Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kevin C. Potter"'
Publikováno v:
The Plant Journal. 107:1387-1402
Cytokinins regulate diverse aspects of plant growth and development, primarily through modulation of gene expression. The cytokinin-responsive transcriptome has been thoroughly described in dicots, especially Arabidopsis, but much less so in monocots
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830b7ab37f46cc651b9428819554957d
https://doi.org/10.1111/tpj.15386
https://doi.org/10.1111/tpj.15386
Publikováno v:
Biochem J
All land plants contain at least one class II diterpene cyclase (DTC), which utilize an acid-base catalytic mechanism, for the requisite production of ent-copalyl diphosphate (ent-CPP) in gibberellin A (GA) phytohormone biosynthesis. These ent-CPP sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deff61401807688021caa05d13b2cd1b
https://doi.org/10.1042/bcj20190479
https://doi.org/10.1042/bcj20190479
Cytokinin modulates context-dependent chromatin accessibility through the type-B response regulators
Publikováno v:
Nature Plants. 4:1102-1111
The phytohormone cytokinin regulates diverse aspects of plant growth and development, probably through context-dependent transcriptional regulation that relies on a dynamic interplay between regulatory proteins and chromatin. We employed the assay fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b0ecec9b7b0f2a6cded196b04a95a1
https://doi.org/10.1038/s41477-018-0290-y
https://doi.org/10.1038/s41477-018-0290-y
Extreme promiscuity of a bacterial and a plant diterpene synthase enables combinatorial biosynthesis
Publikováno v:
Metabolic Engineering. 37:24-34
Diterpenes are widely distributed across many biological kingdoms, where they serve a diverse range of physiological functions, and some have significant industrial utility. Their biosynthesis involves class I diterpene synthases (DTSs), whose activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2061a4d429937da772cef8bfc123308c
https://doi.org/10.1016/j.ymben.2016.04.001
https://doi.org/10.1016/j.ymben.2016.04.001
Publikováno v:
Organic letters, vol 18, iss 5
Organic Letters
Organic Letters
Through site-directed mutagenesis targeted at identification of the catalytic base in the rice (Oryza sativa) syn-copalyl diphosphate synthase OsCPS4, changes to a single residue (H501) were found to induce rearrangement rather than immediate deproto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1de4df07d590774eb2a7ff2ddacf6ab
https://doi.org/10.1021/acs.orglett.6b00181
https://doi.org/10.1021/acs.orglett.6b00181
Plants from the widespread Lamiaceae family produce many labdane-related diterpenoids, a number of which serve medicinal roles, and whose biosynthesis is initiated by class II diterpene cyclases (DTCs). These enzymes utilize a general acid-base catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b560690b3ca2eadd6fbcbde5b9ab43df
https://resolver.caltech.edu/CaltechAUTHORS:20180718-143536056
https://resolver.caltech.edu/CaltechAUTHORS:20180718-143536056
Autor:
Kevin C. Potter, Reuben J. Peters, Brandi Malchow, Jiachen Zi, Samuel Schulte, Dean J. Tantillo, Young J. Hong
Publikováno v:
Angewandte Chemie (International ed. in English), vol 55, iss 2
Substitution of a histidine, comprising part of the catalytic base group in the ent-copalyl diphosphate synthases found in all seed plants for gibberellin phytohormone metabolism, by a larger aromatic residue leads to rearrangements. Through a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f4767267d5f74fe4d5ce2b03b44f69
https://doi.org/10.1002/ange.201509060
https://doi.org/10.1002/ange.201509060
Publikováno v:
Angewandte Chemie. 126:7326-7330
An active-site water molecule coordinated by conserved histidine and asparagine residues seems to serve as the catalytic base in all ent-copalyl diphosphate synthases (CPSs). When these residues are substituted by alanine, the mutant CPSs produce ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570eebf6949244e80810d6115d9e9466
https://doi.org/10.1002/ange.201402911
https://doi.org/10.1002/ange.201402911
Autor:
Samuel Schulte, Kevin C. Potter, Sibongile Mafu, Jared Criswell, Reuben J. Peters, Matthew L. Hillwig
Publikováno v:
Chemical Communications. 51:13485-13487
While cyclic ether forming terpene synthases are known, the basis for such heterocyclisation is unclear. Here it is reported that numerous (di)terpene synthases, particularly including the ancestral ent-kaurene synthase, efficiently produce isomers o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b63b880d696cd18ee4a3c996b9af32
https://doi.org/10.1039/c5cc05754j
https://doi.org/10.1039/c5cc05754j
Background The diterpene cyclase ent-copalyl diphosphate synthase (CPS) catalyzes the first committed step in the biosynthesis of gibberellins. The previously reported 2.25 Å resolution crystal structure of CPS complexed with (S)-15-aza-14,15-dihydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af78c8d0d502b546befc53f7542f9e3
http://hdl.handle.net/11147/5650
http://hdl.handle.net/11147/5650