Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Kevin A. Leslie"'
Autor:
Graeme F. Murray, Tia H. Turner, Daniel Guest, Kevin A. Leslie, Mohammad A. Alzubi, Senthil K. Radhakrishnan, J. Chuck Harrell, Jason Reed
Publikováno v:
Frontiers in Physics, Vol 7 (2019)
The development of resistance to initially successful cancer therapies is a major cause of the morbidity and mortality associated with cancer. Identifying evolving resistance at an early stage could inform clinical decision making to adapt therapies
Externí odkaz:
https://doaj.org/article/f4ce7a986b1045b697a7f7f2889700c6
Autor:
Melina Messing, Mypinder S. Sekhon, Michael R. Hughes, Sophie Stukas, Ryan L. Hoiland, Jennifer Cooper, Nyra Ahmed, Mark S. Hamer, Yicong Li, Samuel B. Shin, Lin Wei Tung, Cheryl L. Wellington, Don D. Sin, Kevin B. Leslie, Kelly M. McNagny
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The COVID-19 pandemic continues to challenge the capacities of hospital ICUs which currently lack the ability to identify prospectively those patients who may require extended management. In this study of 90 ICU COVID-19 patients, we evaluated serum
Externí odkaz:
https://doaj.org/article/e664c34af33143408e6843b6957ebf8c
Autor:
Anjali Saqi, MD, MBA, Kevin O. Leslie, MD, Andre L. Moreira, MD, PhD, Sylvie Lantuejoul, MD, PhD, Catherine Ann Shu, MD, Naiyer A. Rizvi, MD, Joshua R. Sonett, MD, Kosei Tajima, MS, Shawn W. Sun, PharmD, Barbara J. Gitlitz, MD, Thomas V. Colby, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 5, Pp 100310- (2022)
The efficacy of neoadjuvant treatment for NSCLC can be pathologically assessed in resected tissue. Major pathologic response (MPR) and pathologic complete response (pCR), defined as less than or equal to 10% and 0% viable tumor cells, respectively, a
Externí odkaz:
https://doaj.org/article/e87ed4b0d3b2461eb53709e10f63f4a4
Publikováno v:
Practical Pulmonary Pathology ISBN: 9780323795470
The airways are frequently involved in nonneoplastic lung diseases, and sometimes their involvement dominates the clinical picture. In these situations, the combination of clinical and radiologic findings is sometimes sufficient to reach a firm diagn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3a1284f93c13b28ac3ba50c8c617b5
https://doi.org/10.1016/b978-0-323-79547-0.00018-7
https://doi.org/10.1016/b978-0-323-79547-0.00018-7
Autor:
Maxwell L. Smith, Kevin O. Leslie
Publikováno v:
Practical Pulmonary Pathology ISBN: 9780323795470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f3295cf91620ad7134af5bdbc33dd31
https://doi.org/10.1016/b978-0-323-79547-0.00025-4
https://doi.org/10.1016/b978-0-323-79547-0.00025-4
Publikováno v:
Practical Pulmonary Pathology ISBN: 9780323795470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bd5825356aeae4f82d54bab06bc1049
https://doi.org/10.1016/b978-0-323-79547-0.00016-3
https://doi.org/10.1016/b978-0-323-79547-0.00016-3
Publikováno v:
Practical Pulmonary Pathology ISBN: 9780323795470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b008028a4bdd98b6dcf1efc8fd334d
https://doi.org/10.1016/b978-0-323-79547-0.00008-4
https://doi.org/10.1016/b978-0-323-79547-0.00008-4
Publikováno v:
Practical Pulmonary Pathology ISBN: 9780323795470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9538d06f23a5d8efbbbae4dd764ea68b
https://doi.org/10.1016/b978-0-323-79547-0.00006-0
https://doi.org/10.1016/b978-0-323-79547-0.00006-0
Autor:
Mattia Barbareschi, Staci Beamer, Mary Beth Beasley, Jennifer M. Boland, Alain C. Borczuk, Kelly J. Butnor, Yasmeen M. Butt, Alessandra Cancellieri, Alberto Cavazza, David B. Chapel, Oi-Yee Cheung, Andrew Churg, Giorgia Dalpiaz, Megan K. Dishop, Wafaa A. Elatre, Junya Fukuoka, Paolo Graziano, Dawn E. Jaroszewski, Andras Khoor, Brandon T. Larsen, Kevin O. Leslie, M. Cecilia Mengoli, Imre Noth, Mutsumi Ozasa, Stephen S. Raab, Anja C. Roden, Victor L. Roggli, Lynette M. Sholl, Maxwell L. Smith, William D. Travis, Robert W. Viggiano, Marina Vivero, W. Dean Wallace, Mark R. Wick, Joanne L. Wright, Stacey E. Mills
Publikováno v:
Practical Pulmonary Pathology ISBN: 9780323795470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69d28a9917e1fa95922dc1146531f34c
https://doi.org/10.1016/b978-0-323-79547-0.00004-7
https://doi.org/10.1016/b978-0-323-79547-0.00004-7
Autor:
James Morrison, Rachel H. Munday, Thomas O. Ronson, Matthew R. Tatton, Hucheng Zhao, Calum Cook, Daniël de Bruin, Kevin William Leslie, Kuangchu Dai, David Buttar, Catalina Ferrer, James Douglas
Publikováno v:
The Journal of Organic Chemistry. 87:2075-2086
Route design and proof of concept synthesis was conducted on a synthetically challenging atropisomeric KRASG12C inhibitor to support clinical API manufacture. Improvements to the synthesis of a chiral piperazine fragment gave reduced step count and s