Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kevin B. Turner"'
Autor:
Joshua J Sims, Jenny A Greig, Kristofer T Michalson, Sharon Lian, R Alexander Martino, Rosemary Meggersee, Kevin B Turner, Kalyani Nambiar, Cecilia Dyer, Christian Hinderer, Makoto Horiuchi, Hanying Yan, Xin Huang, Shu-Jen Chen, James M Wilson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009544 (2021)
SARS-CoV-2 variants have emerged with enhanced pathogenicity and transmissibility, and escape from pre-existing immunity, suggesting first-generation vaccines and monoclonal antibodies may now be less effective. Here we present an approach for preven
Externí odkaz:
https://doaj.org/article/1456eae8f81744b0b130542e55e5bbc3
Autor:
Chia-Wei Yang, Kevin B. Turner
Publikováno v:
Jung Journal. 15:90-102
C. G. Jung carved a memorial stone in Chinese for Toni Wolff after her death in 1953. Why he carved a memorial stone in Chinese for his “spiritual wife” is unknown. Efforts at deciphering Jung’s in...
Autor:
Kevin B. Turner
Part travelogue, part experiential spiritual memoir, Kevin Turner takes us to visit with authentic shamans in the steppes and urban centers of modern-day Mongolia. Along the way, the author, a practicing shaman himself, tells of spontaneous medical d
Probing Anomalous Structural Features in Polypurine Tract-Containing RNA−DNA Hybrids with Neomycin B
Autor:
Kevin B. Turner, Robert G. Brinson, Stuart F.J. Le Grice, John P. Marino, Hye Young Yi-Brunozzi, Daniele Fabris
Publikováno v:
Biochemistry. 48:6988-6997
During (-)-strand DNA synthesis in retroviruses and Saccharomyces cerevisiae LTR retrotransposons, a purine rich region of the RNA template, known as the polypurine tract (PPT), is resistant to RNase H-mediated hydrolysis and subsequently serves as a
Publikováno v:
Biopolymers. 91:283-296
The nature of specific RNA-RNA and protein-RNA interactions involved in the process of genome dimerization and isomerization in HIV-1, which is mediated in vitro by the stemloop 1 (SL1) of the packaging signal and by the nucleocapsid (NC) domain of t
Publikováno v:
Journal of the American Chemical Society. 130:13353-13363
A rare example of ion/ion reaction between species of like polarity was shown to take place during the transfer of metal cations from nucleic acid substrates to chelating agents in the gas phase. Gaseous anionic reactants were generated from separate
Autor:
Jennifer T. Miller, Stuart F. J. Le Grice, Hye Young Yi-Brunozzi, Daniele Fabris, Jason W. Rausch, John P. Marino, Kevin B. Turner, Robert G. Brinson
Publikováno v:
Nucleic Acids Research
The interactions of archetypical nucleic acid ligands with the HIV-1 polypurine tract (PPT) RNA:DNA hybrid, as well as analogous DNA:DNA, RNA:RNA and swapped hybrid substrates, were used to probe structural features of the PPT that contribute to its
Autor:
Loryn R. Keating, Veronika A. Szalai, Sarah Melchoir, Ryan T. Grimes, Sarah E. Evans, Miguel Angel Mendez, Kevin B. Turner
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 12:1235-1249
Nucleic acids that contain multiple sequential guanines assemble into guanine quadruplexes (G-quadruplexes). Drugs that induce or stabilize G-quadruplexes are of interest because of their potential use as therapeutics. Previously, we reported on the
Publikováno v:
Journal of the American Society for Mass Spectrometry. 17:1402-1411
The binding modes and structural determinants of the noncovalent complexes formed by aminoglycoside antibiotics with conserved domains of the HIV-1 packaging signal (Psi-RNA) were investigated using electrospray ionization (ESI) Fourier transform mas
Publikováno v:
Nucleic Acids Research
Disrupting the interactions between human immunodeficiency virus type 1 (HIV-1) nucleocapsid (NC) protein and structural elements of the packaging signal (Psi-RNA) could constitute an ideal strategy to inhibit the functions of this region of the geno