Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Kevin C. Slep"'
Publikováno v:
PLoS ONE, Vol 18, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/e0470ea4a5604934b175fa208a6f237c
Autor:
Brian J. Galletta, Carey J. Fagerstrom, Todd A. Schoborg, Tiffany A. McLamarrah, John M. Ryniawec, Daniel W. Buster, Kevin C. Slep, Gregory C. Rogers, Nasser M. Rusan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
The centrosome is a large intracellular structure that serves as the microtubule-organising center, but how it is accurately assembled is not known. Here the authors generate a ‘domain-level’ centrosome interactome and show that Plk4 positions th
Externí odkaz:
https://doaj.org/article/bd602ba043d3456eb55d85545a7af134
Autor:
John M. Ryniawec, Daniel W. Buster, Lauren K. Slevin, Cody J. Boese, Anastasia Amoiroglou, Spencer M. Dean, Kevin C. Slep, Gregory C. Rogers
Publikováno v:
Molecular Biology of the Cell.
Polo-like kinase 4 (Plk4) is the master-regulator of centriole assembly and cell cycle-dependent regulation of its activity maintains proper centrosome number. During most of the cell cycle, Plk4 levels are nearly undetectable due to its ability to a
Epidermal cells of dark-grown plant seedlings reorient their cortical microtubule arrays in response to blue light from a net lateral orientation to a net longitudinal orientation with respect to the long axis of cells. The molecular mechanism underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::614e23ad3043525188c10e15f38310e4
https://doi.org/10.1101/2022.12.28.522140
https://doi.org/10.1101/2022.12.28.522140
Autor:
Leonardo Salviati, Bruno Dallapiccola, Emanuele Agolini, Daniela Zuccarello, Antonio Novelli, Enrico Grosso, Simone Martinelli, Eva Trevisson, Valeria Morbidoni, Kevin C. Slep, Matteo Cassina, Giorgia Gai, Luca Pannone
Publikováno v:
Journal of Medical Genetics. 58:526-533
BackgroundDysfunction in non-motile cilia is associated with a broad spectrum of developmental disorders characterised by clinical heterogeneity. While over 100 genes have been associated with primary ciliopathies, with wide phenotypic overlap, some
Autor:
Kevin C. Slep
Publikováno v:
Current Biology. 30:R646-R649
Summary While the dynamics of microtubule ends are well characterized, the mechanism that repairs breaks in the lattice interior is poorly understood. A new in vitro study finds that the microtubule-associated protein CLASP repairs lattice damage by
Autor:
Kevin C. Slep, Cody J. Boese, Anastasia Amoiroglou, Lauren K. Slevin, Spencer Dean, John M. Ryniawec, Gregory C. Rogers, Daniel W. Buster
Polo-like kinase 4 (Plk4) is the master-regulator of centriole assembly and cell cycle-dependent regulation of its activity maintains proper centrosome number. During most of the cell cycle, Plk4 levels are nearly undetectable due to its ability to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce93cb21af899ac63b910c1724da171
https://doi.org/10.1101/2021.11.15.468682
https://doi.org/10.1101/2021.11.15.468682
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144174 (2015)
CP190 is a large, multi-domain protein, first identified as a centrosome protein with oscillatory localization over the course of the cell cycle. During interphase it has a well-established role within the nucleus as a chromatin insulator. Upon nucle
Externí odkaz:
https://doaj.org/article/96910ba504bd4ff69e70c8c978b6148f
Embryogenesis requires cells to change shape and move without disrupting epithelial integrity. This requires robust, responsive linkage between adherens junctions and the actomyosin cytoskeleton. Using Drosophila morphogenesis we define molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a859b07f87be43c5746181ec2f0dd25
https://doi.org/10.1101/2021.05.04.442628
https://doi.org/10.1101/2021.05.04.442628
Autor:
Kevin C. Slep, Kristi D. Yow, Amy E. Byrnes, Kia Z. Perez-Vale, Mark Peifer, Ruth I. Johnson, Tara M. Finegan
Publikováno v:
The Journal of cell biology. 220(12)
Embryogenesis requires cells to change shape and move without disrupting epithelial integrity. This requires robust, responsive linkage between adherens junctions and the actomyosin cytoskeleton. Using Drosophila morphogenesis, we define molecular me