Evaluation of the Protective Efficacy of Different Doses of a Chlamydia abortus Subcellular Vaccine in a Pregnant Sheep Challenge Model for Ovine Enzootic Abortion

Autor: Morag Livingstone, Kevin Aitchison, Javier Palarea-Albaladejo, Francesca Chianini, Mara Silvia Rocchi, Sergio Gastón Caspe, Clare Underwood, Allen Flockhart, Nicholas Wheelhouse, Gary Entrican, Sean Ranjan Wattegedera, David Longbottom

Publikováno v: Animals, Vol 14, Iss 20, p 3004 (2024)

Chlamydia abortus causes the disease ovine enzootic abortion, which is one of the most infectious causes of foetal death in small ruminants worldwide. While the disease can be controlled using live and inactivated commercial vaccines, there is scope

Externí odkaz: https://doaj.org/article/07d8797f458c4142bdb22cae51c6e1bb

The 1B vaccine strain of Chlamydia abortus produces placental pathology indistinguishable from a wild type infection.

Autor: Sergio Gaston Caspe, Morag Livingstone, David Frew, Kevin Aitchison, Sean Ranjan Wattegedera, Gary Entrican, Javier Palarea-Albaladejo, Tom Nathan McNeilly, Elspeth Milne, Neil Donald Sargison, Francesca Chianini, David Longbottom

Publikováno v: PLoS ONE, Vol 15, Iss 11, p e0242526 (2020)

Chlamydia abortus is one of the most commonly diagnosed causes of infectious abortion in small ruminants worldwide. Control of the disease (Enzootic Abortion of Ewes or EAE) is achieved using the commercial live, attenuated C. abortus 1B vaccine stra

Externí odkaz: https://doaj.org/article/01afc79b89264a4b956c7935e5e3ef8b

Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS.

Autor: Morag Livingstone, Nicholas Wheelhouse, Hannah Ensor, Mara Rocchi, Stephen Maley, Kevin Aitchison, Sean Wattegedera, Kim Wilson, Michelle Sait, Victoria Siarkou, Evangelia Vretou, Gary Entrican, Mark Dagleish, David Longbottom

Publikováno v: PLoS ONE, Vol 12, Iss 5, p e0177653 (2017)

This study investigated the pathogenesis of two variant strains (LLG and POS) of Chlamydia abortus, in comparison to a typical wild-type strain (S26/3) which is known to be responsible for late term abortion in small ruminants. Challenge with the thr

Externí odkaz: https://doaj.org/article/c5a34f5e147440cc8929a4756a1b226c

Processing of Chlamydia abortus polymorphic membrane protein 18D during the chlamydial developmental cycle.

Autor: Nick M Wheelhouse, Michelle Sait, Kevin Aitchison, Morag Livingstone, Frank Wright, Kevin McLean, Neil F Inglis, David G E Smith, David Longbottom

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e49190 (2012)

Chlamydia possess a unique family of autotransporter proteins known as the Polymorphic membrane proteins (Pmps). While the total number of pmp genes varies between Chlamydia species, all encode a single pmpD gene. In both Chlamydia trachomatis (C. tr

Externí odkaz: https://doaj.org/article/e3e89932d7484df58f14fbd7d50cbdf3

Efficacy of Two Chlamydia abortus Subcellular Vaccines in a Pregnant Ewe Challenge Model for Ovine Enzootic Abortion

Autor: Cecilia Corbett, Kim Wilson, Morag Livingstone, Javier Palarea-Albaladejo, Mara Rocchi, Michelle Sait, Kevin Aitchison, Nick Wheelhouse, Sean Wattegedera, Gary Entrican, Francesca Chianini, David Longbottom

Publikováno v: Vaccines, Vol 9, Iss 898, p 898 (2021)
Vaccines, 2021, vol. 9, núm. 8, p. 898
Articles publicats (D-IMA)
DUGiDocs – Universitat de Girona
instname
Vaccines
Volume 9
Issue 8

Chlamydia abortus, the aetiological agent of enzootic abortion of ewes, is a major cause of reproductive loss in small ruminants worldwide, accounting for significant economic losses to the farming industry. Disease can be managed through the use of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2bd9b22b71f2ea7b6913c577ff4dfd
https://www.mdpi.com/2076-393X/9/8/898