Diagnosis and testing for growth hormone deficiency across the ages: a global view of the accuracy, caveats, and cut-offs for diagnosis

Autor: Kevin C J Yuen, Gudmundur Johannsson, Ken K Y Ho, Bradley S Miller, Ignacio Bergada, Alan D Rogol

Publikováno v: Endocrine Connections, Vol 12, Iss 7, Pp 1-19 (2023)

Growth hormone deficiency (GHD) is a clinical syndrome that can manifest either as isolated or associated with additional pituitary hormone deficie ncies. Although diminished height velocity and short stature are useful and important clin ical marker

Externí odkaz: https://doaj.org/article/d648e617175949ae9a9510acf8088a7a

Sensitivity and specificity of the macimorelin test for diagnosis of AGHD

Autor: Jose M Garcia, Beverly M K Biller, Márta Korbonits, Vera Popovic, Anton Luger, Christian J Strasburger, Philippe Chanson, Ronald Swerdloff, Christina Wang, Rosa Rosanna Fleming, Fredric Cohen, Nicola Ammer, Gilbert Mueller, Nicky Kelepouris, Frank Strobl, Vlady Ostrow, Kevin C J Yuen

Publikováno v: Endocrine Connections, Vol 10, Iss 1, Pp 76-83 (2021)

Objective: The macimorelin test is approved for the diagnosis of adult growth hormone deficiency (AGHD) based on its efficacy vs the insulin tolerance t est (ITT). Macimorelin has a significant advantage over ITT in avoiding hypoglycemia. A nalyses w

Externí odkaz: https://doaj.org/article/cdaf660e6db34106934ef0032fb07ae0

Iatrogenic immunodeficiency-associated lymphoproliferative disorders of the central nervous system: a treatment paradox

Autor: Ramya Tadipatri, Chukwuyem Ekhator, Ram Narayan, Amir Azadi, Kevin C J Yuen, Jai Grewal, Ekokobe Fonkem

Publikováno v: Neuro-Oncology Practice. 10:169-175

Background Primary central nervous system lymphomas (PCNSLs) have historically had dismal survival rates until the advent of high-dose methotrexate (HD-MTX) based chemotherapy regimens. With increasing prevalence of autoimmune disease and development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8189e470a6261b6445cf9c45fab72895
https://doi.org/10.1093/nop/npac098

Hypothalamic-Pituitary and Other Endocrine Surveillance Among Childhood Cancer Survivors

Autor: Laura van Iersel, Renee L Mulder, Christian Denzer, Laurie E Cohen, Helen A Spoudeas, Lillian R Meacham, Elaine Sugden, Antoinette Y N Schouten-van Meeteren, Eelco W Hoving, Roger J Packer, Gregory T Armstrong, Sogol Mostoufi-Moab, Aline M Stades, Dannis van Vuurden, Geert O Janssens, Cécile Thomas-Teinturier, Robert D Murray, Natascia Di Iorgi, Sebastian J C M M Neggers, Joel Thompson, Andrew A Toogood, Helena Gleeson, Cecilia Follin, Edit Bardi, Lilibeth Torno, Briana Patterson, Vera Morsellino, Grit Sommer, Sarah C Clement, Deokumar Srivastava, Cecilie E Kiserud, Alberto Fernandez, Katrin Scheinemann, Sripriya Raman, Kevin C J Yuen, W Hamish Wallace, Louis S Constine, Roderick Skinner, Melissa M Hudson, Leontien C M Kremer, Wassim Chemaitilly, Hanneke M van Santen

Publikováno v: van Iersel, L, Mulder, R L, Denzer, C, Cohen, L E, Spoudeas, H A, Meacham, L R, Sugden, E, Schouten-van Meeteren, A Y N, Hoving, E W, Packer, R J, Armstrong, G T, Mostoufi-Moab, S, Stades, A M, van Vuurden, D, Janssens, G O, Thomas-Teinturier, C C, Murray, R D, di Iorgi, N, Neggers, S J C M M, Thompson, J, Toogood, A A, Gleeson, H, Follin, C, Bardi, E, Torno, L, Patterson, B, Morsellino, V, Sommer, G, Clement, S C, Srivastava, D, Kiserud, C E, Fernandez, A, Scheinemann, K, Raman, S, Yuen, K C J, Wallace, W H, Constine, L S, Skinner, R, Hudson, M M, Kremer, L C M, Chemaitilly, W & van Santen, H M 2022, ' Hypothalamic-Pituitary and Other Endocrine Surveillance Among Childhood Cancer Survivors ', Endocrine Reviews, vol. 43, no. 5, pp. 794-823 . https://doi.org/10.1210/endrev/bnab040
Endocrine Reviews, 43(5), 794-823. The Endocrine Society
Endocrine reviews, 43(5), 794-823. The Endocrine Society

Endocrine disorders in survivors of childhood, adolescent, and young adult (CAYA) cancers are associated with substantial adverse physical and psychosocial effects. To improve appropriate and timely endocrine screening and referral to a specialist, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c612346cb8130c767a55c462afd380
http://www.scopus.com/inward/record.url?scp=85135039606&partnerID=8YFLogxK

Diagnosis and testing for growth hormone deficiency (GHD) across the ages: a global view of the accuracy, caveats and cut-offs for diagnosis

Autor: Kevin C J Yuen, Gudmundur Johannsson, Ken K Y Ho, Bradley S. Miller, Ignacio Bergada, Alan D Rogol

Publikováno v: Endocrine Connections.

Growth hormone deficiency (GHD) is a clinical syndrome that can manifest either as isolated or associated with additional pituitary hormone deficiencies. Although diminished height velocity and short stature are useful and important clinical markers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75d70bea335fcab7f421f3404590ef8c
https://doi.org/10.1530/ec-22-0504