Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kevin C J Nixon"'
Autor:
Yang Yang, Jaeil Ahn, Nathan J. Edwards, Julius Benicky, Aaron M. Rozeboom, Bruce Davidson, Christina Karamboulas, Kevin C. J. Nixon, Laurie Ailles, Radoslav Goldman
Publikováno v:
Cancers, Vol 14, Iss 22, p 5553 (2022)
Pan-cancer analysis of TCGA and CPTAC (proteomics) data shows that SULF1 and SULF2 are oncogenic in a number of human malignancies and associated with poor survival outcomes. Our studies document a consistent upregulation of SULF1 and SULF2 in HNSC w
Externí odkaz:
https://doaj.org/article/4df26898ad314c08b57f7b9ab19acf71
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 11, Pp 3433-3446 (2018)
The formation and recall of long-term memory (LTM) requires neuron activity-induced gene expression. Transcriptome analysis has been used to identify genes that have altered expression after memory acquisition, however, we still have an incomplete pi
Externí odkaz:
https://doaj.org/article/709bea61135c4516ba1744a7b51523e1
Autor:
Parasvi S Patel, Arash Algouneh, Rehna Krishnan, John J Reynolds, Kevin C J Nixon, Jun Hao, Jihoon Lee, Yue Feng, Chehronai Fozil, Mia Stanic, Talya Yerlici, Peiran Su, Fraser Soares, Elisabeth Liedtke, Gil Prive, Gary D Baider, Miquel Angel Pujana, Karim Mekhail, Housheng Hansen He, Anne Hakem, Grant S Stewart, Razqallah Hakem
Publikováno v:
Nucleic Acids Research. 51:4341-4362
BRCA1 mutations are associated with increased breast and ovarian cancer risk. BRCA1-mutant tumors are high-grade, recurrent, and often become resistant to standard therapies. Herein, we performed a targeted CRISPR-Cas9 screen and identified MEPCE, a
Autor:
Melissa C. Chubak, Kevin C. J. Nixon, Max H. Stone, Nicholas Raun, Shelby L. Rice, Mohammed Sarikahya, Spencer G. Jones, Taylor A. Lyons, Taryn E. Jakub, Roslyn L. M. Mainland, Maria J. Knip, Tara N. Edwards, Jamie M. Kramer
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 3 (2019)
Technology has led to rapid progress in the identification of genes involved in neurodevelopmental disorders such as intellectual disability (ID), but our functional understanding of the causative genes is lagging. Here, we show that the SWI/SNF chro
Externí odkaz:
https://doaj.org/article/a1eef28601164a75ab26472f6bf35270
Autor:
Yang, Yang, Jaeil, Ahn, Nathan J, Edwards, Julius, Benicky, Aaron M, Rozeboom, Bruce, Davidson, Christina, Karamboulas, Kevin C J, Nixon, Laurie, Ailles, Radoslav, Goldman
Publikováno v:
Cancers. 14(22)
Pan-cancer analysis of TCGA and CPTAC (proteomics) data shows that SULF1 and SULF2 are oncogenic in a number of human malignancies and associated with poor survival outcomes. Our studies document a consistent upregulation of SULF1 and SULF2 in HNSC w
Autor:
Shane McKee, Christel Depienne, Diana Baralle, Ddd Study, Justine Rousseau, Philippe M. Campeau, Sophie Ehresmann, Naomichi Matsumoto, Solveig Heide, Max H. Stone, Hannah Titheradge, Alyssa Ritter, Kevin C J Nixon, Seiji Mizuno, Jamie M. Kramer, Delphine Héron, Noriko Miyake, Mohammed Sarikahya, Kosuke Izumi
Publikováno v:
American Journal of Human Genetics
American Journal of Human Genetics, 2019, 104 (4), pp.596-610. ⟨10.1016/j.ajhg.2019.02.001⟩
American Journal of Human Genetics, 2019, 104 (4), pp.596-610. ⟨10.1016/j.ajhg.2019.02.001⟩
Mutations in several genes encoding components of the SWI/SNF chromatin remodeling complex cause neurodevelopmental disorders (NDDs). Here, we report on 5 individuals with mutations in SMARCD1, presenting with developmental delay, intellectual disabi
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 8, Iss 11, Pp 3433-3446 (2018)
G3: Genes, Genomes, Genetics, Vol 8, Iss 11, Pp 3433-3446 (2018)
The formation and recall of long-term memory (LTM) requires neuron activity-induced gene expression. Transcriptome analysis has been used to identify genes that have altered expression after memory acquisition, however, we still have an incomplete pi
Autor:
Robert Gros, Jamie M. Kramer, Pierre E. Thibeault, Christina M.G. Vanderboor, Rithwik Ramachandran, Kevin C J Nixon
Publikováno v:
Physiology and Pharmacology Publications
Proteinase-Activated Receptors (PARs) are a four-member family of G-protein coupled receptors that are activated via proteolysis. PAR4 is a member of this family that is cleaved and activated by the serine proteinases such as thrombin, trypsin and ca
Autor:
Robert Gros, Rithwik Ramachandran, Christina M.G. Vanderboor, Pierre E. Thibeault, Kevin C J Nixon, Jamie M. Kramer
Proteinase-Activated Receptors (PARs) are a four-member family of G-protein coupled receptors that are activated via proteolysis. PAR4 is a member of this family that is cleaved and activated by serine proteinases such as thrombin, trypsin and cathep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a3e87fd6b3e95bc2dfc9299a305afe
Autor:
Tara N. Edwards, Spencer G. Jones, Maria J. Knip, Nicholas Raun, Max H. Stone, Shelby L. Rice, Mohammed Sarikahya, Melissa C. Chubak, Taryn E. Jakub, Kevin C J Nixon, Roslyn L. M. Mainland, Jamie M. Kramer, Taylor A. Lyons
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 12, Iss 3 (2019)
Disease Models & Mechanisms, Vol 12, Iss 3 (2019)
Technology has led to rapid progress in the identification of genes involved in neurodevelopmental disorders such as intellectual disability (ID), but our functional understanding of the causative genes is lagging. Here, we show that the SWI/SNF chro