Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Kevin B. Jones"'
Autor:
Amir Pozner, Li Li, Shiv Prakash Verma, Shuxin Wang, Jared J. Barrott, Mary L. Nelson, Jamie S. E. Yu, Gian Luca Negri, Shane Colborne, Christopher S. Hughes, Ju-Fen Zhu, Sydney L. Lambert, Lara S. Carroll, Kyllie Smith-Fry, Michael G. Stewart, Sarmishta Kannan, Bodrie Jensen, Cini M. John, Saif Sikdar, Hongrui Liu, Ngoc Ha Dang, Jennifer Bourdage, Jinxiu Li, Jeffery M. Vahrenkamp, Katelyn L. Mortenson, John S. Groundland, Rosanna Wustrack, Donna L. Senger, Franz J. Zemp, Douglas J. Mahoney, Jason Gertz, Xiaoyang Zhang, Alexander J. Lazar, Martin Hirst, Gregg B. Morin, Torsten O. Nielsen, Peter S. Shen, Kevin B. Jones
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The t(X,17) chromosomal translocation, generating the ASPSCR1::TFE3 fusion oncoprotein, is the singular genetic driver of alveolar soft part sarcoma (ASPS) and some Xp11-rearranged renal cell carcinomas (RCCs), frustrating efforts to identif
Externí odkaz:
https://doaj.org/article/22b004d19a254382bdb0a79d65c8bcf2
Autor:
Ryan D. Kraus, MD, Christopher R. Weil, MD, MS, Stacey Wells, MD, Jonathan D. Tward, MD, PhD, John S. Groundland, MD, MS, Kevin B. Jones, MD, Donald M. Cannon, MD
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 2, Pp 100795- (2022)
Purpose: Patients who undergo surgical stabilization for impending or pathologic fractures secondary to metastasis are often treated with radiation therapy to the involved site. We sought to retrospectively analyze outcomes from single versus multifr
Externí odkaz:
https://doaj.org/article/6389d6f6b69f4470904f9e21d65dca7f
Autor:
Nikita Patel, Juehong Wang, Kumiko Shiozawa, Kevin B. Jones, Yanfeng Zhang, Jeremy W. Prokop, George G. Davenport, Naoe T. Nihira, Zhenyue Hao, Derek Wong, Laurel Brandsmeier, Sarah K. Meadows, Arthur V. Sampaio, Ryan Vander Werff, Makoto Endo, Mario R. Capecchi, Kelly M. McNagny, Tak W. Mak, Torsten O. Nielsen, T. Michael Underhill, Richard M. Myers, Tadashi Kondo, Le Su
Publikováno v:
iScience, Vol 13, Iss , Pp 43-54 (2019)
Summary: Histone deacetylases (HDACs) are promising targets for cancer therapy, although their individual actions remain incompletely understood. Here, we identify a role for HDAC2 in the regulation of MDM2 acetylation at previously uncharacterized l
Externí odkaz:
https://doaj.org/article/86168b789a6f460780d4cbfa71bccd3c
Autor:
Logan Horne, Frank R. Avilucea, Huifeng Jin, Jared J. Barrott, Kyllie Smith-Fry, Yanliang Wang, Bang H. Hoang, Kevin B. Jones
Publikováno v:
Translational Oncology, Vol 9, Iss 5, Pp 438-444 (2016)
Previous reports document expression of low-density lipoprotein receptor-related protein 5 (LRP5) in osteosarcoma (OS) tissue. Expression of this Wnt receptor correlated with metastatic disease and poor disease-free survival. Forced expression of dom
Externí odkaz:
https://doaj.org/article/0d8d7a4935f347c2b74b4afa00e7ffb9
Autor:
Holly Lynn Spraker, Shawn ePrice, Aashi eChaturvedi, Joshua D. Schiffman, Kevin B. Jones, Stephen eLessnick, Mary eBeckerle, R. Lor eRandall
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
Ewing sarcoma (ES) is the second most common bone tumor affecting primarily adolescents and young adults. Despite recent advances in biological understanding, intensification of chemotherapeutic treatments, and progress in local control with surgery
Externí odkaz:
https://doaj.org/article/51071649c1fc4ffb971c34019e5bbda3
Publikováno v:
Sarcoma, Vol 2012 (2012)
Extra-abdominal desmoid tumors are a significant cause of morbidity in patients with familial adenomatous polyposis syndrome. Understanding of the basic biology and natural history of these tumors has increased substantially over the past decade. Acc
Externí odkaz:
https://doaj.org/article/e49bb2482ebd48648861a3f2d781701b
Autor:
George T. Calvert, R. Lor Randall, Kevin B. Jones, Lisa Cannon-Albright, Stephen Lessnick, Joshua D. Schiffman
Publikováno v:
Sarcoma, Vol 2012 (2012)
Osteosarcoma is the most common primary malignancy of bone. Most cases are sporadic without a known genetic or environmental cause. Heritable genetic predisposition syndromes are associated with a small percentage of osteosarcomas. Study of these rar
Externí odkaz:
https://doaj.org/article/8915523b32f547708db413c617630754
Publikováno v:
Sarcoma, Vol 2011 (2011)
Ewing's sarcoma is the second most common bone malignancy affecting children and young adults. The prognosis is especially poor in metastatic or relapsed disease. The cell of origin remains elusive, but the EWS-FLI1 fusion oncoprotein is present in t
Externí odkaz:
https://doaj.org/article/3117e8d0f405462484d4c1015a26a32b
Publikováno v:
Sarcoma, Vol 2011 (2011)
One important mechanism by which cancer cells parasitize their host is by escaping apoptosis. Thus, selectively facilitating apoptosis is a therapeutic mechanism by which oncotherapy may prove highly advantageous. One major apoptotic pathway is media
Externí odkaz:
https://doaj.org/article/835964e7caf34ef99aa15f30c2b45f2f
Autor:
Kevin B. Jones
Publikováno v:
Sarcoma, Vol 2011 (2011)
Osteosarcoma remains a deadly malignancy afflicting adolescents and young adults. The lack of a precursor and the panoply of genetic aberrations present in identified osteosarcomas makes study of its initiation difficult. A number of candidate hypoth
Externí odkaz:
https://doaj.org/article/cd23501a473b4e4abe7e5e087420d859