Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kevin A Rea"'
Autor:
Jerry Vockley, Kristin J Hope, Kevin A Rea, Tariq A. Akhtar, Aaron D. Schimmer, Al-Walid Mohsen, Nawaz Ahmed, Paul A. Spagnuolo, Angelo D'Alessandro, Richard W. Smith, Matthew Tcheng, David A. Hess, Eric Bohrnsen, Mark D. Minden, Preethi Jayanth, Alessia Roma
Publikováno v:
Blood
Paediatrics Publications
Paediatrics Publications
Acute myeloid leukemia (AML) cells have an atypical metabolic phenotype characterized by increased mitochondrial mass, as well as a greater reliance on oxidative phosphorylation and fatty acid oxidation (FAO) for survival. To exploit this altered met
Autor:
Tariq A Akhtar, Kevin A Rea, George A. O'Doherty, Richard W. Smith, Vitor L S Cunha, Xiaofan Liu, Angelo D'Alessandro, Paul A. Spagnuolo, Nawaz Ahmed, Todd L. Lowary, Mark D. Minden, Jerry Vockley, Matthew Tcheng
Publikováno v:
Food Funct
Avocado consumption is associated with numerous health benefits. Avocadyne is a terminally unsaturated, 17-carbon long acetogenin found almost exclusively within avocados with noted anti-leukemia and anti-viral properties. In this study, specific str
Autor:
José A. Casaretto, Kevin A Rea, Jennifer Geddes-McAlister, Arjun Sukumaran, Tariq A. Akhtar, M. Sameer Al-Abdul-Wahid, Steven J. Rothstein
Publikováno v:
Phytochemistry. 164:162-171
In addition to the psychoactive constituents that are typically associated with Cannabis sativa L., there exist numerous other specialized metabolites in this plant that are believed to contribute to its medicinal versatility. This study focused on t
Autor:
Katarzyna Gawarecka, Kevin A Rea, Witold Danikiewicz, Hanna Siekierska, Lilia K.A. Virta, Liliana Surmacz, Maritza Vatta, Daniel Buszewicz, Ewa Swiezewska, Kristen Van Gelder, Magdalena Kania, Tariq A. Akhtar, Przemyslaw Surowiecki, Jacek Wójcik
Publikováno v:
The Plant Cell. 29:1709-1725
Plants accumulate a family of hydrophobic polymers known as polyprenols, yet how they are synthesized, where they reside in the cell, and what role they serve is largely unknown. Using Arabidopsis thaliana as a model, we present evidence for the invo
Autor:
Al-Walid Mohsen, Richard W. Smith, Kevin A Rea, Jerry Vockley, Matthew Tcheng, David A. Hess, Kristin J Hope, Rose Hurren, Gale G. Bozzo, Nawaz Ahmed, Preethi Jayanth, Mark D. Minden, Tariq A. Akhtar, Paul A. Spagnuolo, Alessia Roma, Aaron D. Schimmer
Publikováno v:
Blood. 134:3922-3922
Targeting cell metabolism has emerged as a viable treatment strategy in acute myeloid leukemia (AML), a malignant hematological disease characterized by poor patient outcomes and limited chemotherapeutic options. Compared to the normal hematopoietic
Autor:
Paul A. Spagnuolo, Tariq A. Akhtar, Alessia Roma, Michael Buraczynski, Nawaz Ahmed, Preethi Jayanth, Kevin A Rea, Matthew Tcheng
Publikováno v:
Molecular Nutrition & Food Research. 63:1900688
Scope The effects of an avocado-derived fatty acid oxidation (FAO) inhibitor, avocatin B (AvoB), on glucose and lipid metabolism in models of diet-induced obesity (DIO) and in vitro models of lipotoxicity are evaluated. The safety of its oral consump
Autor:
Tariq A, Akhtar, Przemysław, Surowiecki, Hanna, Siekierska, Magdalena, Kania, Kristen, Van Gelder, Kevin A, Rea, Lilia K A, Virta, Maritza, Vatta, Katarzyna, Gawarecka, Jacek, Wojcik, Witold, Danikiewicz, Daniel, Buszewicz, Ewa, Swiezewska, Liliana, Surmacz
Publikováno v:
The Plant cell. 29(7)
Plants accumulate a family of hydrophobic polymers known as polyprenols, yet how they are synthesized, where they reside in the cell, and what role they serve is largely unknown. Using