Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Kevin C. Langry"'
Autor:
Xuhong Zhang, Kevin M. Smith, Tadashi Yoshida, Kevin C. Langry, Li-Hua Ma, Yangzhong Liu, Gerd N. La Mar
Publikováno v:
Journal of the American Chemical Society. 128:6391-6399
The hydrogen bonding of ligated water in ferric, high-spin, resting-state substrate complexes of heme oxygenase from Neisseria meningitidis has been systematically perturbed by variable electron-withdrawing substituents on the hemin periphery. The pa
Autor:
Kevin C. Langry, Michael J. Allen, Rodney L. Balhorn, Timothy V. Ratto, Robert E. Rudd, Michael W. Mcelfresh
Publikováno v:
Biophysical Journal. 86(4):2430-2437
We present the measurement of the force required to rupture a single protein-sugar bond using a methodology that provides selective discrimination between specific and nonspecific binding events and helps verify the presence of a single functional mo
Publikováno v:
The European Physical Journal Applied Physics. 18:9-15
A systematic investigation on growth and sensor characteristics of SnO2 thin films of different orientations is reported for the first time. Thin films were grown by pulsed laser (KrF; λ = 248 nm) ablation technique under in-situ conditions. Films d
Autor:
Kevin C. Langry, Bobba Rambabu
Publikováno v:
Journal of Chemical Technology & Biotechnology. 74:717-732
Fiber optic chemical sensors and solid state devices are two versatile sensing technologies for detecting analytes in a host of media. Obvious differences distinguish these technologies: however, they share significant features and issues related to
Autor:
Gerd N. La Mar, Masao Ikeda-Saito, Kevin M. Smith, Catherine M. Bougault, Yi Dou, Kevin C. Langry
Publikováno v:
Journal of the American Chemical Society. 120:2113-2123
Solution 1D and 2D NMR, together with limited isotope labeling, have led to the assignment of the heme, axial His, and numerous heme contact residues in sperm whale, horse, and human deoxy myoglobi...
Autor:
Frank Dalichow, Wanda S. Smith, Jon B. Hauksson, David L. Budd, Gerd N. La Mar, Robert D. Johnson, Kevin C. Langry, Ian K. Morris, Nicolette L. Davis, Kevin M. Smith
Publikováno v:
Journal of the American Chemical Society. 115:3869-3876
The heme methyl resonances of sperm whale high-spin ferrous or deoxymyoglobin, Mb, have been assigned by a combination of 1 H and 2 H NMR of the protein reconstituted with specifically deuterated hemes. The complete methyl assignments were carried ou
Autor:
Bobba Rambabu, Kevin C. Langry
Publikováno v:
ChemInform. 30
Fiber optic chemical sensors and solid state devices are two versatile sensing technologies for detecting analytes in a host of media. Obvious differences distinguish these technologies: however, they share significant features and issues related to
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 22(4)
We present evidence of multivalent interactions between a single protein molecule and multiple carbohydrates at a pH where the protein can bind four ligands. The evidence is based not only on measurements of the force required to rupture the bonds fo
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 21(26)
We show with atomic force microscopy that thioctic acid, a spatially constrained system with two sulfur linkages to gold, is less stable to tensile stress than a thiolate with a single attachment to gold. The force required to remove the dithiolate-l
Autor:
Michael E. Colvin, Timothy V. Ratto, Huguette Albrecht, Aleksandr Noy, Todd Sulchek, Kevin C. Langry, Raymond W. Friddle, Edmond Y. Lau, Sally J. DeNardo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(46)
We used atomic force microscopy to measure the binding forces between Mucin1 (MUC1) peptide and a single-chain variable fragment (scFv) antibody selected from a scFv library screened against MUC1. This binding interaction is central to the design of