Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kevin Brower"'
Autor:
Marcus Fiadeiro, Brad Bouchard, Nihal Tugcu, Rohan Patil, Tarl Vetter, Jason Walther, Kevin Brower, Emily Davenport, Chad Varner, Michael Coolbaugh
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 118(9)
There has been increasing momentum recently in the biopharmaceutical industry to transition from traditional batch processes to next-generation integrated and continuous biomanufacturing. This transition from batch to continuous is expected to offer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b964f5405614bdd058e56d009615880d
https://pubmed.ncbi.nlm.nih.gov/33410159
https://pubmed.ncbi.nlm.nih.gov/33410159
Autor:
Kevin Brower, Rohan A. Patil, Konstantin Konstantinov, Veena Warikoo, Chad Varner, Rahul Godawat
Publikováno v:
Biotechnology journalREFERENCES. 16(4)
An important consideration for integrated continuous biomanufacturing is that the downstream chromatography steps integrated with the bioreactor should maintain a low bioburden state throughout the entire duration of the operation. One potential stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd93c9b5886227b3936cbaf945cd5fe
https://pubmed.ncbi.nlm.nih.gov/33314754
https://pubmed.ncbi.nlm.nih.gov/33314754
Autor:
Chris Hwang, Jason Walther, Jiuyi Lu, Jean McLarty, Myles Hollenbach, Kevin Brower, Marcella Yu
Publikováno v:
Biotechnology journal. 14(2)
In this study, the authors compared the impacts of fed-batch and perfusion platforms on process and product attributes for IgG1- and IgG4-producing cell lines. A "plug-and-play" approach is applied to both platforms at bench scale, using commercially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a4e32e9b50f315c6361628c3de6de0
https://pubmed.ncbi.nlm.nih.gov/29851298
https://pubmed.ncbi.nlm.nih.gov/29851298
Publikováno v:
Biotechnology Journal. 7:1496-1508
Integrated and continuous processing of recombinant proteins offers several advantages over batch or semi-batch processing used traditionally in the biotechnology industry. This paper presents a theoretical and practical approach for designing a peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666cf8dd1db29c0f368fc37fc66e4f17
https://doi.org/10.1002/biot.201200068
https://doi.org/10.1002/biot.201200068