, Jai Ramesar
Publikováno v:
Douradinha, B, Augustijn, K D, Moore, S G, Ramesar, J, Mota, M M, Waters, A P, Janse, C J & Thompson, J 2011, ' Plasmodium Cysteine Repeat Modular Proteins 3 and 4 are essential for malaria parasite transmission from the mosquito to the host ', Malaria Journal, vol. 10, 71 . https://doi.org/10.1186/1475-2875-10-71
Malaria Journal
Malaria Journal, Vol 10, Iss 1, p 71 (2011)
Malaria Journal
Malaria Journal, Vol 10, Iss 1, p 71 (2011)
Background The Plasmodium Cysteine Repeat Modular Proteins (PCRMP) are a family of four conserved proteins of malaria parasites, that contain a number of motifs implicated in host-parasite interactions. Analysis of mutants of the rodent parasite Plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fff2844014b63add2e0634ab46c94e
https://www.pure.ed.ac.uk/ws/files/8144776/MJ_2011_Thompson_J.pdf
https://www.pure.ed.ac.uk/ws/files/8144776/MJ_2011_Thompson_J.pdf
Autor:
Sarah E, Dobson, Kevin D, Augustijn, James A, Brannigan, Claudia, Schnick, Chris J, Janse, Eleanor J, Dodson, Andrew P, Waters, Anthony J, Wilkinson
Publikováno v:
Protein Science : A Publication of the Protein Society
Malaria, caused by Plasmodium falciparum and related parasites, is responsible for millions of deaths each year, mainly from complications arising from the blood stages of its life cycle. Macrophage migration inhibitory factor (MIF), a protein expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1fc319d387e3c59969ec26ce494eff5
https://pubmed.ncbi.nlm.nih.gov/19827093
https://pubmed.ncbi.nlm.nih.gov/19827093
Autor:
Chris J. Janse, Sarah E. Reece, Carina E. Crawford, Robert Kleemann, Kevin D. Augustijn, Joanne Thompson, Teake Kooistra, Arjan H. G. Siebum, Andrew P. Waters, Arnab Pain
Publikováno v:
Augustijn, K D, Kleemann, R, Thompson, J, Kooistra, T, Crawford, C E, Reece, S E, Pain, A, Siebum, A H G, Janse, C J & Waters, A P 2007, ' Functional characterization of the Plasmodium falciparum and P-berghei homologues of macrophage migration inhibitory factor ', Infection and Immunity, vol. 75, no. 3, pp. 1116-1128 . https://doi.org/10.1128/IAI.00902-06
Macrophage migration inhibitory factor (MIF) is a mammalian cytokine that participates in innate and adaptive immune responses. Homologues of mammalian MIF have been discovered in parasite species infecting mammalian hosts (nematodes and malaria para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1aa7af604beef2403fab4265f5b50e6
https://hdl.handle.net/20.500.11820/8dbc58bb-3f02-4fa1-ae29-3fa3bba6f194
https://hdl.handle.net/20.500.11820/8dbc58bb-3f02-4fa1-ae29-3fa3bba6f194