Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Kevin C. Mange"'
Autor:
David Cipolla, Jimin Zhang, Brice Korkmaz, James D. Chalmers, Jessica Basso, Daniel Lasala, Carlos Fernandez, Ariel Teper, Kevin C. Mange, Walter R. Perkins, Eugene J. Sullivan
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Brensocatib is an oral, selective, reversible inhibitor of dipeptidyl peptidase-1 (DPP-1), responsible for activating neutrophil serine proteases (NSPs) including neutrophil elastase (NE), proteinase 3 (PR3), and cathepsin G (CatG
Externí odkaz:
https://doaj.org/article/85f654da54af4f9a8406df384ca1cca2
Autor:
Christina M. Mingora, Bryan A. Garcia, Kevin C. Mange, Dayton W. Yuen, Monika Ciesielska, Jakko van Ingen, Patrick A. Flume, Susan E. Dorman
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Mycobacterial time to positivity (TTP) in liquid culture media has predictive value for longer term outcomes in pulmonary tuberculosis, but has not been thoroughly studied in nontuberculous mycobacterial pulmonary disease. This st
Externí odkaz:
https://doaj.org/article/7b1d4996b7d64463afa4fa76822397c2
Autor:
Theodore K. Marras, Mariam Hassan, Kevin C. Mange, Monika Ciesielska, Shilpa Dhar Murthy, Zhanna Jumadilova, Anjan Chatterjee
Publikováno v:
ERJ Open Research, Vol 8, Iss 3 (2022)
Externí odkaz:
https://doaj.org/article/cbc83b69f5b94fd3a566773c04c2a933
Autor:
James D. Chalmers, Helen Usansky, Christopher M. Rubino, Ariel Teper, Carlos Fernandez, Jun Zou, Kevin C. Mange
Publikováno v:
Clinical Pharmacokinetics. 61:1457-1469
Brensocatib is an investigational, first-in-class, selective, and reversible dipeptidyl peptidase 1 inhibitor that blocks activation of neutrophil serine proteases (NSPs). The NSPs neutrophil elastase, cathepsin G, and proteinase 3 are believed to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31cb7d98a544e60ea923eb0c19ce875
https://doi.org/10.1007/s40262-022-01147-w
https://doi.org/10.1007/s40262-022-01147-w
Publikováno v:
Chest
Background Nontuberculous mycobacterial pulmonary disease (NTM-PD) is an uncommon mycobacterial infection characterized by worsening lung function and increased health care resource utilization; however, the overall risk for hospitalization among pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993f8c806e35061c45935e51562053d2
https://doi.org/10.1016/j.chest.2021.07.034
https://doi.org/10.1016/j.chest.2021.07.034
Autor:
Timothy R. Aksamit, Richard J. Wallace, Dayton W. Yuen, Kozo Morimoto, Wouter Hoefsloot, David E. Griffith, Doreen Addrizzo-Harris, Kevin L. Winthrop, Kevin C. Mange, Monika Ciesielska, Rachel Thomson, Jakko van Ingen, Chris Coulter, Stephen K. Field, Patrick A. Flume, Barbara A. Brown-Elliott
Publikováno v:
Chest. 160:831-842
Background: In the CONVERT study, treatment with amikacin liposome inhalation suspension (ALIS) added to guideline-based therapy (GBT) met the primary end point of increased culture conversion by month 6 in patients with treatment-refractory Mycobact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce5263ae6c0f4e6424f8686ff8b0332
https://doi.org/10.1016/j.chest.2021.03.070
https://doi.org/10.1016/j.chest.2021.03.070
Autor:
Dayton W. Yuen, Nikolas J. Onufrak, Christopher M. Rubino, Jakko van Ingen, David E. Griffith, Kevin C. Mange, Kevin L. Winthrop, Sujata M. Bhavnani
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
European Journal of Drug Metabolism and Pharmacokinetics, 46, 277-287
European Journal of Drug Metabolism and Pharmacokinetics, 46, 2, pp. 277-287
European Journal of Drug Metabolism and Pharmacokinetics, 46, 277-287
European Journal of Drug Metabolism and Pharmacokinetics, 46, 2, pp. 277-287
Background and Objectives Use of parenteral amikacin to treat refractory nontuberculous mycobacterial (NTM) lung disease is limited by systemic toxicity. A population pharmacokinetic model was developed using data pooled from two randomized trials to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d16980a61a948d84c59c434de74690a
https://doi.org/10.1007/s13318-020-00669-7
https://doi.org/10.1007/s13318-020-00669-7
Autor:
Theodore K, Marras, Mariam, Hassan, Kevin C, Mange, Monika, Ciesielska, Shilpa Dhar, Murthy, Zhanna, Jumadilova, Anjan, Chatterjee
Publikováno v:
ERJ open research. 8(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6984a8f54dd346d088b1fbf2462924f
https://pubmed.ncbi.nlm.nih.gov/35821755
https://pubmed.ncbi.nlm.nih.gov/35821755
Autor:
Christina M. Mingora, Bryan A. Garcia, Kevin C. Mange, Dayton W. Yuen, Monika Ciesielska, Jakko van Ingen, Patrick A. Flume, Susan E. Dorman
Publikováno v:
BMC Infectious Diseases, 22, 1
BMC Infectious Diseases, 22
BMC Infectious Diseases, 22
Background Mycobacterial time to positivity (TTP) in liquid culture media has predictive value for longer term outcomes in pulmonary tuberculosis, but has not been thoroughly studied in nontuberculous mycobacterial pulmonary disease. This study sough
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8686f00447069a81efd61089ef1c29ee
https://pubmed.ncbi.nlm.nih.gov/35279081
https://pubmed.ncbi.nlm.nih.gov/35279081
Autor:
Ariel Teper, Kevin C. Mange, Christopher M. Rubino, Helen Usansky, Carlos Fernandez, James D. Chalmers
Publikováno v:
Respiratory infections and bronchiectasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1686af4903d2dc75f0bdb1aec6167eba
https://doi.org/10.1183/13993003.congress-2021.rct4268
https://doi.org/10.1183/13993003.congress-2021.rct4268