Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Kevin A Janes"'
Autor:
Kevin A Janes
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009379 (2021)
Externí odkaz:
https://doaj.org/article/8120cff9efdc4a6a87ab5f0a7a808485
Autor:
Derek M R Nye, Richard M Albertson, Alexis T Weiner, J Ian Hertzler, Matthew Shorey, Deborah C I Goberdhan, Clive Wilson, Kevin A Janes, Melissa M Rolls
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000657 (2020)
While many regulators of axon regeneration have been identified, very little is known about mechanisms that allow dendrites to regenerate after injury. Using a Drosophila model of dendrite regeneration, we performed a candidate screen of receptor tyr
Externí odkaz:
https://doaj.org/article/f335bd2fb73341978ccd9bb1deec833d
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103190- (2024)
Summary: We present a protocol to generate highly multiplexed spatial data at cellular and subcellular resolutions using iterative indirect immunofluorescence imaging (4i). We describe streamlined steps for using 4i across fixed cultured cells, forma
Externí odkaz:
https://doaj.org/article/67203e541dcb49dd957caa3f3b8becb6
Autor:
Jianhao Zeng, Shambhavi Singh, Xian Zhou, Ying Jiang, Eli Casarez, Kristen A. Atkins, Kevin A. Janes, Hui Zong
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/d7589bf49a1a4ceea9408d8534e9b168
Autor:
Anna Kuchina, Jason Yang, Bree Aldridge, Kevin A. Janes, Naeha Subramanian, Nevan J. Krogan, Mehdi Bouhaddou, Shirit Einav, Jason Papin, Ronald N. Germain
Publikováno v:
Cell Systems. 13:945-949
Leading researchers at the intersection of infectious disease and systems biology speak about how systems approaches have influenced modern infectious disease research and what these tools can offer for the future of the field.
Autor:
B. Bishal Paudel, Su-Fern Tan, Todd E. Fox, Johnson Ung, Jeremy Shaw, Wendy Dunton, Irene Lee, Arati Sharma, Aaron D. Viny, Brian M. Barth, Martin S. Tallman, Myles Cabot, Francine E. Garrett-Bakelman, Ross L. Levine, Mark Kester, David Claxton, David J. Feith, Kevin A. Janes, Thomas P. Loughran
Publikováno v:
bioRxiv
Acute myeloid leukemia (AML) is an aggressive disease with complex and heterogeneous biology. Although several genomic classifications have been proposed, there is a growing interest in going beyond genomics to stratify AML. In this study, we profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d818fb462fe8955009591cb49d720dd6
https://europepmc.org/articles/PMC10153188/
https://europepmc.org/articles/PMC10153188/
Publikováno v:
Nature Communications. 14
Activation of HER2/ErbB2 coincides with escape from ductal carcinoma in situ (DCIS) premalignancy and disrupts 3D organization of cultured breast-epithelial spheroids. The 3D phenotype is infrequent, however, and mechanisms for its incomplete penetra
Autor:
Kevin A. Janes, Hui Zong, Shambhavi Singh, Lauren K. Rosenfeld, Jungeun Kim, Lixin Wang, Rui P. Galvao, Matthew D. Sutcliffe
Cancer evolves from premalignant clones that adopt unusual cell states to achieve transformation. We previously pinpointed the oligodendrocyte precursor cell (OPC) as a cell of origin for glioma, but the early changes of mutant OPCs during premaligna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1068a33aaacd805715bca581c0edaac
https://doi.org/10.1158/0008-5472.c.6513202.v1
https://doi.org/10.1158/0008-5472.c.6513202.v1
Autor:
Kevin A. Janes, Hui Zong, Shambhavi Singh, Lauren K. Rosenfeld, Jungeun Kim, Lixin Wang, Rui P. Galvao, Matthew D. Sutcliffe
Candidate male- and female-specific regulatory heterogeneities in mutant cells at 12 dpi (Sheet 1) and 90 dpi (Sheet 2). Shared candidates are shown as RHEGs for each day.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d15e29932b7d6f364a83d1ba9a58c2
https://doi.org/10.1158/0008-5472.22428976.v1
https://doi.org/10.1158/0008-5472.22428976.v1
Autor:
Kevin A. Janes, Jennifer A. Harvey, Kristen A. Atkins, Kathy Repich, Matthew D. Sutcliffe, Shambhavi Singh
Full METASCAPE analysis of RHEGs organized by gene annotation (Sheet 1), categorical enrichments (Sheet 2), TRRUST candidate regulators (Sheet 3), and predicted enrichments for transcription factor (TF) targets (Sheet 4).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7661ae0a01fee5d906095ea9d500976
https://doi.org/10.1158/0008-5472.22429299
https://doi.org/10.1158/0008-5472.22429299