Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Kevin, Petrie"'
Autor:
Yordan Sbirkov, Tsvetomira Ivanova, Hasan Burnusuzov, Kalina Gercheva, Kevin Petrie, Tino Schenk, Victoria Sarafian
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Childhood acute lymphoblastic leukaemia (cALL) accounts for about one third of all paediatric malignancies making it the most common cancer in children. Alterations in tumour cell metabolism were first described nearly a century ago and have been ack
Externí odkaz:
https://doaj.org/article/85e33fa6f63e47e7ba5a4076446c5f00
Autor:
Samuel Waxman, Ming-Ming Zhou, Eduardo Farias, Arthur Zelent, Christopher J. Lord, Alan Ashworth, Yordan Sbirkov, Rachel Brough, Jessica Frankum, Edgardo V. Ariztia, Rajal Sharma, Shuai Yang, Nidhi Bansal, Rossitza Christova, Veronica Gil, Louise Howell, Mihaly Mezei, Lei Zeng, Boris A. Leibovitch, Kevin Petrie, Yeon-Jin Kwon
Supplementary Table S1 and Fig S1 and S2. Supplementary Table 1: qPCR primers used in this study; Supplementary Figure S1: Structures of compounds screened in Figure 1A and 1B; Supplementary Figure S2: Proximity ligation assay (PLA) analyzing SIN3A-M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2661226bcf1adfebdb4ad0b4e75309
https://doi.org/10.1158/1535-7163.22501737.v1
https://doi.org/10.1158/1535-7163.22501737.v1
Autor:
Samuel Waxman, Ming-Ming Zhou, Eduardo Farias, Arthur Zelent, Christopher J. Lord, Alan Ashworth, Yordan Sbirkov, Rachel Brough, Jessica Frankum, Edgardo V. Ariztia, Rajal Sharma, Shuai Yang, Nidhi Bansal, Rossitza Christova, Veronica Gil, Louise Howell, Mihaly Mezei, Lei Zeng, Boris A. Leibovitch, Kevin Petrie, Yeon-Jin Kwon
Supplementary Table S2. List of genes with expression regulated by selamectin treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359c53a496fbbd8957c2887bf8f293a8
https://doi.org/10.1158/1535-7163.22501731.v1
https://doi.org/10.1158/1535-7163.22501731.v1
Autor:
Samuel Waxman, Ming-Ming Zhou, Eduardo Farias, Arthur Zelent, Christopher J. Lord, Alan Ashworth, Yordan Sbirkov, Rachel Brough, Jessica Frankum, Edgardo V. Ariztia, Rajal Sharma, Shuai Yang, Nidhi Bansal, Rossitza Christova, Veronica Gil, Louise Howell, Mihaly Mezei, Lei Zeng, Boris A. Leibovitch, Kevin Petrie, Yeon-Jin Kwon
Triple-negative breast cancers (TNBC) lacking estrogen, progesterone, and HER2 receptors account for 10% to 20% of breast cancer and are indicative of poor prognosis. The development of effective treatment strategies therefore represents a pressing u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56370da14bb776869d71153456a22616
https://doi.org/10.1158/1535-7163.c.6536886.v1
https://doi.org/10.1158/1535-7163.c.6536886.v1
Autor:
Veronica S. Gil, Govind Bhagat, Louise Howell, Jiyuan Zhang, Chae H. Kim, Sven Stengel, Francisco Vega, Arthur Zelent, Kevin Petrie
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 12, Pp 1483-1495 (2016)
Histone deacetylase 9 (HDAC9) is expressed in B cells, and its overexpression has been observed in B-lymphoproliferative disorders, including B-cell non-Hodgkin lymphoma (B-NHL). We examined HDAC9 protein expression and copy number alterations in pri
Externí odkaz:
https://doaj.org/article/a02931d6d6d448e393a7ca0d30cc23bb
Autor:
Jan J. Molenaar, Louis Chesler, Huib N. Caron, Rogier Versteeg, Robbert J. Kok, Rolf W. Sparidans, Kevin Petrie, Simon P. Robinson, Albert Hallsworth, Yann Jamin, Carel J.M. van Noesel, Ilona J.M. den Hartog, Marli E. Ebus, Evon Poon, M. Emmy M. Dolman
Supplementary Tables S1-3. Table S1. IC25/50/75 and LC50 values of AT7519 for MYCN-amplified and non-MYCN-amplified neuroblastoma cell lines and cell seeding densities used to perform MTT cell proliferation assays (96-well plates). IC25/50/75 and LC5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ebcc78bfc11a54290daef6f42738a0
https://doi.org/10.1158/1078-0432.22454805
https://doi.org/10.1158/1078-0432.22454805
Autor:
Jan J. Molenaar, Louis Chesler, Huib N. Caron, Rogier Versteeg, Robbert J. Kok, Rolf W. Sparidans, Kevin Petrie, Simon P. Robinson, Albert Hallsworth, Yann Jamin, Carel J.M. van Noesel, Ilona J.M. den Hartog, Marli E. Ebus, Evon Poon, M. Emmy M. Dolman
Purpose: MYCN-dependent neuroblastomas have low cure rates with current multimodal treatment regimens and novel therapeutic drugs are therefore urgently needed. In previous preclinical studies, we have shown that targeted inhibition of cyclin-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3cc7892d78b44f7f43dd133ff375f8
https://doi.org/10.1158/1078-0432.c.6522837.v1
https://doi.org/10.1158/1078-0432.c.6522837.v1
Autor:
Jan J. Molenaar, Louis Chesler, Huib N. Caron, Rogier Versteeg, Robbert J. Kok, Rolf W. Sparidans, Kevin Petrie, Simon P. Robinson, Albert Hallsworth, Yann Jamin, Carel J.M. van Noesel, Ilona J.M. den Hartog, Marli E. Ebus, Evon Poon, M. Emmy M. Dolman
Supplementary Materials and Methods. Detailed protocol for cell culturing, in vitro and in vivo Western Blotting, in vitro FACS analysis, in vitro synergy studies and in vivo immunohistochemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd734fbdfced6b5caa6131627babed4
https://doi.org/10.1158/1078-0432.22454808
https://doi.org/10.1158/1078-0432.22454808
Autor:
Jan J. Molenaar, Louis Chesler, Huib N. Caron, Rogier Versteeg, Robbert J. Kok, Rolf W. Sparidans, Kevin Petrie, Simon P. Robinson, Albert Hallsworth, Yann Jamin, Carel J.M. van Noesel, Ilona J.M. den Hartog, Marli E. Ebus, Evon Poon, M. Emmy M. Dolman
Supplementary figures S1-8. Fig. S1. Sensitivity of neuroblastoma cells to AT7519 is partially dependent on MYCN amplification status. Fig. S2. AT7519 more potently induces PARP cleavage in MYCN-amplified neuroblastoma cells. Fig. S3. FACS plots show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423265fb51fd901d839d835c54768647
https://doi.org/10.1158/1078-0432.22454799.v1
https://doi.org/10.1158/1078-0432.22454799.v1
Autor:
Jan J. Molenaar, Louis Chesler, Huib N. Caron, Rogier Versteeg, Robbert J. Kok, Rolf W. Sparidans, Kevin Petrie, Simon P. Robinson, Albert Hallsworth, Yann Jamin, Carel J.M. van Noesel, Ilona J.M. den Hartog, Marli E. Ebus, Evon Poon, M. Emmy M. Dolman
Legends for supplementary figures S1-S8.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164ae6e54525d419e2ea8febad561764
https://doi.org/10.1158/1078-0432.22454811
https://doi.org/10.1158/1078-0432.22454811