Zobrazeno 1 - 9
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pro vyhledávání: '"Kevin B. Passi"'
Supplementary Table 1 describes the parental strains and mutations used to generate attenuated ST strains.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24cf134948b1439ffff79bf9e7496b6
https://doi.org/10.1158/1535-7163.22521696.v1
https://doi.org/10.1158/1535-7163.22521696.v1
Supplementary Figure 1 describes BHs expression in uninduced ST strains as well as the predicted localization of BHs. Viability of bHs-expressing ST strains is analyzed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd83218aa5660badf38f9ce1859f270
https://doi.org/10.1158/1535-7163.22521708.v1
https://doi.org/10.1158/1535-7163.22521708.v1
Supplementary Figure 2 describes the ability of X8768-BHs to degrade HA from fixed human PC-3 prostate cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58abaa774f3613c06c3724df0a56b824
https://doi.org/10.1158/1535-7163.22521705
https://doi.org/10.1158/1535-7163.22521705
Supplementary Figure 3 describes the ability of X8768 expressing bacterial luciferase to colonize tumors and peripheral tissues, as well as how HA degradation affects vasculature in PANC-1 tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f45c63d49420eb6a8098ea2e27e9638
https://doi.org/10.1158/1535-7163.22521702.v1
https://doi.org/10.1158/1535-7163.22521702.v1
Supplementary Figure 4 shows that treatment with X8768-BHs does not degrade HA is non-tumor tissues, and does not affaect total cellular content of tumor tissue where HA was degraded.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5b95c6a78dc9c8c7d3d6239af2e819
https://doi.org/10.1158/1535-7163.22521699.v1
https://doi.org/10.1158/1535-7163.22521699.v1
Publikováno v:
Molecular Cancer Therapeutics. 19:706-716
In pancreatic ductal adenocarcinoma (PDAC), the extracellular matrix (ECM) surrounding cancer cells forms a barrier that often limits the ability of chemotherapeutic drugs and cytotoxic immune subsets to penetrate and eliminate tumors. The dense stro
Autor:
Edith Zuniga, Kevin B Passi, Cari A Young, Edwin R. Manuel, Vic Zamloot, Lukas J Sobocinski, Bruce R. Blazar, Nancy D. Ebelt
Publikováno v:
Cancers
Volume 13
Issue 14
Cancers, Vol 13, Iss 3565, p 3565 (2021)
Volume 13
Issue 14
Cancers, Vol 13, Iss 3565, p 3565 (2021)
Therapeutic resistance in pancreatic ductal adenocarcinoma (PDAC) can be attributed, in part, to a dense extracellular matrix containing excessive collagen deposition. Here, we describe a novel Salmonella typhimurium (ST) vector expressing the bacter
Autor:
Nancy D, Ebelt, Vic, Zamloot, Edith, Zuniga, Kevin B, Passi, Lukas J, Sobocinski, Cari A, Young, Bruce R, Blazar, Edwin R, Manuel
Publikováno v:
Cancers
Simple Summary The deposition of fibrotic tissue within pancreatic tumors acts as a physical barrier to therapeutic treatment. Collagen constitutes a large part of this barrier and serves as an ideal target to improve delivery and efficacy of anti-ca
Publikováno v:
Mol Cancer Ther
In pancreatic ductal adenocarcinoma (PDAC), the extracellular matrix (ECM) surrounding cancer cells forms a barrier that often limits the ability of chemotherapeutic drugs and cytotoxic immune subsets to penetrate and eliminate tumors. The dense stro