An overview of the unique challenges facing African-American breast cancer survivors

Autor: Timiya S. Nolan, Cassandra Grenade, Raquel E. Reinbolt, Maryam B. Lustberg, Kevin Chu Foy, Marium Husain

Publikováno v: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 27(3)

The existence of cancer disparities is well known. Focus on alleviating such disparities centers on diagnosis, treatment, and mortality. This review surveyed current knowledge of health disparities that exist in the acute survivorship period (immedia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f53f73244b4047f823aaf8d7bacbc78
https://pubmed.ncbi.nlm.nih.gov/30460398

Immunotherapy with HER-2 and VEGF peptide mimics plus metronomic paclitaxel causes superior antineoplastic effects in transplantable and transgenic mouse models of human breast cancer

Autor: Tatjana Bozanovic, William E. Carson, Megan J. Miller, Kevin Chu Foy, Nicanor Moldovan, Pravin T. P. Kaumaya

Publikováno v: Oncoimmunology

HER-2 and the vascular endothelial factor receptor (VEGF) represent validated targets for the therapy of multiple tumor types and inhibitors of these receptors have gained increasing importance in the clinic. In this context, novel bioactive agents a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75e59b45853ee08d0070a4fbb30ae13
https://doi.org/10.4161/onci.21057

Phase I Active Immunotherapy With Combination of Two Chimeric, Human Epidermal Growth Factor Receptor 2, B-Cell Epitopes Fused to a Promiscuous T-Cell Epitope in Patients With Metastatic and/or Recurrent Solid Tumors

Autor: Kevin Chu Foy, Jeffrey M. Fowler, Daniele Vicari, William E. Carson, Aruna Mani, Charles L. Shapiro, Donald Chalupa, Jennifer Thurmond, Joan T. Garrett, Tammy Lamb, Catherine Balint, Sharad Rawale, Pravin T. P. Kaumaya, Gregory A. Otterson, Tanios Bekaii-Saab, Michael R. Grever, Yahaira Kane

Publikováno v: Journal of Clinical Oncology. 27:5270-5277

Purpose To evaluate the maximum-tolerated dose (MTD), safety profile, and immunogenicity of two chimeric, B-cell epitopes derived from the human epidermal growth factor receptor (HER2) extracellular domain in a combination vaccine with a promiscuous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a8afd5b8b0d81a35e6f8c3a5319a0c
https://doi.org/10.1200/jco.2009.22.3883

Peptide vaccines and peptidomimetics of EGFR (HER-1) ligand binding domain inhibit cancer cell growth in vitro and in vivo

Autor: Megan J. Miller, Pravin T. P. Kaumaya, Jay Overholser, Ruthie M. Wygle, Tanios Bekaii-Saab, Kevin Chu Foy

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 191(1)

Epidermal growth factor receptor (EGFR) is a validated target for several cancers including lung, colorectal, and certain subtypes of breast cancer. Cetuximab targets ligand binding of EGFR, but major problems like high cost, short t1/2, toxicity, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9e31a30ee860ada2239de932a51c7d
https://pubmed.ncbi.nlm.nih.gov/23698748

Contributors

Autor: Reidunn B. Aalen, Yasser H.A. Abdel-Wahab, Michael E. Adams, Roger A.H. Adan, Rexford S. Ahima, Naima Ahmed, Omar Al-Massadi, Miriam Altstein, Youssef Anouar, Laura Anselmi, Siegfried Ansorge, Nikolinka Antcheva, Yevgeniya Antonova-Koch, Jon R. Appel, Anam J. Arik, Alison L. Arter, Peter Arvan, Avraham Ashkenazi, P.W. Baas, André Bado, Andrew Baird, Monica Baiula, Lauren O. Bakaletz, Earl E. Bakken, Márta Balaskó, Graham S. Baldwin, William A. Banks, Donatella Barra, Jessica R. Barson, Magali Basille, Natalie N. Bauer, Andrea Bedini, Christine Beeton, David J. Begley, Margery C. Beinfeld, William G. Bendena, Stephen C. Benoit, Itay Bentov, Howard Bern, Gabriele Bierbaum, Charles J. Billington, Anna Blasiak, Norman L. Block, Stephen. R. Bloom, Iwona Bonney, John H. Bowie, Sunny K. Boyd, Susan D. Brain, Dag A. Brede, Jozef Vanden Broeck, Kelly L. Brown, Mark R. Brown, James M. Bugni, Jens R. Bundgaard, Delphine Burel, Melinka A. Butenko, Melissa J. Call, Girolamo Calò, Duncan John Campbell, Anna Carlsson, Daniel B. Carr, Robert E. Carraway, Marcos C. Carreira, Felipe F. Casanueva, Sarah N. Cassella, Stuart A. Casson, Justo P. Castaño, Marek Cebrat, Valerie Chappe, David Chatenet, Keqiang Chen, Chen Chen, Longchuan Chen, Duan Chen, Carrie Y.Y. Cheng, Sung Ki Cho, Billy K.C. Chow, Arthur Christopoulos, Shijian Chu, Iain J. Clarke, Geoffrey M. Coast, Vincent Compere, Gisela P. Concepcion, Roger D. Cone, J. Michael Conlon, Germaine Cornélissen, Maité Courel, Réjean Couture, W.A. Cramer, Nathan P. Croft, Ana B. Crujeiras, Frank Cuttitta, Holger Cynis, F. D’Acquisto, Jon F. Davis, Thomas P. Davis, Claire Barbier de La Serre, Guillaume de Lartigue, Luis de Lecea, Marcelo de Oliveira Santos, Michel De Waard, Carolyn F. Deacon Bolette Hartmann, Charlène Delestre, Mario Delgado, Hans-Ulrich Demuth, Xiaoming Deng, Palitha Dharmawardhana, Anna Di Cosmo, Simoni Campos Dias, Jonathan W. Dickerson, Dzung B. Diep, H. Dircksen, Jasmin Dischinger, Jean-Claude do Rego, Paul R. Dobner, Graham J. Dockray, Robert M. Dores, Robert Ducroc, Nadine L. Dudek, Yvan Dumont, Celine Duraffourd, Dominique Duterte-Boucher, Alex N. Eberlé, Richard D. Egleton, Betty A. Eipper, Jorg B. Engel, Ella W. Englander, Jacques Epelbaum, Charlotte Erlanson-Albertsson, S. Evangelista, Karen A. Fagan, Joshua M. Farber, Klára Farkasfalvi, Csaba Fekete, Peter R. Flatt, R.J. Flower, Wolf-Georg Forssmann, Alain Fournier, Kevin Chu Foy, Octávio Luiz Franco, Dan Frenkel, Lloyd D. Fricker, César de la Fuente-Núñez, Hiroo Fukuda, Gerd Gäde, Ludovic Galas, Patricia E. Gallagher, Pierrick Gandolfo, Maria A. Garcia-Espinosa, Josune García-Sanmartín, Nori Geary, Hua Geng, Patrizia M. Germano, Jens P. Goetze, Alexis A. Gonzalez, Ana Gonzalez, Blake A. Gosnell, Katsutoshi Goto, Guillaume Gourcerol, I. Gozes, Francisco Gracia-Navarro, Bernadette E. Grayson, George H. Greeley, Megan Greenwald-Yarnell, Pierre Gressens, John R. Grider, Jan Grünewald, Juliano R. Guerreiro, Remo Guerrini, Filomena Guida, Laure Guilhaudis, Sandra Guilmeau, Andrew L. Gundlach, Jolanta Gutkowska, Clifton Hackbarth, Y. Haim Ohana, Franz Halberg, Mathias Hallberg, Sayyed A. Hamidi, Song Han, Ji-Sheng Han, Robert E.W. Hancock, Samer-ul Haque, Ikuko Hara-Nishimura, Aliza Hariton, Wendy J. Hartsock, Alan L. Harvey, Itaru Hasunuma, Robert J. Henning, Kristy M. Heppner, Kate L. Hertweck, Herbert Herzog, Tetsuya Higashiyama, Shuji Hinuma, Stefan Hippenstiel, Yuki Hirakawa, Shuichi Hirose, Jochen R. Hirsch, Andreas C. Hocke, Robert S. Hodges, Werner Hoffmann, Tomas Hökfelt, Jens Juul Holst, Peter Holzer, Frank M. Horodyski, Hiroshi Hosoda, Xiaowen Hou, Alisa Huffaker, Norio Iijima, Momoko Ikeuchi, Julita S. Imperial, Giovanna Improta, Akio Inui, Nigel Irwin, Munehiro Ishii, Xavier Iturrioz, Ljubica Ivanisevic, Hiroshi Iwao, Takeo Iwata, Yasukatsu Izumi, Hajime Izumiyama, Marek Jankowski, Tom Janssen, Sylvie Jégou, Robert T. Jensen, Preeti H. Jethwa, Helene Johannessen, Conrad Johanson, Valeria Judkowski, Przemyslaw Kaczmarek, Haruaki Kageyama, Tatsuo Kakimoto, Ki Sung Kang, Kenji Kangawa, Abba J. Kastin, Johji Kato, Pravin T.P. Kaumaya, Richard F. Keep, William R. Kem, Tetyana Khomenko, Sakae Kikuyama, Young-Joon Kim, Sadao Kimura, Ross King, Paul Kiptoo, Ichiro Kishimoto, Kazuo Kitamura, Alicja Kluczyk, Hiroyuki Kobori, Yosuke Kodama, Masayasu Kojima, Yuki Kondo, Meike Körner, Piotr Kosson, Catherine M. Kotz, Bhavani Krishnan, Bård Kulseng, Robert Kumpf, Marc Laburthe, Hélène Lacaille, Ellen E. Ladenheim, Ali Ladram, Marlyn D. Laksitorini, David G. Lambert, Angela B. Lange, Wolfgang Langhans, Muriel Larauche, Dan Larhammar, Ignacio M. Larráyoz, Roberta Lattanzi, Ronald M. Lechan, Benjamin Lefranc, Sarah F. Leibowitz, Vincent Lelièvre, Jérôme Leprince, Allen S. Levine, Qun Li, Veronica Lifshitz, Isabelle Lihrmann, James Chi-Jen Lin, Iris Lindberg, Keith Lindsey, Andrzej W. Lipkowski, T. Liron, Junli Liu, Ying Liu, Min Liu, Catherine Llorens-Cortes, Marilena Loizidou, C. Lopez, David A. Lovejoy, Vincenzo Luca, Thomas A. Lutz, Sherie Ma, Richard E. Mains, Maria M. Malagon, Ludwik K. Malendowicz, Jennifer Man-Fan Wan, Maria Luisa Mangoni, Michaele B Manigrasso, Mohamed A. Marahiel, Heather G. Marco, Christine Maric-Bilkan, Nikki J. Marks, Roland Martin, Vicente Martinez, Alfredo Martínez, Antonio J. Martinez-Fuentes, Edward P. Masler, Yoshikatsu Matsubayashi, Harman S. Mattu, Aaron G. Maule, Patricia J. McLaughlin, Ivan F. McMurtry, Ellen Meelkop, Saher Mehdi, Pietro Melchiorri, R.P. Millar, Laurence J. Miller, Miles Miller, Mulugeta Million, Naoto Minamino, M. Mittelman, Takashi Miyauchi, Mikiya Miyazato, Hirokazu Mizoguchi, Malte Mohme, Maité Montero-Hadjadje, Terry W. Moody, Neeloffer Mookherjee, Timothy H. Moran, Irene Morganstern, Masatomo Mori, Fabrice Morin, John F. Morris, Daniel S. Moura, Anna J. Mudge, Joram D. Mul, Karnam S. Murthy, Martin G. Myers, Ronald J. Nachman, Jean-Louis Nahon, Sushma Naithani, Tomoaki Nakada, Tomoya Nakamachi, Yuki Nakamura, Natalia N. Nalivaeva, June B. Nasrallah, Dick R. Nässel, L. Gabriel Navar, Pratap Neelakantan, Lucia Negri, Ingolf F. Nes, D. Neumann, Cindy Neveu, Tzi Bun Ng, Stephanie Y.L. Ng, Graham M. Nicholson, Pierre Nicolas, Toshio Nishikimi, Mariko Nishiyama, Rubén Nogueiras, Raymond S. Norton, Laura A. Novotny, Krzysztof W. Nowak, Fred Nyberg, Laura Ochoa-Callejero, Sven Ove Ögren, Hideko Ohgusu, Shinsuke Oh-I, Opeolu O. Ojo, Baldomero M. Olivera, Francisco E. Olucha-Bordonau, Joost J. Oppenheim, Ian Orchard, André J. Ouellette, Gustavo Pacheco-López, Nigel M. Page, Mario Sergio Palma, Weihong Pan, Yoonseong Park, Marc Parmentier, Sandrine Passemard, Michael Patterson, Brankica Paunovic, Gregory Pearce, Jens Pedersen, Theo L. Peeters, A. Eugene Pekary, Georges Pelletier, Simona Perboni, Diego Pérez-Tilve, Ábel Perjés, M. Perretti, Erika Pétervári, Clemencia Pinilla, Jacek Pinskim, Joseph R. Pisegna, Kristof Plankensteiner, Sonia Podvin, Pierre Poitras, Gianluca Polese, David M. Pollock, William Farias Porto, Lourival D. Possani, Charalabos Pothoulakis, Françoise Presse, Minolfa C. Prieto, S. Prutchi-Sagiv, Anthony W. Purcell, Louise Purtell, Rémi Quirion, Catalina Abad Rabat, Miriam Rademaker, Gautam Rajpal, Harpal S. Randeva, Sylvie Rebuffat, Joseph R. Reeve, Jens F. Rehfeld, Dirk Reinhold, Rainer K. Reinscheid, Jean Claude Reubi, Katayoun Rezvani, Suzana Meira Ribeiro, D. Richard, Mark Richards, Michael A. Riehle, Andrea C. Rinaldi, Bernd M. Rode, Ricardo C. Rodríguez de la Vega, Susan Rotzinger, Marcin Rucinski, Heikki Ruskoaho, Philip J. Ryan, Jean-Marc Sabatier, Hans-Georg Sahl, Sami I. Said, Tsukasa Sakurada, Shinobu Sakurada, David S. Salomon, Willis K. Samson, Zsuzsanna Sandor, H. Uri Saragovi, Kazuki Sasaki, Takahiro Sato, Ryousuke Satou, Shinichiro Sawa, Ayman I. Sayegh, Andrew V. Schally, Stephan Schilling, Liliane Schoofs, David A. Schooley, Mitchell L. Schubert, Isabelle Segalas-Milazzo, Nabil G. Seidah, Michael E. Selsted, Kim B. Seroogy, Cinzia Severini, Patrick M. Sexton, Yechiel Shai, O. Sharma, Masayoshi Shichiri, Tomoo Shimada, Hiroyuki Shimizu, Seiji Shioda, Arthur Shulkes, Teruna J. Siahaan, Ignacy Z. Siemion, Osmar Nascimento Silva, Marcio C. Silva-Filho, Mariusz Skwarczynski, Caroline. J. Small, Craig M. Smith, David E. Smith, A. Ian Smith, Beka Solomon, Travis E. Solomon, Mireia Sospedra, M.C. Souroujon, Santi Spampinato, Eliot R. Spindel, A. Steiger, Andreas Stengel, Catia Sternini, Frederik J. Steyn, Edward Stopa, Mathias Z. Strowski, Shigeo S. Sugano, Görel Sundström, J. Gregor Sutcliffe, Norbert Suttorp, Jonathan V. Sweedler, Sandor Szabo, Miklós Székely, István Szokodi, Yvette Taché, Kazuhiro Takahashi, Yoshio Takei, Fumiko Takenoya, Sébastien Talbot, E. Ann Tallant, Tricia M. Tan, Liesbet Temmerman, Bettina Temmesfeld-Wollbrück, Manuel Tena-Sempere, Annika Thorsell, Nanda Tilakaratne, Stephen S. Tobe, Takeshi Tokudome, Ganna Tolstanova, Marie-Christine Tonon, Jennifer F. Topping, Alessandro Tossi, Hervé Tostivint, Istvan Toth, Kazuhito Totsune, Fumiyo Toyoda, Rachel Troke, Matthias H. Tschöp, Patrick Tso, Hirokazu Tsukaya, Kazuyoshi Tsutsui, Hong Tu, Anthony J. Turner, Takayoshi Ubuka, Elene R. Valdivia, Hans Peter Vandersmissen, David Vaudry, Hubert Vaudry, Rafael Vazquez-Martinez, Joseph G. Verbalis, Daniele Vicari, Nicolas Vidal, Marzia Vignoni, Cécile Viollet, K.S. Vishwanatha, Mirella Vivoli, Thierry Voisin, John P. Vu, John C. Walker, B.A. Wallace, Ji Ming Wang, Lixin Wang, Jonathan H. Wardman, Takuya Watanabe, Hazel Welch, Haim Werner, L. Whitmore, Imke Wiedemann, Raphaelle Winsky-Sommerer, Ken A. Witt, Tatiana Wojciechowicz, Jack Ho Wong, Stephen C. Woods, Denise Wootten, Vincent Wu, Olivier Wurtz, Ximing Xiong, Zhi-Qing David Xu, Yube Yamaguchi, Takahiro Yamaguchi, Kazutoshi Yamamoto, E. Yamashita, Hiroyuki Yamazaki, De Yang, Masaaki Yoshikawa, Pu-Qing Yuan, Sunny C. Yung, Ian S. Zagon, S.D. Zakharov, Mehfuz Zaman, M.V. Zhalnina, Ning Zhang, Lixin Zhang-Auberson, Chun-Mei Zhao, Agnieszka Ziolkowska, Dusan Zitnan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e448f641ad87b625202ba857fd542cb
https://doi.org/10.1016/b978-0-12-385095-9.01002-2