Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ketevan Siradze"'
Autor:
Sivan Cohen, Shan Chung, Christoph Spiess, Victor Lundin, Eric Stefanich, Steven T. Laing, Vanessa Clark, Jochen Brumm, Ying Zhou, Catherine Huang, Joyce Guerrero, Srividya Myneni, Rajbharan Yadav, Ketevan Siradze, Kun Peng
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Bispecific antibodies (bsAbs) recognize and bind two different targets or two epitopes of the same antigen, making them an attractive diagnostic and treatment modality. Compared to the production of conventional bivalent monospecific antibodies, bsAb
Externí odkaz:
https://doaj.org/article/94fdf7b855084e94b55121a2d490ecd9
Publikováno v:
Bioanalysis. 13(4)
Background: Anti-A/B is a bispecific monoclonal antibody that blocks activities of soluble targets A and B. Robust immune responses were observed in a multiple-dose cynomolgus monkey toxicology study, negatively impacting the toxicokinetics/pharmacod
Autor:
Ying Zhou, Jochen Brumm, Steven T Laing, Victor Lundin, Rajbharan Yadav, Joyce Guerrero, Kun Peng, Catherine Huang, Sivan Cohen, Vanessa Clark, Shan Chung, Eric Stefanich, Srividya Myneni, Christoph Spiess, Ketevan Siradze
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Bispecific antibodies (bsAbs) recognize and bind two different targets or two epitopes of the same antigen, making them an attractive diagnostic and treatment modality. Compared to the production of conventional bivalent monospecific antibodies, bsAb
Publikováno v:
The AAPS journal. 21(1)
The interleukin (IL)-17 pathway has been implicated in the pathophysiology of many autoimmune diseases. MCAF5352A is a humanized monoclonal antibody which targets both IL-17A and IL-17F, thereby inhibiting the activity of IL-17 dimers (IL-17AA, IL-17
Autor:
Ketevan Siradze, Patricia O’Connor, Josefina Naya-Vigne, Lin T. Guey, Rita F. Redberg, Clive R. Pullinger, Christian Zellner, Brian Y. Ishida, Prakash Deedwania, John P. Kane, Omar L. Francone, Philip H. Frost, Albert B. Seymour, Mary J. Malloy, Jason M. Laramie
Publikováno v:
The American Journal of Cardiology. 108:360-366
Preβ-1 high-density lipoprotein (HDL) plays a key role in reverse cholesterol transport by promoting cholesterol efflux. Our aims were (1) to test previous associations between preβ-1 HDL and coronary heart disease (CHD) and (2) to investigate whet