Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Kevin B. Bacon"'
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154874 (2016)
Idiopathic pulmonary fibrosis (IPF) is a progressive, debilitating disease for which two medications, pirfenidone and nintedanib, have only recently been approved for treatment. The cytokine TGF-β has been shown to be a central mediator in the disea
Externí odkaz:
https://doaj.org/article/38055d636c7843c8825acf55b31e768b
Autor:
Stefen A Boehme, Karin Franz-Bacon, John Ludka, Danielle N DiTirro, Tai Wei Ly, Kevin B Bacon
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167169 (2016)
Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung inflammation resulting in a progressive decline in lung function whose principle cause is cigarette smoke. MAP3K19 is a novel kinase expressed pre
Externí odkaz:
https://doaj.org/article/95344ca64b304d05af4f2cf8aefbe57d
Autor:
Milena S. Espindola, David M. Habiel, Rohan Narayanan, Kevin B. Bacon, Cory M. Hogaboam, Isabelle Jones, Stefen A. Boehme, Ana Lucia Coelho, Tai Wei Ly
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Idiopathic Pulmonary Fibrosis (IPF) is a disease with a devastating prognosis characterized by unrelenting lung scarring. Aberrant activation of lung fibroblasts is a key feature of this disease, yet the key pathways responsible for this are poorly u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f05e1e46e899a82ddb209b3a9cc4c6
http://link.springer.com/article/10.1038/s41598-019-56393-z
http://link.springer.com/article/10.1038/s41598-019-56393-z
Autor:
Michitaka Shichijo, Shinichi Kondo, Mina Ishimori, Shinichi Watanabe, Heidi Helin, Tsugiko Yamasaki, Mary E Stevens, Florian Gantner, Kevin B Bacon
Publikováno v:
Allergology International, Vol 55, Iss 3, Pp 271-278 (2006)
Background: To investigate the functional role of protease activated receptor (PAR) -2 in T lymphocytes, we analyzed TCR-mediated inflammatory cytokine production using PAR-2 deficient (KO) and wild type (WT) mice. Methods: Production of serum IgE an
Externí odkaz:
https://doaj.org/article/39843e3c18dd46c38ca10ccc9dfbf58e
Autor:
T J Schall, Gary Hardiman, W Wang, Devora L. Rossi, Albert Zlotnik, J F Bazan, K Soo, Kevin B. Bacon, David R. Greaves
Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key role in inflammatory and infectious diseases such as AIDS. All chemokines studied so far are secreted proteins of relative molecular mass approximately 7K-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e54a6c2f721e146d0007e94383c4bc
https://doi.org/10.1038/385640a0
https://doi.org/10.1038/385640a0
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0154874 (2016)
PLoS ONE, Vol 11, Iss 5, p e0154874 (2016)
Idiopathic pulmonary fibrosis (IPF) is a progressive, debilitating disease for which two medications, pirfenidone and nintedanib, have only recently been approved for treatment. The cytokine TGF-β has been shown to be a central mediator in the disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6eb3b243642ad58a61a8ebd029da27
http://europepmc.org/articles/PMC4856290
http://europepmc.org/articles/PMC4856290
Publikováno v:
Journal of Thoracic Oncology. 12:S1152-S1153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd26cab149a1bd3a927984d3b1d3b9eb
https://doi.org/10.1016/j.jtho.2016.11.1620
https://doi.org/10.1016/j.jtho.2016.11.1620
Autor:
Markus H. Gräler, Galya Vassileva, Sven Golfier, Sergio A. Lira, Tobias Schulze, Yasuhisa Endo, Kevin B. Bacon, Susan J. Abbondanzo, Tomomi Takeuchi, Martin Lipp, Shinichi Kondo, Maria T. Wiekowski, Ariel H. Achtman, Elisabeth Kremmer
Publikováno v:
The FASEB Journal. 24:4701-4710
Megakaryocytes, which mature from hematopoietic progenitors in the bone marrow, further differentiate by reorganizing their cytoplasm into long proplatelet extensions that release platelets into the circulation. The molecular mechanisms underlying th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbf4dd1629f6719afb6e7db791708bb
https://doi.org/10.1096/fj.09-141473
https://doi.org/10.1096/fj.09-141473
Autor:
Kevin B. Bacon, Edward P. Chen, Gary Hardiman, Tai Wei Ly, Stefen A. Boehme, Karin Franz-Bacon, Roman Sasik, L. James Sprague
Publikováno v:
International Immunology. 21:81-93
A FITC-induced allergic contact hypersensitivity model was used to investigate the role that the prostaglandin D(2) receptor-chemoattractant receptor-homologous molecule expressed on T(h)2 cells (CRTH2) plays in modulating cutaneous inflammation. Our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b81fde694fbc105bde3284e8ce729a6
https://doi.org/10.1093/intimm/dxn127
https://doi.org/10.1093/intimm/dxn127
Autor:
Marc Stadler, Kevin B. Bacon, Peter Reinemer, Hartwig Müller, Florian Gantner, Hans-Volker Tichy, Jens Bitzer, Jordi Benet-Buchholz, Anke Mayer-Bartschmid
Publikováno v:
Journal of Natural Products. 70:246-252
The cinnabaramides A-G (1-7) were isolated from a terrestrial strain of Streptomyces as potent and selective inhibitors of the human 20S proteasome. Their chemical and biological properties resemble those of salinosporamide A, a recently identified l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62f2fb500cc350fa8fe2563d20e326b
https://doi.org/10.1021/np060162u
https://doi.org/10.1021/np060162u