Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kevin B. L. Lin"'
Autor:
Katharina Rothe, Hanyang Lin, Hui Mi Wang, Mehrnoush Malekesmaeili, Amy Leung, Xiaoyan Jiang, Kevin B. L. Lin, Ryan R. Brinkman, Donna L. Forrest, Sharon M. Gorski
Publikováno v:
Blood. 123:3622-3634
Previous studies demonstrated that imatinib mesylate (IM) induces autophagy in chronic myeloid leukemia (CML) and that this process is critical to cell survival upon therapy. However, it is not known if the autophagic process differs at basal levels
Autor:
Amy Leung, Kevin B. L. Lin, Hanyang Lin, Xiaoyan Jiang, Katharina Rothe, Donna L. Forrest, Sharon M. Gorski
Publikováno v:
Blood. 120:1662-1662
Abstract 1662 Chronic myeloid leukemia (CML) stem cells are biologically insensitive to ABL tyrosine kinase inhibitor (TKI) monotherapy and are genetically unstable and rapidly generate imatinib (IM)-resistant mutants in vivo and in vitro. Therefore,
Publikováno v:
Cell Adhesion & Migration; Jul2010, Vol. 4 Issue 3, p327-332, 6p