Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kevin Cross"'
Autor:
Arianna Bassan, Ronald Steigerwalt, Douglas Keller, Lisa Beilke, Paul M. Bradley, Frank Bringezu, William J. Brock, Leigh Ann Burns-Naas, Jon Chambers, Kevin Cross, Michael Dorato, Rosalie Elespuru, Douglas Fuhrer, Frances Hall, Jim Hartke, Gloria D. Jahnke, Felix M. Kluxen, Eric McDuffie, Friedemann Schmidt, Jean-Pierre Valentin, David Woolley, Doris Zane, Glenn J. Myatt
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
The ICH S1B carcinogenicity global testing guideline has been recently revised with a novel addendum that describes a comprehensive integrated Weight of Evidence (WoE) approach to determine the need for a 2-year rat carcinogenicity study. In the pres
Externí odkaz:
https://doaj.org/article/3419c3b90a414f7aafa8e7a2a11aedc0
Autor:
Douglas A. Keller, Arianna Bassan, Alexander Amberg, Leigh Ann Burns Naas, Jon Chambers, Kevin Cross, Frances Hall, Gloria D. Jahnke, Amarjit Luniwal, Serena Manganelli, Jordi Mestres, Amy L. Mihalchik-Burhans, David Woolley, Raymond R. Tice
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
In silico toxicology protocols are meant to support computationally-based assessments using principles that ensure that results can be generated, recorded, communicated, archived, and then evaluated in a uniform, consistent, and reproducible manner.
Externí odkaz:
https://doaj.org/article/662e50fa83754807891531c6e030ecd7
Autor:
Laura Thornton PT, DPT, OCS, FAAOMPT, J. Brett Goodloe MD, Inga Groseclose PT, DPT, Kevin Cross PhD, PT, ATC, David R. Diduch MD
Publikováno v:
Video Journal of Sports Medicine, Vol 3 (2023)
Background: Reinjury rates following anterior cruciate ligament (ACL) reconstruction remain high, and the cause is often multifactorial. There is growing literature supporting asymmetric biomechanical deficits leading to increased risk of reinjury. N
Externí odkaz:
https://doaj.org/article/9256b453bcbd4e35b7195e99836ea3c0
Autor:
Alejandra Trejo-Martin, Joel P. Bercu, Andrew Thresher, Rachael E. Tennant, Robert F. Thomas, Kevin Cross, Andreas Czich, Kerstin Waese, John J. Nicolette, Joel Murray, Paul Sonders, Alison Kondratiuk, Jennifer R. Cheung, Dean Thomas, Anthony Lynch, James Harvey, Susanne Glowienke, Laura Custer, Patricia A. Escobar
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 135
Under ICH M7, impurities are assessed using the bacterial reverse mutation assay (i.e., Ames test) when predicted positive using in silico methodologies followed by expert review. N-Nitrosamines (NAs) have been of recent concern as impurities in phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1759d9f286318961dbbadf9f25dd9d92
https://pubmed.ncbi.nlm.nih.gov/35998738
https://pubmed.ncbi.nlm.nih.gov/35998738
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2425
In silico toxicology protocols help ensure the results from computational toxicology models are performed and documented in a standardized, consistent, transparent, and accepted manner. In silico toxicology protocols for skin sensitization and geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00bdaff2f3081cf8ebc5675c9f8e5c01
https://pubmed.ncbi.nlm.nih.gov/35188641
https://pubmed.ncbi.nlm.nih.gov/35188641
Autor:
Casey Moler, Kevin Cross, Mandeep Kaur, Amelia Bruce, Joseph M. Hart, David Diduch, Mark Miller, Brian Werner, Winston Gwathmey
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b806867dbe05e890d52bbb0801e6924
https://doi.org/10.2139/ssrn.4123813
https://doi.org/10.2139/ssrn.4123813
Autor:
Mark E. Roberts, Sandeep Daya, Denise Swift, Anesh Sitaram, Kevin Cross, Paul Owen, Richard Craggs, Shaun Hawley, Bev Isherwood
Publikováno v:
SLAS Technology. 21:143-152
Drug combination testing in the pharmaceutical industry has typically been driven by late-stage opportunistic strategies rather than by early testing to identify drug combinations for clinical investigation that may deliver improved efficacy. A ratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a15d55dfcfc383d5478073abe74ec61
https://doi.org/10.1177/2211068215579163
https://doi.org/10.1177/2211068215579163
Autor:
Kevin Cross, Paul Owen, Miranda Davis, Colin Bath, Dylan Griffith, Roger Northwood, Andrew Brierley, Ellen Simkiss, Andrew Slaney
Publikováno v:
SLAS Technology. 17:348-358
Compound management faces the daily challenge of providing high-quality samples to drug discovery. The advent of new screening technologies has seen demand for liquid samples move toward nanoliter ranges, dispensed by contactless acoustic droplet eje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33447adb82f350c3a4c7f24d5b96d363
https://doi.org/10.1177/2211068212457159
https://doi.org/10.1177/2211068212457159
Autor:
Kevin Cross
Publikováno v:
SAIS Review of International Affairs. 30:169-187
This paper examines the role of two variables in the confrontation between Green Movement reformists and the Iranian regime: social media and oil. Social media contributed to the size and intensity of the Green Movement; its effect on protests was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a99b01dbad376faf5b44b79437ce8b6
https://doi.org/10.1353/sais.2010.0008
https://doi.org/10.1353/sais.2010.0008
When three boys all run away from home to try and live like pirates life is easy at first. Then they meet Bonnie-Ann who trains them like real pirates...but their real talent turns out to be more musical...Race Further with Reading is the perfect too
