Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Kevin B, Kim"'
Autor:
Philippe D. Gascard, Xianhong Wang, Mehdi Nosrati, Kevin B. Kim, Mohammed Kashani-Sabet, Thea D. Tlsty, Stanley P. Leong, Mary J. C. Hendrix
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Advanced melanoma is considered the most aggressive and deadly form of skin cancer whose incidence has been rising over the past three decades. In the absence of treatment, the median overall survival for advanced-stage metastatic disease is less tha
Externí odkaz:
https://doaj.org/article/b4ac4159bea44b82a706e5f6f3c885c8
Autor:
Favour A. Akinjiyan, George Nassief, Jordan Phillipps, Tolulope Adeyelu, Andrew Elliott, Farah Abdulla, Alice Y. Zhou, George Souroullas, Kevin B. Kim, Ari Vanderwalde, Soo J. Park, George Ansstas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract ARID genes encode subunits of SWI/SNF chromatin remodeling complexes and are frequently mutated in human cancers. We investigated the correlation between ARID mutations, molecular features, and clinical outcomes in melanoma patients. Cutaneo
Externí odkaz:
https://doaj.org/article/12330a2b365b4ae9b93fc739ef7b1daa
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundImmunotherapy has revolutionized the treatment of patients with advanced melanoma as well as other cancers. Most studies, whether of interleukin-2 or checkpoint inhibitor therapies, have limited follow-up after 5 years, making the incidence
Externí odkaz:
https://doaj.org/article/2fd1c212131541e38968831fda7349d0
Autor:
Georgia Sofia Karachaliou, Rached Alkallas, Sarah B. Carroll, Chongshan Caressi, Danny Zakria, Nirali M. Patel, Dimitri G. Trembath, Jennifer A. Ezzell, Guillaume J. Pegna, Paul B. Googe, Jonathan P. Galeotti, Fatih Ayvali, Frances A. Collichio, Carrie B. Lee, David W. Ollila, Margaret L. Gulley, Douglas B. Johnson, Kevin B. Kim, Ian R. Watson, Stergios J. Moschos
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Melanoma-intrinsic activated β-catenin pathway, the product of the catenin beta 1 (CTNNB1) gene, has been associated with low/absent tumor-infiltrating lymphocytes, accelerated tumor growth, metastases development, and resistance
Externí odkaz:
https://doaj.org/article/e37d57623fe24adeb9a71ff470be1281
Autor:
Wei-Lien Wang, Bita Esmaeli, Patrick Hwu, Alexandre Reuben, Michael T Tetzlaff, Jason Roszik, Mariana Petaccia De Macedo, Yong Qin, Kathryn Bollin, Fernando Carapeto, Kevin B Kim, Khalida M Wani, Sujan T Reddy, Michelle D Williams, Dan S Gombos, Alexander J Lazar, Sapna P Patel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background To date, no systemic therapy, including immunotherapy, exists to improve clinical outcomes in metastatic uveal melanoma (UM) patients. To understand the role of immune infiltrates in the genesis, metastasis, and response to treatment for U
Externí odkaz:
https://doaj.org/article/3fed3b3cb79e42dfbf4d90c23d4d647c
Autor:
Elham Vosoughi, Jee Min Lee, James R. Miller, Mehdi Nosrati, David R. Minor, Roy Abendroth, John W. Lee, Brian T. Andrews, Lewis Z. Leng, Max Wu, Stanley P. Leong, Mohammed Kashani-Sabet, Kevin B. Kim
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background Melanoma brain metastasis is associated with an extremely poor prognosis, with a median overall survival of 4–5 months. Since 2011, the overall survival of patients with stage IV melanoma has been significantly improved with the
Externí odkaz:
https://doaj.org/article/486e831d368142f881409d2a8c76d6ac
Autor:
Baijia Jiang, MD, Maria M. Patino, MD, Andrew J. Gross, MD, Stanley P.L. Leong, MD, John C. Moretto, MD, Mohammed Kashani-Sabet, MD, Kevin B. Kim, MD
Publikováno v:
JAAD Case Reports, Vol 4, Iss 1, Pp 13-16 (2018)
Externí odkaz:
https://doaj.org/article/9f1e3fbc3860433da415a0169423ac61
Autor:
Kevin B. Kim, Patrick Hwu, Roland L. Bassett, John J. Wright, Janet E. Dancey, Wenbin Liu, Sanjay Gupta, Chaan S. Ng, Wanleng Deng, Sha Huang, Quanyun Xu, Timothy L. Madden, Kirk S. Culotta, Victor G. Prieto, Alexander J. Lazar, Wen-Jen Hwu, Agop Y. Bedikian, Nicholas E. Papadopoulos, Patricia S. Fox, Michael A. Davies
PDF file - 43K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6901326039a39074a1c67f22ef90dad
https://doi.org/10.1158/1078-0432.22444283.v1
https://doi.org/10.1158/1078-0432.22444283.v1
Autor:
Mohammed Kashani-Sabet, James E. Cleaver, Sancy A. Leachman, Dirk Schadendorf, Robert J. Debs, Sean McAllister, Liliana Soroceanu, Wilson Liao, Kevin B. Kim, Stanley P. Leong, James R. Miller, Altaf A. Dar, Mehdi Nosrati, Vladimir Bezrookove, David de Semir
Supplementary Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100bb3ac374086f7c7b4a561953df3f8
https://doi.org/10.1158/0008-5472.22429675
https://doi.org/10.1158/0008-5472.22429675
Autor:
Rodabe N. Amaria, Jordan D. Berlin, Allison S. Harney, Micaela B. Reddy, Carola Berking, Douglas B. Johnson, Matteo S. Carlino, Carla M.L. van Herpen, Filip Y.F.L. De Vos, Michael A. Postow, Paolo A. Ascierto, Jeffrey A. Sosman, Kevin B. Kim, Lisa Zimmer, Martin Schuler
Purpose:Enhanced MAPK pathway signaling and cell-cycle checkpoint dysregulation are frequent in NRAS-mutant melanoma and, as such, the regimen of the MEK inhibitor binimetinib and the selective CDK4/6 inhibitor ribociclib is a rational combination.Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa9203ee81d6cd6053b38bb1b9852e1
https://doi.org/10.1158/1078-0432.c.6532311.v1
https://doi.org/10.1158/1078-0432.c.6532311.v1