Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kevin, Reverse"'
Autor:
Jean‐Guy Boiteau, Gregoire Mouis, Kevin Reverse, Estelle Surget, Gaetan Boccadifuoco, Sophie Dufaÿ
Publikováno v:
Magnetic Resonance in Chemistry. 60:1185-1188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2ce6985edfb530955cb2094ce5cd952
https://doi.org/10.1002/mrc.5302
https://doi.org/10.1002/mrc.5302
Author response for 'Complete 1 H, 13 C and 15 N assignments of the minor isomer of codeine N‐oxide'
Autor:
null Jean‐Guy Boiteau, null Gregoire Mouis, null Kevin Reverse, null Estelle Surget, null Gaetan Boccadifuoco, null Sophie Dufaÿ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cccdeb60d0343b71c9b9e8da00b6f1e
https://doi.org/10.1002/mrc.5302/v2/response1
https://doi.org/10.1002/mrc.5302/v2/response1
Autor:
Jean-Guy, Boiteau, Gregoire, Mouis, Kevin, Reverse, Estelle, Surget, Gaetan, Boccadifuoco, Sophie, Dufaÿ
Publikováno v:
Magnetic resonance in chemistry : MRCREFERENCES. 60(12)
Codeine N-oxide 2 is an active metabolite of codeine obtained by oxidation and observed as a degradant in codeine drug products such as syrups. Oxidation of codeine's N-methyl function can deliver two regio-isomers due to chirality of the tetra-subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0f7cc8dce7ddd41bcd72473dffdfaeb
https://pubmed.ncbi.nlm.nih.gov/35919948
https://pubmed.ncbi.nlm.nih.gov/35919948
Autor:
Corinne Millois, Loïc Tomas, Catherine Comino, Laurence Dumais, Sandrine Talano, Kevin Reverse, Céline Mathieu, Craig S. Harris, Nicolas Vanthuyne, Grégoire Mouis, Anne-Laurence Ghilini, Laurent F. Hennequin, Claire Bouix-Peter, Vincent Rodeschini, Ghizlane El-Bazbouz, Laurence Clary, Sandrine Chambon, Romain Pierre, Jean-François Fournier, Anne Brethon
Publikováno v:
Tetrahedron
Tetrahedron, Elsevier, 2018, 74 (37), pp.4805-4822. ⟨10.1016/j.tet.2018.07.029⟩
Tetrahedron, 2018, 74 (37), pp.4805-4822. ⟨10.1016/j.tet.2018.07.029⟩
Tetrahedron, Elsevier, 2018, 74 (37), pp.4805-4822. ⟨10.1016/j.tet.2018.07.029⟩
Tetrahedron, 2018, 74 (37), pp.4805-4822. ⟨10.1016/j.tet.2018.07.029⟩
International audience; During our search for topically-active Caspase-1 inhibitors, we identified a novel class of potent in-hibitors based on a 1,3,5-trisubstituted uracil motif equipped with an L-aspartate semi-aldehyde derived warhead. In the lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fec40dca9ff1ebf6ef20f7e1e77cb56
https://doi.org/10.1016/j.tet.2018.07.029
https://doi.org/10.1016/j.tet.2018.07.029
Autor:
Didier M. Roche, Danielle Orfila, Ghizlane El-Bazbouz, Laurence Dumais, Laurent F. Hennequin, Céline Mathieu, Michèle Aurelly, Jerome Aubert, Claude Lardy, Etienne Thoreau, Anne-Pascale Luzy, Claire Bouix-Peter, Kenny Mebrouk, T. Isabet, Jean-François Fournier, Kevin Reverse, Catherine Comino, Corinne Millois, Anne-Laurence Ghilini, Jonathan Pascau, Sandrine Talano, Anne Brethon, Craig S. Harris, Romain Pierre, Sandrine Chambon, Laurence Clary, Olivier Christin, Laurent Chantalat, Vincent Rodeschini
Publikováno v:
Journal of Medicinal Chemistry. 61:4030-4051
The use of an interleukin β antibody is currently being investigated in the clinic for the treatment of acne, a dermatological disorder affecting 650M persons globally. Inhibiting the protease responsible for the cleavage of inactive pro-IL1β into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec019288b4b7ac46663d3c2d49c71c93
https://doi.org/10.1021/acs.jmedchem.8b00067
https://doi.org/10.1021/acs.jmedchem.8b00067
Autor:
Craig S. Harris, Isabelle Cardinaud, Feriel Hacini-Rachinel, Nicolas Rodeville, Audrey Beillard, Arnaud Reitz, Marilyne Bourotte, Benoit Deprez, Laetitia Bonnary, Catherine Comino, Corinne Millois, Delphine Spiesse, Claire Bouix-Peter, Denis Duvert, Jean-Guy Boiteau, Jean-Marie Arlabosse, Yushma Bhurruth-Alcor, Anne-Pascale Luzy, Laurent F. Hennequin, Gaëlle Polge, Emmanuel Vial, Loïc Tomas, Samuel Tabet, Kevin Reverse, Arnaud Mathieu, Artur Pinto, Angélique Feret, Karine Bouquet, Gilles Ouvry, Stéphanie Astri, Nicolas Orsini, Jonathan Pascau, Nathalie Taquet, David Piwnica, Patricia Rossio
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:945-956
Targeting the TNFα pathway is a validated approach to the treatment of psoriasis. In this pathway, TACE stands out as a druggable target and has been the focus of in-house research programs. In this article, we present the discovery of clinical cand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4758b7574647be3dbf23c8335599b665
https://doi.org/10.1016/j.bmc.2017.07.054
https://doi.org/10.1016/j.bmc.2017.07.054
Autor:
Arnaud Reitz, Corinne Millois, Marilyne Bourotte, Feriel Hacini-Rachinel, Carine Rosignoli, Arnaud Mathieu, Sandrine Chambon, Denis Duvert, Anne-Pascale Luzy, Laetitia Bonnary, Gwenaëlle Duvert, Gilles Ouvry, Jonathan Pascau, Craig S. Harris, Benoit Deprez, Laurent F. Hennequin, Catherine Comino, Yushma Bhurruth-Alcor, Yaël Berton, Nathalie Taquet, Claire Bouix-Peter, Gaëlle Polge, Kevin Reverse, Artur Pinto, Karine Bouquet
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:1848-1853
Targeting the Tumor Necrosis Factor α signalling with antibodies has led to a revolution in the treatment of psoriasis. Locally inhibiting Tumor Necrosis Factor α Converting Enzyme (TACE or ADAM17) could potentially mimic those effects and help tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6d576b781466f2d73bb18129c36d97
https://doi.org/10.1016/j.bmcl.2017.02.035
https://doi.org/10.1016/j.bmcl.2017.02.035