Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Kevin Braeckmans"'
Autor:
Waqar Saleem, Nathan Carpentier, Charlotte Hinnekens, Dayoung Oh, Sandra Van Vlierberghe, Kevin Braeckmans, Hans Nauwynck
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-16 (2024)
Abstract Transmissible gastroenteritis virus (TGEV) causes high mortality in young piglets (
Externí odkaz:
https://doaj.org/article/3df4a10cc4bc41a1ba15044dd196635a
Autor:
Laurens Léger, Chloë De Clercq, Jeffrey Aalders, Kiara Van Acker-Verberckt, Kevin Braeckmans, Jolanda van Hengel
Publikováno v:
MethodsX, Vol 12, Iss , Pp 102548- (2024)
Human induced pluripotent stem cell-derived cardiomyocytes (iPSCCMs) are promising candidates for disease modeling and therapeutic purposes, however, non-viral intracellular delivery in these cells remains challenging. Gold nanoparticle (AuNP)-sen
Externí odkaz:
https://doaj.org/article/bc69f80ebb354e01a4e2b5c3c9d3de55
Autor:
Majid Layachi, Anthony Treizebré, Laurent Hay, David Gilbert, Jean Pesez, Quentin D’Acremont, Kevin Braeckmans, Quentin Thommen, Emmanuel Courtade
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Intracellular drug delivery is at the heart of many diagnosis procedures and a key step in gene therapy. Research has been conducted to bypass cell barriers for controlled intracellular drug release and made consistent progress. However, sta
Externí odkaz:
https://doaj.org/article/837cf83d3416450ebc05c4fb6ae097c0
Autor:
Juan C. Fraire, Elnaz Shaabani, Maryam Sharifiaghdam, Matthias Rombaut, Charlotte Hinnekens, Dawei Hua, Jana Ramon, Laurens Raes, Eduardo Bolea-Fernandez, Toon Brans, Frank Vanhaecke, Peter Borghgraef, Chaobo Huang, Félix Sauvage, Tamara Vanhaecke, Joery De Kock, Ranhua Xiong, Stefaan De Smedt, Kevin Braeckmans
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Ballistic delivery with micro/nano-particles has been successfully used to transfect plant cells, however, has failed in mammalian cells due to toxic effects. Here, the authors report on a self-assembled nano-ballistic delivery system for the deliver
Externí odkaz:
https://doaj.org/article/77d1d8da1f724b5b9fd372d74134f2d8
Publikováno v:
Nano Convergence, Vol 9, Iss 1, Pp 1-17 (2022)
Abstract Delivery of nanomaterials into cells is of interest for fundamental cell biological research as well as for therapeutic and diagnostic purposes. One way of doing so is by physically disrupting the plasma membrane (PM). Several methods that e
Externí odkaz:
https://doaj.org/article/b2263ab6d7f747f9a907728938564ff0
Autor:
Laurens Raes, Melissa Pille, Aranit Harizaj, Glenn Goetgeluk, Jelter Van Hoeck, Stephan Stremersch, Juan C. Fraire, Toon Brans, Olivier Gerrit de Jong, Roel Maas-Bakker, Enrico Mastrobattista, Pieter Vader, Stefaan C. De Smedt, Bart Vandekerckhove, Koen Raemdonck, Kevin Braeckmans
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 696-707 (2021)
The CRISPR-Cas9 technology represents a powerful tool for genome engineering in eukaryotic cells, advancing both fundamental research and therapeutic strategies. Despite the enormous potential of the technology, efficient and direct intracellular del
Externí odkaz:
https://doaj.org/article/d83a80530b204562bf8701e1aa7bfddd
Autor:
Laurens Raes, Stephan Stremersch, Juan C. Fraire, Toon Brans, Glenn Goetgeluk, Stijn De Munter, Lien Van Hoecke, Rein Verbeke, Jelter Van Hoeck, Ranhua Xiong, Xavier Saelens, Bart Vandekerckhove, Stefaan De Smedt, Koen Raemdonck, Kevin Braeckmans
Publikováno v:
Nano-Micro Letters, Vol 12, Iss 1, Pp 1-17 (2020)
Abstract Efficient and safe cell engineering by transfection of nucleic acids remains one of the long-standing hurdles for fundamental biomedical research and many new therapeutic applications, such as CAR T cell-based therapies. mRNA has recently ga
Externí odkaz:
https://doaj.org/article/543a96ad06524b4f9271212ffb59401e
Autor:
Heyang Zhang, Jeroen Bussmann, Florian H. Huhnke, Joke Devoldere, An‐Katrien Minnaert, Wim Jiskoot, Friedhelm Serwane, Joachim Spatz, Magnus Röding, Stefaan C. De Smedt, Kevin Braeckmans, Katrien Remaut
Publikováno v:
Advanced Science, Vol 9, Iss 4, Pp n/a-n/a (2022)
Abstract Liposomes can efficiently deliver messenger RNA (mRNA) into cells. When mRNA cocktails encoding different proteins are needed, a considerable challenge is to efficiently deliver all mRNAs into the cytosol of each individual cell. In this wor
Externí odkaz:
https://doaj.org/article/836eb56c915b40afa530d03660979760
Autor:
Kaat De Clerck, Geraldine Accou, Félix Sauvage, Kevin Braeckmans, Stefaan C. De Smedt, Katrien Remaut, Karen Peynshaert
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1716 (2022)
The inner limiting membrane (ILM) represents a major bottleneck hampering efficient drug delivery to the retina after intravitreal injection. To overcome this barrier, we intend to perforate the ILM by use of a light-based approach which relies on th
Externí odkaz:
https://doaj.org/article/cf040bed09cd49c3ba48e33ada5d456b
Autor:
Maryam Sharifiaghdam, Elnaz Shaabani, Zeynab Sharifiaghdam, Herlinde De Keersmaecker, Riet De Rycke, Stefaan De Smedt, Reza Faridi-Majidi, Kevin Braeckmans, Juan C. Fraire
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Nanotechnology has made an important contribution to oncology in recent years, especially for drug delivery. While many different nano-delivery systems have been suggested for cancer therapy, selenium nanoparticles (SeNPs) are particularly promising
Externí odkaz:
https://doaj.org/article/42bb1b9f3e2d48a1badbe7a54956b04e