Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Kevin, Vanvarenberg"'
Autor:
Teenesha Chellen, Mathilde Bausart, Pierre Maus, Kevin Vanvarenberg, Nisha Limaye, Véronique Préat, Alessio Malfanti
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101057- (2024)
Glioblastoma (GBM) is an aggressive brain tumor, with a highly immunosuppressive tumor immune microenvironment (TIME). In this work, we investigated the use of the STimulator of INterferon Genes (STING) pathway as an effective means to remodel the GB
Externí odkaz:
https://doaj.org/article/8706bd35314b47c0ba41325e3a3ecd79
Autor:
Jérôme Conq, Nicolas Joudiou, Bernard Ucakar, Kevin Vanvarenberg, Véronique Préat, Bernard Gallez
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1957 (2023)
Background: While the blood–brain barrier (BBB) is often compromised in glioblastoma (GB), the perfusion and consequent delivery of drugs are highly heterogeneous. Moreover, the accessibility of drugs is largely impaired in the margins of the tumor
Externí odkaz:
https://doaj.org/article/366020fb853f4fc9a179cc6125b7309b
Autor:
Alessandra Lopes, Sophie Ligot, Gaëlle Vandermeulen, Chiara Bastiancich, Mathilde Bausart, Laure Lambricht, Kevin Vanvarenberg, Bernard Ucakar, Bernard Gallez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background Strategies to increase nucleic acid vaccine immunogenicity are needed to move towards clinical applications in oncology. In this study, we designed a new generation of DNA vaccines, encoding an engineered vesicular stomatitis virus glycopr
Externí odkaz:
https://doaj.org/article/4f8d4102ed44483b8eab7aa575b3f576
Autor:
Mathilde Bausart, Kevin Vanvarenberg, Bernard Ucakar, Alessandra Lopes, Gaëlle Vandermeulen, Alessio Malfanti, Véronique Préat
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1025 (2022)
Combination immunotherapy has emerged as a promising strategy to increase the immune response in glioblastoma (GBM) and overcome the complex immunosuppression occurring in its microenvironment. In this study, we hypothesized that combining DNA vaccin
Externí odkaz:
https://doaj.org/article/b87c99c6baf34adbbc9ce6efd10ce803
Autor:
Alessandra Lopes, Kevin Vanvarenberg, Špela Kos, Sophie Lucas, Didier Colau, Benoît Van den Eynde, Véronique Préat, Gaëlle Vandermeulen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract DNA vaccination against cancer has become a promising strategy for inducing a specific and long-lasting antitumor immunity. However, DNA vaccines fail to generate potent immune responses when used as a single therapy. To enhance their activi
Externí odkaz:
https://doaj.org/article/8a185f7e782e4e90bd9cd7722f8cbb6c
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 404-415 (2017)
DNA vaccine can be modified to increase protein production and modulate immune response. To enhance the efficiency of a P815 mastocytoma DNA vaccine, the P1A gene sequence was optimized by substituting specific codons with synonymous ones while modul
Externí odkaz:
https://doaj.org/article/bf00835b486b4d029ecd397753fffdb2
Autor:
Spela Kos, Alessandra Lopes, Veronique Preat, Maja Cemazar, Ursa Lampreht Tratar, Bernard Ucakar, Kevin Vanvarenberg, Gregor Sersa, Gaelle Vandermeulen
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217762 (2019)
We aimed to explore whether the combination of intradermal DNA vaccination, to boost immune response against melanoma antigens, and immune checkpoint blockade, to alleviate immunosuppression, improves antitumor effectiveness in a murine B16F10 melano
Externí odkaz:
https://doaj.org/article/a51058ce69a64fbf8f44ce52ef40d79c
Publikováno v:
Drug Delivery and Translational Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d06659565780543693eb54c5017263
https://doi.org/10.1007/s13346-023-01337-4
https://doi.org/10.1007/s13346-023-01337-4
Autor:
Mathilde Bausart, Giulia Rodella, Mathilde Dumont, Bernard Ucakar, Kevin Vanvarenberg, Alessio Malfanti, Véronique Préat
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 50:102681
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b1ed95e3746a48e83349460d6380fb
https://doi.org/10.1016/j.nano.2023.102681
https://doi.org/10.1016/j.nano.2023.102681
Autor:
Véronique Préat, Konstantin Moshkunov, Benjamin Tomasetti, Matthias Lorenz, Thomas Daphnis, Filip Lemière, Kevin Vanvarenberg, Christine Dupont, Jusal Quanico, Arnaud Delcorte, Geert Baggerman, Vincent Delmez
Publikováno v:
The analyst
The Analyst
The Analyst, Vol. 146, no.21, p. 6506-6519 (2021)
The Analyst
The Analyst, Vol. 146, no.21, p. 6506-6519 (2021)
Sensitivity to molecular ions remains a limiting factor for high resolution imaging mass spectrometry of organic and biological materials. Here, we investigate a variant of matrix-enhanced secondary ion mass spectrometry in which the transfer of matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5145cade5522dfc230633e1cc842cffe
https://doi.org/10.1039/d1an00727k
https://doi.org/10.1039/d1an00727k