Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kevin A. Camphausen"'
Publikováno v:
Biomedical Research Journal, Vol 2, Iss 1, Pp 105-119 (2015)
Radiotherapy remains the standard treatment for glioblastoma multiforme (GBM) following surgical resection. Given the aberrant expression of human epidermal growth factor receptor 2 (HER2) and epidermal growth factor receptor (EGFR) which may play a
Externí odkaz:
https://doaj.org/article/35d769a315ff40a088697d1cbc14beec
Autor:
Jenna E, AbuSalim, Kazutoshi, Yamamoto, Natsuko, Miura, Burchelle, Blackman, Jeffrey R, Brender, Chandrasekhar, Mushti, Tomohiro, Seki, Kevin A, Camphausen, Rolf E, Swenson, Murali C, Krishna, Aparna H, Kesarwala
Publikováno v:
ACS Chem Biol
Alpha-ketoglutarate (α-KG) is a key metabolite and signaling molecule in cancer cells, but the low permeability of α-KG limits the study of α-KG mediated effects in vivo. Recently, cell-permeable monoester and diester α-KG derivatives have been s
Autor:
Tatsuya Kawai, Jeffrey R. Brender, Jennifer A. Lee, Tamalee Kramp, Shun Kishimoto, Murali C. Krishna, Philip Tofilon, Kevin A. Camphausen
Publikováno v:
NMR in Biomedicine. 34
Autor:
Charlotte M. Degorre, Ian C. Sutton, Stacey L. Lehman, Uma T. Shankavaram, Kevin A. Camphausen, Philip J. Tofilon
Publikováno v:
Cancer Research. 82:6057-6057
We have previously reported (Int J Radiat Oncol Biol Phys. 107(1):194-201, 2020) that human GBM-stem like cells (GSCs) implanted into the right striatum of nude mice migrate/invade throughout the right hemisphere (RH) as well as into the olfactory bu
Autor:
Dove-Anna Johnson, Michelle Pleet, Joshua Aden Welsh, Sean Cook, Jason Savage, Nooshin Mirza Nasiri, Kevin A. Camphausen, Kenneth D. Aldape, James L. Gulley, Beverly A Mock, Jay A. Berzofsky, Steve Jacobson, Jennifer C Jones
Publikováno v:
Journal of Clinical Oncology. 40:3046-3046
3046 Background: Extracellular Vesicles (EV) are of broad interest as carriers of molecular signatures of tumor progression and cancer treatment response. EVs, which contain nucleic acids, lipids, and proteins, are released from cells for waste excre
Autor:
Tatsuya, Kawai, Jeffrey R, Brender, Jennifer A, Lee, Tamalee, Kramp, Shun, Kishimoto, Murali C, Krishna, Philip, Tofilon, Kevin A, Camphausen
Publikováno v:
Nmr in Biomedicine
Dynamic nuclear polarization (DNP) of 13C‐labeled substrates enables the use of magnetic resonance imaging (MRI) to monitor specific enzymatic reactions in tumors and offers an opportunity to investigate these differences. In this study, DNP‐MRI
Publikováno v:
Oncology (Williston Park, N.Y.). 31(3)
Radiation therapy continues to be a key component in the management of pediatric malignancies. Increasing the likelihood of cure while minimizing late treatment toxicity in these young patients remains the primary goal. Within the realm of central ne
Publikováno v:
Oncology (Williston Park, N.Y.). 31(3)
Newer approaches in the field of radiation therapy have raised the bar in the treatment of central nervous system (CNS) malignancies, with recognized advances that have aimed to increase the therapeutic index by improving conformality of the radiatio
Publikováno v:
Cancer Research. 79:LB-134
Brain tumor xenografts initiated from human GBM stem-like cells (GSCs) mimic many of the characteristics of GBM in situ including extensive invasiveness and migration. Using a GSC orthotopic brain tumor model, we show that the CD133+ NSC11 cells, a w
Autor:
Tatsuya Kawai, Murali C. Krishna, Tamalee Kramp, Jeffery R. Brender, Philip Tofilon, Kevin A. Camphausen
Publikováno v:
Cancer Research. 79:1944-1944
OBJECTIVES: Since the cancer stem-like cells (CSCs) play an important role in the resistance against radiation therapy due to its different metabolic profile, investigation of the specific metabolic characteristics of CSCs is valuable. Dynamic nuclea