Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Kevin B Urdahl"'
Autor:
Courtney R Plumlee, Holly W Barrett, Danica E Shao, Katie A Lien, Lauren M Cross, Sara B Cohen, Paul T Edlefsen, Kevin B Urdahl
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011825 (2023)
Despite widespread immunization with Bacille-Calmette-Guérin (BCG), the only currently licensed tuberculosis (TB) vaccine, TB remains a leading cause of mortality globally. There are many TB vaccine candidates in the developmental pipeline, but the
Externí odkaz:
https://doaj.org/article/312bbc85b8014851a259ff53ee61ece1
Autor:
Amanda J Martinot, Eryn Blass, Jingyou Yu, Malika Aid, Shant H Mahrokhian, Sara B Cohen, Courtney R Plumlee, Rafael A Larocca, Noman Siddiqi, Shoko Wakabayashi, Michelle Gardner, Rebecca Audette, Anne Devorak, Kevin B Urdahl, Eric J Rubin, Dan H Barouch
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009096 (2020)
Bacille Calmette-Guerin (BCG), an attenuated whole cell vaccine based on Mycobacterium bovis, is the only licensed vaccine against Mycobacterium tuberculosis (Mtb), but its efficacy is suboptimal and it fails to protect against pulmonary tuberculosis
Externí odkaz:
https://doaj.org/article/5618c6f81d13453f82e4f2111c2896a8
Autor:
Johannes Nemeth, Gregory S Olson, Alissa C Rothchild, Ana N Jahn, Dat Mai, Fergal J Duffy, Jared L Delahaye, Sanjay Srivatsan, Courtney R Plumlee, Kevin B Urdahl, Elizabeth S Gold, Alan Aderem, Alan H Diercks
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008655 (2020)
Progress in tuberculosis vaccine development is hampered by an incomplete understanding of the immune mechanisms that protect against infection with Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis. Although the M72/ASOE1 trial y
Externí odkaz:
https://doaj.org/article/8b125e515468469890da614482c96ca1
Autor:
Caleb R. Stoltzfus, Jakub Filipek, Benjamin H. Gern, Brandy E. Olin, Joseph M. Leal, Yajun Wu, Miranda R. Lyons-Cohen, Jessica Y. Huang, Clarissa L. Paz-Stoltzfus, Courtney R. Plumlee, Thomas Pöschinger, Kevin B. Urdahl, Mario Perro, Michael Y. Gerner
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Recently developed approaches for highly multiplexed imaging have revealed complex patterns of cellular positioning and cell-cell interactions with important roles in both cellular- and tissue-level physiology. However, tools to quantitative
Externí odkaz:
https://doaj.org/article/1df5a2d1e3124838b0964fff24a70671
Autor:
Sambasivan Venkatasubramanian, Robyn Pryor, Courtney Plumlee, Sarah B. Cohen, Jason D. Simmons, Alexander J. Warr, Andrew D. Graustein, Aparajita Saha, Thomas R. Hawn, Kevin B. Urdahl, Javeed A. Shah
Publikováno v:
The Journal of Immunology. 209:435-445
TOLLIP is a central regulator of multiple innate immune signaling pathways, including TLR2, TLR4, IL-1R, and STING. Human TOLLIP deficiency, regulated by single-nucleotide polymorphism rs5743854, is associated with increased tuberculosis risk and dim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b73c2a4e873808a75a9fc3690a10a0d
https://doi.org/10.4049/jimmunol.2200030
https://doi.org/10.4049/jimmunol.2200030
Autor:
Samuel J. Vidal, Daniel Sellers, Jingyou Yu, Shoko Wakabayashi, Jaimie Sixsmith, Malika Aid, Julia Barrett, Sage F. Stevens, Xiaowen Liu, Wenjun Li, Courtney R. Plumlee, Kevin B. Urdahl, Amanda J. Martinot, Dan H. Barouch
Bacillus Calmette–Guérin (BCG) remains the only clinically approved tuberculosis (TB) vaccine despite limited efficacy. Preclinical studies of next generation TB vaccines have typically used a murine aerosol challenge model that employs a high sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c49746640785b2b3dec277ce287112
https://doi.org/10.1101/2023.03.17.533226
https://doi.org/10.1101/2023.03.17.533226
Autor:
Donald D. Nyangahu, Courtney R. Plumlee, Bryan P. Brown, Colin Feng, Enock Havyarimana, Sara B. Cohen, Kevin B. Urdahl, Heather B. Jaspan
Publikováno v:
Microbiology Spectrum. 10
Whether antibiotic treatment during gestation impacts T cell immunity to vaccination in offspring is unexplored. Dams treated with polymyxin B (PMB) during gestation (Mg) displayed altered microbial communities prior to delivery compared to control d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e19c3bff2135cc4b81ea51be97ff858
https://doi.org/10.1128/spectrum.02491-22
https://doi.org/10.1128/spectrum.02491-22
Autor:
Samuel J. Vidal, Daniel Sellers, Jingyou Yu, Shoko Wakabayashi, Jaimie Sixsmith, Malika Aid, Julia Barrett, Sage F. Stevens, Xiaowen Liu, Wenjun Li, Courtney R. Plumlee, Kevin B. Urdahl, Amanda J. Martinot, Dan H. Barouch
Publikováno v:
iScience. :106963
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aa44da78765c53ab5a0b541cf0ea1df
https://doi.org/10.1016/j.isci.2023.106963
https://doi.org/10.1016/j.isci.2023.106963
Autor:
Melanie A. Gasper, Nicholas Lejarcegui, Heather B. Jaspan, Helen Horton, Enock Havyarimana, Soren Gantt, Ana Gervassi, Elvis B. Kidzeru, Paul T. Edlefsen, Danica Shao, Kevin B. Urdahl
Publikováno v:
J Leukoc Biol
The role of Myeloid-Derived Suppressor Cells (MDSC) in infant immune ontogeny is unknown. Here, we evaluated MDSC frequency and relationship with infant vaccine responses throughout the first year of life in a prospective cohort study. Ninety-one Sou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a4f281eac2a28f00b3daafb7664289
https://doi.org/10.1002/jlb.5a0420-281r
https://doi.org/10.1002/jlb.5a0420-281r
Autor:
Andriёtte M. Hiemstra, Candice E. MacDonald, Ilana C. van Rensburg, Kim Stanley, Elizna Maasdorp, Shirley Mc Anda, Susanne Tönsing, Jane Alexandra Shaw, Gerard Tromp, Gian D. van der Spuy, Kevin B. Urdahl, David M. Lewinsohn, Helena Kuivaniemi, Nelita Du Plessis, Stephanus T. Malherbe, Gerhard Walzl
Publikováno v:
BMC Infectious Diseases. 22
Background Natural immunity against Mycobacterium tuberculosis exists, and > 90% of those infected remain disease-free. Innate and adaptive immune responses required to mediate such protection against tuberculosis (TB) are, however, poorly understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1984855b3c0527abd2384d570f789c
https://doi.org/10.1186/s12879-022-07349-8
https://doi.org/10.1186/s12879-022-07349-8