Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Keunsook K Lee"'
Autor:
Arnab Pradhan, Carmen Herrero-de-Dios, Rodrigo Belmonte, Susan Budge, Angela Lopez Garcia, Aljona Kolmogorova, Keunsook K Lee, Brennan D Martin, Antonio Ribeiro, Attila Bebes, Raif Yuecel, Neil A R Gow, Carol A Munro, Donna M MacCallum, Janet Quinn, Alistair J P Brown
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006405 (2017)
Most fungal pathogens of humans display robust protective oxidative stress responses that contribute to their pathogenicity. The induction of enzymes that detoxify reactive oxygen species (ROS) is an essential component of these responses. We showed
Externí odkaz:
https://doaj.org/article/0bcccfd3be4c4b918c36e51dafd68ae0
Autor:
Murielle Chauvel, Sophie Bachellier-Bassi, Anne-Marie Guérout, Keunsook K. Lee, Corinne Maufrais, Emmanuelle Permal, Juliana Pipoli Da Fonseca, Sadri Znaidi, Didier Mazel, Carol A. Munro, Christophe d’Enfert, Melanie Legrand
Publikováno v:
Research in Microbiology
Research in Microbiology, 2023, 174 (3), pp.104025. ⟨10.1016/j.resmic.2022.104025⟩
Research in Microbiology, 2023, 174 (3), pp.104025. ⟨10.1016/j.resmic.2022.104025⟩
International audience; Candida albicans is a major fungal pathogen of humans. Although its genome has been sequenced more than two decades ago, there are still over 4300 uncharacterized C. albicans genes. We previously generated an ORFeome as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4f8cdb7829f98dd3d30defb3f7461a
https://hal-pasteur.archives-ouvertes.fr/pasteur-04131602/file/1-s2.0-S0923250822001061-main.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-04131602/file/1-s2.0-S0923250822001061-main.pdf
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Candida albicans is a human opportunist pathogen that can grow as yeast, pseudohyphae, or true hyphae in vitro and in vivo, depending on environmental conditions. Reversible cellular morphogenesis is an important virulence factor that facilitates inv
Externí odkaz:
https://doaj.org/article/76dc6c85bab040c1900ea663c5662cb0
Autor:
Neil A. R. Gow, Filomena Nogueira, Alessandra da Silva Dantas, Megan D. Lenardon, Louise A. Walker, Keunsook K. Lee, Alexandra C. Brand, Matt Edmondson
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Echinocandins such as caspofungin are frontline antifungal drugs that compromise β-1,3 glucan synthesis in the cell wall. Recent reports have shown that fungal cells can resist killing by caspofungin by upregulation of chitin synthesis, thereby sust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cfe37285c62b839c25760eb52391f3
https://doi.org/10.1242/jcs.258889
https://doi.org/10.1242/jcs.258889
Autor:
Keunsook K. Lee, Darin L. Wiesner, Neil A. R. Gow, Jeanette Wagener, Liliane Mukaremera, Kirsten Nielsen
Publikováno v:
The Cell Surface, Vol 1, Iss, Pp 15-24 (2018)
Cryptococcus neoformans is a human fungal pathogen that often causes infections in immunocompromised individuals. Upon inhalation into the lungs C. neoformans differentiates into cells with altered size and morphology, including production of large t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2608f388f0937594793d272f73585bd3
http://www.sciencedirect.com/science/article/pii/S2468233017300634
http://www.sciencedirect.com/science/article/pii/S2468233017300634
Autor:
Nikhat Manzoor, Elvira Román, Pranjali Agarwal, Lasse van Wijlick, Keunsook K. Lee, Jesús Pla, Neil A. R. Gow, Sumit Kumar Rastogi, Joachim F. Ernst, Shivani Ror, Sneh Lata Panwar
Publikováno v:
Cellular Microbiology. 22
Hypoxic adaptation pathways, essential for Candida albicans pathogenesis, are tied to its transition from a commensal to a pathogen. Herein, we identify a WW domain-containing protein, Ifu5, as a determinant of hypoxic adaptation that also impacts no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b546228fc0086bd21e9429a3934ddc
https://doi.org/10.1111/cmi.13140
https://doi.org/10.1111/cmi.13140
Autor:
Aiysha Thompson, James S. Griffiths, Louise Walker, Diogo M. da Fonseca, Keunsook K. Lee, Philip R. Taylor, Neil A. R. Gow, Selinda J. Orr
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Four Candida spp. (albicans, glabrata, tropicalis, parapsilosis) cause >95% of invasive Candida infections. C. albicans elicits immune responses via pathogen recognition receptors including C-type lectin-like receptors (CLRs). The CLR, Dectin-1 is im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::b09d38a6641f90af6322b542b071395e
https://www.frontiersin.org/article/10.3389/fmicb.2019.01800/full
https://www.frontiersin.org/article/10.3389/fmicb.2019.01800/full
Autor:
Louise A. Walker, I. I. Smaczynska-de Rooij, Kathryn R. Ayscough, Keunsook K. Lee, H. C. Knafler, Neil A. R. Gow
Publikováno v:
mBio
mBio, Vol 10, Iss 2, p e02421-18 (2019)
mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e02421-18 (2019)
mBio, Vol 10, Iss 2 (2019)
Candida albicans is a human commensal yeast that can cause significant morbidity and mortality in immunocompromised individuals. Within humans, C. albicans can adopt different morphologies as yeast or filamentous hyphae and can occupy different niche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4728576ea103d0527f81be862e73a1
Autor:
Neil A. R. Gow, David R. Andes, Shabnam Sircaik, Jesús Pla, Sneh Lata Panwar, Elvira Román, Priyanka Bapat, Keunsook K. Lee, Clarissa J. Nobile
Publikováno v:
Cellular microbiology
Cellular microbiology, vol 23, iss 5
Cellular microbiology, vol 23, iss 5
The unfolded protein response (UPR), crucial for the maintenance of endoplasmic reticulum (ER) homeostasis, is tied to the regulation of multiple cellular processes in pathogenic fungi. Here, we show that Candida albicans relies on an ER-resident pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ced7b44555d9f807a5ad80aca0c6b79
http://europepmc.org/articles/PMC8044019
http://europepmc.org/articles/PMC8044019
Autor:
Mélanie, Legrand, Sophie, Bachellier-Bassi, Keunsook K, Lee, Yogesh, Chaudhari, Hélène, Tournu, Laurence, Arbogast, Hélène, Boyer, Murielle, Chauvel, Vitor, Cabral, Corinne, Maufrais, Audrey, Nesseir, Irena, Maslanka, Emmanuelle, Permal, Tristan, Rossignol, Louise A, Walker, Ute, Zeidler, Sadri, Znaidi, Floris, Schoeters, Charlotte, Majgier, Renaud A, Julien, Laurence, Ma, Magali, Tichit, Christiane, Bouchier, Patrick, Van Dijck, Carol A, Munro, Christophe, d'Enfert
Publikováno v:
Nucleic Acids Research
The advent of the genomic era has made elucidating gene function on a large scale a pressing challenge. ORFeome collections, whereby almost all ORFs of a given species are cloned and can be subsequently leveraged in multiple functional genomic approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fffe4ab1c4e4b62f413befaf04d73e3
https://pubmed.ncbi.nlm.nih.gov/29982705
https://pubmed.ncbi.nlm.nih.gov/29982705