Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Keun Sam, Jang"'
Autor:
Sung-Sik Lee, Sungyul Lee, Byung Chul Lee, Gi Hyung Jang, Young Ho Oh, Keun Sam Jang, Sung Wook Park, Dong Woo Kim
Publikováno v:
Bulletin of the Korean Chemical Society. 40:894-897
Publikováno v:
ChemistrySelect. 2:7227-7232
The highly regioselective and efficient synthesis of diverse substituted-benzothiazoles, including heterocyclic units and amino groups, was achieved in moderate to high yields from ortho-bromothiobenzanilides, ortho-bromoarylthioureas, ortho-bromoben
Autor:
Robert A. Koeppe, Yong Woon Jung, Guie Gu, Phillip S. Sherman, Keun Sam Jang, Carole Quesada, David M. Raffel
Publikováno v:
ACS Chemical Neuroscience. 8:1530-1542
Fluorine-18 labeled phenethylguanidines are currently under development in our laboratory as radiotracers for quantifying regional cardiac sympathetic nerve density using PET imaging techniques. In this study, we report an efficient synthesis of 18F-
Publikováno v:
Tetrahedron. 72:5106-5114
Divergent functionalized 8-methoxyquinaldines were synthesized via regioselective debromination, 1,3-bromine shift process, aromatization with treatment of a strong base, nucleophilic substitution reaction at the C7 position using amines and cyanide
Autor:
David M, Raffel, Yong-Woon, Jung, Robert A, Koeppe, Keun Sam, Jang, Guie, Gu, Peter J H, Scott, Venkatesh L, Murthy, Jill, Rothley, Kirk A, Frey
Publikováno v:
Circulation. Cardiovascular imaging. 11(12)
Disease-induced damage to cardiac autonomic nerve populations is associated with an increased risk of sudden cardiac death. The extent of cardiac sympathetic denervation, assessed using planar scintigraphy or positron emission tomography, has been sh
Autor:
Keun Sam Jang, David M. Raffel, Robert A. Koeppe, Venkatesh L. Murthy, Yong-Woon Jung, Kirk A. Frey, Guie Gu, Jill Rothley, Peter Scott
Publikováno v:
Circulation: Cardiovascular Imaging. 11
Background: Disease-induced damage to cardiac autonomic nerve populations is associated with an increased risk of sudden cardiac death. The extent of cardiac sympathetic denervation, assessed using planar scintigraphy or positron emission tomography,
Publikováno v:
Korean Journal of Applied Statistics. 27:543-552
High bandwidth RF such as Bluetooth, GPRS, EDGE, 3GSM, HSDPA is papular in the mobile phone market. A non-conducting metal coating process requires an e-beam deposition of metal, two steps of UV hard coating primer and top coating; however, it is ine
Autor:
Sang Hee Lee, Dong Wook Kim, David M. Raffel, Sang Eun Kim, Sungyul Lee, Byung Chul Lee, Sung-Sik Lee, Keun Sam Jang, Young Ho Oh
Publikováno v:
Journal of Fluorine Chemistry. 227:109387
We analyze the effects of protecting group(s) on the efficiency of aromatic 18F-labeling of guanidine-containing radiopharmaceuticals by quantum chemical methods. We elucidate the origin of experimental observations: The fully protected N,N’,N’
Autor:
Keun Sam Jang, Carole Quesada, David M. Raffel, Yong Woon Jung, Robert A. Koeppe, Guie Gu, Phillip S. Sherman
Publikováno v:
Journal of Nuclear Medicine. 54:1645-1652
UNLABELLED Most cardiac sympathetic nerve radiotracers are substrates of the norepinephrine transporter (NET). Existing tracers such as (123)I-metaiodobenzylguanidine ((123)I-MIBG) and (11)C-(-)-meta-hydroxyephedrine ((11)C-HED) are flow-limited trac
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:1612-1616
A new cardiac sympathetic nerve imaging agent, [(18)F]4-fluoro-m-hydroxyphenethylguanidine ([(18)F]4F-MHPG), was synthesized and evaluated. The radiosynthetic intermediate [(18)F]4-fluoro-m-tyramine ([(18)F]4F-MTA) was prepared and then sequentially