Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Kevin C Chan"'
Autor:
Muneeb A Faiq, Trina Sengupta, Madhu Nath, Thirumurthy Velpandian, Daman Saluja, Rima Dada, Tanuj Dada, Kevin C Chan
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 1139-1146 (2023)
Central insulin resistance, the diminished cellular sensitivity to insulin in the brain, has been implicated in diabetes mellitus, Alzheimer’s disease and other neurological disorders. However, whether and how central insulin resistance plays a rol
Externí odkaz:
https://doaj.org/article/9a3186bb4fce4483b3c02044ddfc4d41
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 5, Pp 937-947 (2022)
Optic nerve health is essential for proper function of the visual system. However, the pathophysiology of certain neurodegenerative disease processes affecting the optic nerve, such as glaucoma, is not fully understood. Recently, it was hypothesized
Externí odkaz:
https://doaj.org/article/b7c3110b951544489080dd3f8f1348d7
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 11, Pp 1717-1719 (2015)
Externí odkaz:
https://doaj.org/article/89dd2e0f0ddf4e1c9ee99f3f37a28eef
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165169 (2016)
Visual function has been shown to deteriorate prior to the onset of retinopathy in some diabetic patients and experimental animal models. This suggests the involvement of the brain's visual system in the early stages of diabetes. In this study, we te
Externí odkaz:
https://doaj.org/article/07f09e43c1aa4abc8ec27738c18351f8
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144328 (2015)
Although pregnancy-induced hormonal changes have been shown to alter the brain at the neuronal level, the exact effects of pregnancy on brain at the tissue level remain unclear. In this study, diffusion tensor imaging (DTI) and resting-state function
Externí odkaz:
https://doaj.org/article/426145c9b9ea429d8f1b6385d247ee57
Autor:
Da Ma, Wenyu Deng, Zain Khera, Thajunnisa A. Sajitha, Xinlei Wang, Gadi Wollstein, Joel S. Schuman, Sieun Lee, Haolun Shi, Myeong Jin Ju, Joanne Matsubara, Mirza Faisal Beg, Marinko Sarunic, Rebecca M. Sappington, Kevin C. Chan
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Excitotoxicity from the impairment of glutamate uptake constitutes an important mechanism in neurodegenerative diseases such as Alzheimer’s, multiple sclerosis, and Parkinson's disease. Within the eye, excitotoxicity is thought to play a c
Externí odkaz:
https://doaj.org/article/94d8962b31084b0ca53d23684c47756a
Autor:
Giles Hamilton-Fletcher, Mingxin Liu, Diwei Sheng, Chen Feng, Todd E. Hudson, John-Ross Rizzo, Kevin C. Chan
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 54-58 (2024)
Goal: Distance information is highly requested in assistive smartphone Apps by people who are blind or low vision (PBLV). However, current techniques have not been evaluated systematically for accuracy and usability. Methods: We tested five smartphon
Externí odkaz:
https://doaj.org/article/fd22848451de465eb3d618634439b8fd
Autor:
Guangjun Xi, Jiaojie Hui, Zhijun Zhang, Shanshan Liu, Xiangrong Zhang, Gaojun Teng, Kevin C Chan, Ed X Wu, Binbin Nie, Baoci Shan, Lingjiang Li, Gavin P Reynolds
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28686 (2011)
It is generally accepted that cognitive processes, such as learning and memory, are affected in depression. The present study used a rat model of depression, chronic unpredictable mild stress (CUMS), to determine whether hippocampal volume and neuroc
Externí odkaz:
https://doaj.org/article/540be08a95264f569014e49332293e6d
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18914 (2011)
BACKGROUND: The superior colliculus (SC) and lateral geniculate nucleus (LGN) are important subcortical structures for vision. Much of our understanding of vision was obtained using invasive and small field of view (FOV) techniques. In this study, we
Externí odkaz:
https://doaj.org/article/4fa3efe7ac024af3966d774483b41af2
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Glaucoma is an age-related neurodegenerative disease of the visual system, affecting both the eye and the brain. Yet its underlying metabolic mechanisms and neurobehavioral relevance remain largely unclear. Here, using proton magnetic resona
Externí odkaz:
https://doaj.org/article/63176003fbdb47d19b1926c26e282a35