Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Keun-Joong Lee"'
Autor:
Gokul Swaminathan, Michael Citron, Jianying Xiao, James E. Norton, Abigail L. Reens, Begüm D. Topçuoğlu, Julia M. Maritz, Keun-Joong Lee, Daniel C. Freed, Teresa M. Weber, Cory H. White, Mahika Kadam, Erin Spofford, Erin Bryant-Hall, Gino Salituro, Sushma Kommineni, Xue Liang, Olga Danilchanka, Jane A. Fontenot, Christopher H. Woelk, Dario A. Gutierrez, Daria J. Hazuda, Geoffrey D. Hannigan
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1340 (2021)
Emerging evidence demonstrates a connection between microbiome composition and suboptimal response to vaccines (vaccine hyporesponse). Harnessing the interaction between microbes and the immune system could provide novel therapeutic strategies for im
Externí odkaz:
https://doaj.org/article/c57141bfb4b545c0b73222a00565d3e1
Autor:
Dmitri A. Pissarnitski, Ahmet Kekec, Lin Yan, Yuping Zhu, Danqing D. Feng, Pei Huo, Christina Madsen-Duggan, Christopher R. Moyes, Ravi P. Nargund, Terri Kelly, Xiaoping Zhang, Ester Carballo-Jane, Judith Gorski, Peter Zafian, Mo Qatanani, Niels Kaarsholm, Fanyu Meng, Xiujuan Jia, Keun-Joong Lee, Weixun Wang, Sherrie Xu, Michael J. Hohn, Michael J. Iammarino, Mark A. McCoy, Grace A. Okoh, Yingkai Liang, Scott A. Hollingsworth, Mark D. Erion, David E. Kelley, Robert M. Garbaccio, Amy Zhang, James Mu, Songnian Lin
Publikováno v:
Journal of Medicinal Chemistry. 65:5593-5605
We have identified a series of novel insulin receptor partial agonists (IRPAs) with a potential to mitigate the risk of hypoglycemia associated with the use of insulin as an antidiabetic treatment. These molecules were designed as dimers of native in
Autor:
Gregory L. Adams, Parul S. Pall, Steven M. Grauer, Xiaoping Zhou, Jeanine E. Ballard, Marissa Vavrek, Richard L. Kraus, Pierre Morissette, Nianyu Li, Stefania Colarusso, Elisabetta Bianchi, Anandan Palani, Rebecca Klein, Christopher T. John, Deping Wang, Matthew Tudor, Andrew F. Nolting, Mirlinda Biba, Timothy Nowak, Alexey A. Makarov, Mikhail Reibarkh, Alexei V. Buevich, Wendy Zhong, Erik L. Regalado, Xiao Wang, Qi Gao, Aurash Shahripour, Yuping Zhu, Daniele de Simone, Tommaso Frattarelli, Nicolo’ Maria Pasquini, Paola Magotti, Roberto Iaccarino, Yuxing Li, Kelli Solly, Keun-Joong Lee, Weixun Wang, Feifei Chen, Haoyu Zeng, Jixin Wang, Hilary Regan, Rupesh P. Amin, Christopher P. Regan, Christopher S. Burgey, Darrell A. Henze, Chengzao Sun, David M. Tellers
Publikováno v:
Journal of Medicinal Chemistry. 65:485-496
Autor:
Xue Liang, Begüm D. Topçuoğlu, Erin Spofford, Julia M. Maritz, Sushma Kommineni, Cory H. White, Olga Danilchanka, Daria J. Hazuda, Geoffrey D. Hannigan, Teresa M. Weber, Michael P. Citron, Jianying Xiao, Christopher H. Woelk, Daniel C. Freed, Erin Bryant-Hall, Keun-Joong Lee, Jane Fontenot, Gokul Swaminathan, Gino Salituro, Dario A. Gutierrez, Mahika Kadam, James E. Norton, Abigail L. Reens
Publikováno v:
Vaccines
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1340, p 1340 (2021)
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1340, p 1340 (2021)
Emerging evidence demonstrates a connection between microbiome composition and suboptimal response to vaccines (vaccine hyporesponse). Harnessing the interaction between microbes and the immune system could provide novel therapeutic strategies for im
Autor:
Pissarnitski, Dmitri A., Kekec, Ahmet, Lin Yan, Yuping Zhu, Feng, Danqing D., Pei Huo, Madsen-Duggan, Christina, Moyes, Christopher R., Nargund, Ravi P., Kelly, Terri, Xiaoping Zhang, Carballo-Jane, Ester, Gorski, Judith, Zafian, Peter, Mo Qatanani, Kaarsholm, Niels, Fanyu Meng, Xiujuan Jia, Keun-Joong Lee, Weixun Wang
Publikováno v:
Journal of Medicinal Chemistry; 4/14/2022, Vol. 65 Issue 7, p5593-5605, 13p
Autor:
Paul Harradine, Lucinda Hittle, Bernard K. Choi, Weixun Wang, Jianzhong Wen, Keun-Joong Lee, Gino Salituro
Publikováno v:
Journal of the American Society for Mass Spectrometry. 30(9)
Peptides represent a promising modality for the design of novel therapeutics that can potentially modulate traditionally non-druggable targets. Cell-penetrating peptides (CPPs) and antimicrobial peptides (AMPs) are two large families that are being e
Autor:
Zack Zhiqiang Guo, Keun-Joong Lee, Gino Salituro, Timothy Rhodes, Christopher W. Boyce, Lina Liu, Dennis Leung, Annette Bak
Publikováno v:
International Journal of Pharmaceutics. 592:120026
A diverse set of drug and polymer combinations have been effectively evaluated utilizing a newly developed method called acoustic fusion to form amorphous solid dispersions (ASD) on the mg-scale, indicating that this approach is a general procedure t
Publikováno v:
AAPS PharmSciTech. 16:1091-1100
The development of drug dispersions using solid lipids is a novel formulation strategy that can help address the challenges of poor drug solubility and systemic exposure after oral administration. The highly lipophilic and poorly water-soluble drug t
Publikováno v:
Chemical research in toxicology. 23(12)
A simple, reliable, and accurate method was developed for quantitative assessment of metabolite coverage in preclinical safety species by mixing equal volumes of human plasma with blank plasma of animal species and vice versa followed by an analysis
Publikováno v:
Handbook of Vanilla Science and Technology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c59c80deca8a622f075a1e5b2e1091
https://doi.org/10.1002/9781444329353.ch11
https://doi.org/10.1002/9781444329353.ch11