Zobrazeno 1 - 10
of 474
pro vyhledávání: '"Kevin W. Plaxco"'
Autor:
Alex M. Downs, Julian Gerson, Kaylyn K. Leung, Kevin M. Honeywell, Tod Kippin, Kevin W. Plaxco
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Electrochemical aptamer-based (EAB) sensors support the real-time, high frequency measurement of pharmaceuticals and metabolites in-situ in the living body, rendering them a potentially powerful technology for both research and clinical appl
Externí odkaz:
https://doaj.org/article/1f5dd011f9334c69a5b0be1adec67bf7
Publikováno v:
Annual Review of Biophysics. 52:319-337
Cooperativity (homotropic allostery) is the primary mechanism by which evolution steepens the binding curves of biomolecular receptors to produce more responsive input–output behavior in biomolecular systems. Motivated by the ubiquity with which na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b3932e2089fa0f5c358a349b324661
https://doi.org/10.1146/annurev-biophys-091222-082247
https://doi.org/10.1146/annurev-biophys-091222-082247
Autor:
Kaylyn K. Leung, Julian Gerson, Nicole Emmons, Brian Roehrich, Elsi Verrinder, Lisa C. Fetter, Tod E. Kippin, Kevin W. Plaxco
Publikováno v:
The Analyst. 148:1562-1569
Electrochemical aptamer-based sensors are the first molecular monitoring technology that support real-time measurements in the living body. Electrode placement plays a key role in the performance of these sensors when they are deployed for intravenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b8db1d2720d322373739a709bd6b1dd
https://doi.org/10.1039/d2an02096c
https://doi.org/10.1039/d2an02096c
Publikováno v:
Lab on a Chip. 23:1339-1348
We argue that the introduction of high-frequency, real-time biosensors into LoCs could be used to establish high-value feed-back control functionalities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d85a98c3d3dc81ff3a2d15ce06c0de
https://doi.org/10.1039/d2lc00716a
https://doi.org/10.1039/d2lc00716a
Publikováno v:
Biochemical and Biophysical Research Communications. 668:1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277eed0b963cb805f153b8c54e6a2836
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100894271
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100894271
Autor:
Alex M. Downs, Kevin W. Plaxco
Publikováno v:
ACS sensors, vol 7, iss 10
ACS Sens
ACS Sens
The continuous, real-time measurement of specific molecules in situ in the body would greatly improve our ability to understand, diagnose, and treat disease. The vast majority of continuous molecular sensing technologies, however, either (1) rely on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f6bcb48ebe9ecc8be1abd2f581746d
https://doi.org/10.1021/acssensors.2c01428
https://doi.org/10.1021/acssensors.2c01428
Autor:
Philip A. Vieira, Christina B. Shin, Netzahualcóyotl Arroyo-Currás, Gabriel Ortega, Weiwei Li, Arturo A. Keller, Kevin W. Plaxco, Tod E. Kippin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Clinical drug dosing would, ideally, be informed by high-precision, patient-specific data on drug metabolism. The direct determination of patient-specific drug pharmacokinetics (“peaks and troughs”), however, currently relies on cumbersome, labor
Externí odkaz:
https://doaj.org/article/cb05d35fd4ed4cbaaf276ac84facb255
Publikováno v:
British Journal of Clinical Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29f7a7d5f96cb46fcfde12ea36dac291
https://doi.org/10.1111/bcp.15756
https://doi.org/10.1111/bcp.15756
Autor:
Julian Gerson, Murat Kaan Erdal, Matthew H. McDonough, Kyle L. Ploense, Philippe Dauphin-Ducharme, Kevin M. Honeywell, Kaylyn K. Leung, Netzahualcoyotl Arroyo-Curras, Jenny M. Gibson, Nicole A. Emmons, Wendy Meiring, Joao P. Hespanha, Kevin W. Plaxco, Tod E. Kippin
Publikováno v:
Science Advances. 9
Knowledge of drug concentrations in the brains of behaving subjects remains constrained on a number of dimensions, including poor temporal resolution and lack of real-time data. Here, however, we demonstrate the ability of electrochemical aptamer-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cdba0334e8e21a5a083277e181f40ba
https://doi.org/10.1126/sciadv.adg3254
https://doi.org/10.1126/sciadv.adg3254
Autor:
Charlotte Flatebo, William R. Conkright, Meaghan E. Beckner, Robert H. Batchelor, Tod E. Kippin, Jason Heikenfeld, Kevin W. Plaxco
Publikováno v:
Journal of Science and Medicine in Sport.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcff58109e267103650070daa3fac41d
https://doi.org/10.1016/j.jsams.2023.01.010
https://doi.org/10.1016/j.jsams.2023.01.010