Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics.

Autor: Nagler A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Kalaora S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Barbolin C; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Gangaev A; Division of Molecular Oncology and Immunology, the Netherlands Cancer Institute, the Netherlands., Ketelaars SLC; Division of Molecular Oncology and Immunology, the Netherlands Cancer Institute, the Netherlands., Alon M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Pai J; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Benedek G; Tissue Typing and Immunogenetics Unit, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Israel., Yahalom-Ronen Y; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel., Erez N; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel., Greenberg P; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Yagel G; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Peri A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Levin Y; The de Botton Institute for Protein Profiling, The Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel., Satpathy AT; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Bar-Haim E; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel., Paran N; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel., Kvistborg P; Tissue Typing and Immunogenetics Unit, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Israel., Samuels Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. Electronic address: yardena.samuels@weizmann.ac.il.

Publikováno v: Cell reports [Cell Rep] 2021 Jun 29; Vol. 35 (13), pp. 109305. Date of Electronic Publication: 2021 Jun 08.

Identification of bacteria-derived HLA-bound peptides in melanoma.

Autor: Kalaora S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Nagler A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Nejman D; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Alon M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Barbolin C; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Barnea E; Department of Biology, Technion - Israel Institute of Technology, Haifa, Israel., Ketelaars SLC; Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Cheng K; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Vervier K; Wellcome Sanger Institute, Cambridge, UK., Shental N; Department of Mathematics and Computer Science, Open University of Israel, Raanana, Israel., Bussi Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel., Rotkopf R; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Levy R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Benedek G; Tissue Typing and Immunogenetics Unit, Hadassah Medical Center, Jerusalem, Israel., Trabish S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Dadosh T; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel., Levin-Zaidman S; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel., Geller LT; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Wang K; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Greenberg P; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Yagel G; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Peri A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Fuks G; Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel., Bhardwaj N; The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Reuben A; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hermida L; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Johnson SB; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Galloway-Peña JR; Department of Veterinary Pathobiology, Texas A&M University, Houston, TX, USA., Shropshire WC; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, TX, USA., Bernatchez C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Haymaker C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Arora R; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Roitman L; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Eilam R; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Weinberger A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel., Lotan-Pompan M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel., Lotem M; Sharett Institute of Oncology, Hadassah Hebrew University Medical Center, Jerusalem, Israel., Admon A; Department of Biology, Technion - Israel Institute of Technology, Haifa, Israel., Levin Y; The de Botton Institute for Protein Profiling, The Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel., Lawley TD; Wellcome Sanger Institute, Cambridge, UK., Adams DJ; Wellcome Sanger Institute, Cambridge, UK., Levesque MP; Faculty of Medicine, University of Zurich Hospital, University of Zurich, Zurich, Switzerland., Besser MJ; The Ella Lemelbaum Institute for Immuno Oncology and Melanoma, Chaim Sheba Medical Center, Tel Hashomer, Israel.; Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Schachter J; The Ella Lemelbaum Institute for Immuno Oncology and Melanoma, Chaim Sheba Medical Center, Tel Hashomer, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Golani O; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Segal E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel., Geva-Zatorsky N; The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.; MaRS Centre, Canadian Institute for Advanced Research (CIFAR) Azrieli Global Scholar, Toronto, Ontario, Canada., Ruppin E; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Kvistborg P; Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Peterson SN; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Wargo JA; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Straussman R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Samuels Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. yardena.samuels@weizmann.ac.il.

Publikováno v: Nature [Nature] 2021 Apr; Vol. 592 (7852), pp. 138-143. Date of Electronic Publication: 2021 Mar 17.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Autor: Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, Univ. of Modena and Reggio Emilia School of Medicine, Modena, Italy., Chang HD; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Radbruch A; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Acs A; Department of Biology, Nikolaus-Fiebiger-Center for Molecular Medicine, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany., Adam D; Institut für Immunologie, Christian-Albrechts-Universität zu Kiel, Kiel, Germany., Adam-Klages S; Institut für Transfusionsmedizin, Universitätsklinik Schleswig-Holstein, Kiel, Germany., Agace WW; Mucosal Immunology group, Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark.; Immunology Section, Lund University, Lund, Sweden., Aghaeepour N; Departments of Anesthesiology, Pain and Perioperative Medicine, Biomedical Data Sciences; and Pediatrics, Stanford University, Stanford, CA, USA., Akdis M; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland., Allez M; Université de Paris, Institut de Recherche Saint-Louis, INSERM U1160, and Gastroenterology Department, Hôpital Saint-Louis - APHP, Paris, France., Almeida LN; Institute for Systemic Inflammation Research, University of Luebeck, Luebeck, Germany., Alvisi G; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Italy., Anderson G; University of Birmingham, Birmingham, UK., Andrä I; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany., Annunziato F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Anselmo A; Flow Cytometry Core, Humanitas Clinical and Research Center, Milan, Italy., Bacher P; Institut für Immunologie, Christian-Albrechts-Universität zu Kiel, Kiel, Germany.; Institut für Klinische Molekularbiologie, Christian-Albrechts Universität zu Kiel, Germany., Baldari CT; Department of Life Sciences, University of Siena, Siena, Italy., Bari S; Division of Medical Sciences, National Cancer Centre Singapore, Singapore.; Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore., Barnaba V; Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, Italy.; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.; Istituto Pasteur - Fondazione Cenci Bolognetti, Rome, Italy., Barros-Martins J; Institute of Immunology, Hannover Medical School, Hannover, Germany., Battistini L; IRCCS Fondazione Santa Lucia, Rome, Italy., Bauer W; Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, Vienna, Austria., Baumgart S; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Baumgarth N; Center for Comparative Medicine & Dept. Pathology, Microbiology & Immunology, University of California, Davis, CA, USA., Baumjohann D; Institute for Immunology, Faculty of Medicine, Biomedical Center, LMU Munich, Planegg-Martinsried, Germany., Baying B; Genomics Core Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Bebawy M; Discipline of Pharmacy, Graduate School of Health, The University of Technology Sydney, Sydney, NSW, Australia., Becher B; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.; Comprehensive Cancer Center Zurich, Switzerland., Beisker W; Flow Cytometry Laboratory, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München, German Research Center for Environmental Health, München, Germany., Benes V; Genomics Core Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Beyaert R; Department of Biomedical Molecular Biology, Center for Inflammation Research, Ghent University - VIB, Ghent, Belgium., Blanco A; Flow Cytometry Core Technologies, UCD Conway Institute, University College Dublin, Dublin, Ireland., Boardman DA; Department of Surgery, The University of British Columbia, Vancouver, Canada.; BC Children's Hospital Research Institute, Vancouver, Canada., Bogdan C; Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Erlangen, Germany.; Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Medical Immunology Campus Erlangen, Erlangen, Germany., Borger JG; Department of Immunology and Pathology, Monash University, Melbourne, Victoria, Australia., Borsellino G; Neuroimmunology and Flow Cytometry Units, Fondazione Santa Lucia IRCCS, Rome, Italy., Boulais PE; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.; The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Bronx, New York, USA., Bradford JA; Thermo Fisher Scientific, Eugene, Oregon, USA., Brenner D; Luxembourg Institute of Health, Department of Infection and Immunity, Experimental and Molecular Immunology, Esch-sur-Alzette, Luxembourg.; Odense University Hospital, Odense Research Center for Anaphylaxis, University of Southern Denmark, Department of Dermatology and Allergy Center, Odense, Denmark.; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Belvaux, Luxembourg., Brinkman RR; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.; Terry Fox Laboratory, BC Cancer, Vancouver, BC, Canada., Brooks AES; University of Auckland, School of Biological Sciences, Maurice Wilkins Center, Auckland, New Zealand., Busch DH; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany.; Focus Group ''Clinical Cell Processing and Purification', Institute for Advanced Study, Technische Universität München, Munich, Germany., Büscher M; Biophysics, R&D Engineering, Miltenyi Biotec GmbH, Bergisch Gladbach, Germany., Bushnell TP; Department of Pediatrics and Shared Resource Laboratories, University of Rochester Medical Center, Rochester, NY, USA., Calzetti F; University of Verona, Department of Medicine, Section of General Pathology, Verona, Italy., Cameron G; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., Cammarata I; Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, Italy., Cao X; National Key Laboratory of Medical Immunology, Nankai University, Tianjin, China., Cardell SL; Department of Microbiology and Immunology, University of Gothenburg, Gothenburg, Sweden., Casola S; The FIRC Institute of Molecular Oncology (FOM), Milan, Italy., Cassatella MA; University of Verona, Department of Medicine, Section of General Pathology, Verona, Italy., Cavani A; National Institute for Health, Migration and Poverty (INMP), Rome, Italy., Celada A; Macrophage Biology Group, School of Biology, University of Barcelona, Barcelona, Spain., Chatenoud L; Université Paris Descartes, Institut National de la Santé et de la Recherche Médicale, Paris, France., Chattopadhyay PK; Isaac and Laura Perlmutter Cancer Center, NYU-Langone Medical Center, New York, USA., Chow S; Divsion of Medical Oncology and Hematology, Princess Margaret Hospital, Toronto, Ontario, Canada., Christakou E; Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, UK.; National Institutes of Health Research Biomedical Research Centre at Guy's and St. Thomas' National Health Service, Foundation Trust and King's College London, UK., Čičin-Šain L; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany., Clerici M; IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.; Department of Physiopathology and Transplants, University of Milan, Milan, Italy.; Milan Center for Neuroscience, University of Milano-Bicocca, Milan, Italy., Colombo FS; Flow Cytometry Core, Humanitas Clinical and Research Center, Milan, Italy., Cook L; BC Children's Hospital Research Institute, Vancouver, Canada.; Department of Medicine, The University of British Columbia, Vancouver, Canada., Cooke A; Department of Pathology, University of Cambridge, Cambridge, UK., Cooper AM; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Corbett AJ; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., Cosma A; National Cytometry Platform, Luxembourg Institute of Health, Department of Infection and Immunity, Esch-sur-Alzette, Luxembourg., Cosmi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Coulie PG; de Duve Institute, Université catholique de Louvain, Brussels, Belgium., Cumano A; Unit Lymphopoiesis, Department of Immunology, Institut Pasteur, Paris, France., Cvetkovic L; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., Dang VD; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Dang-Heine C; Clinical Research Unit, Berlin Institute of Health (BIH), Charite Universitätsmedizin Berlin, Berlin, Germany., Davey MS; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria, Australia., Davies D; Flow Cytometry Scientific Technology Platform, The Francis Crick Institute, London, UK., De Biasi S; Department of Surgery, Medicine, Dentistry and Morphological Sciences, Univ. of Modena and Reggio Emilia, Modena, Italy., Del Zotto G; IRCCS Istituto Giannina Gaslini, Genova, Italy., Dela Cruz GV; Novo Nordisk Foundation Center for Stem Cell Biology - DanStem, University of Copenhagen, Copenhagen, Denmark., Delacher M; Regensburg Center for Interventional Immunology (RCI), Regensburg, Germany.; Chair for Immunology, University Regensburg, Germany., Della Bella S; Department of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy., Dellabona P; Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy., Deniz G; Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Immunology, Istanbul, Turkey., Dessing M; Sony Europe Ltd, Weybridge, UK., Di Santo JP; Innate Immunty Unit, Department of Immunology, Institut Pasteur, Paris, France.; Institut Pasteur, Inserm U1223, Paris, France., Diefenbach A; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany., Dieli F; University of Palermo, Central Laboratory of Advanced Diagnosis and Biomedical Research, Department of Biomedicine, Neurosciences and Advanced Diagnostics, Palermo, Italy., Dolf A; Flow Cytometry Core Facility, Institute of Experimental Immunology, University of Bonn, Bonn, Germany., Dörner T; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Dept. Medicine/Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Germany., Dress RJ; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore., Dudziak D; Department of Dermatology, Laboratory of Dendritic Cell Biology, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany., Dustin M; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Dutertre CA; Program in Emerging Infectious Disease, Duke-NUS Medical School, Singapore.; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore., Ebner F; Institute of Immunology, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Germany., Eckle SBG; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., Edinger M; Regensburg Center for Interventional Immunology (RCI), Regensburg, Germany.; Department of Internal Medicine III, University Hospital Regensburg, Germany., Eede P; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Germany., Ehrhardt GRA; Department of Immunology, University of Toronto, Toronto, ON, Canada., Eich M; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany., Engel P; University of Barcelona, Faculty of Medicine and Health Sciences, Department of Biomedical Sciences, Barcelona, Spain., Engelhardt B; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Erdei A; Department of Immunology, University L. Eotvos, Budapest, Hungary., Esser C; Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany., Everts B; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands., Evrard M; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore., Falk CS; Institute of Transplant Immunology, Hannover Medical School, MHH, Hannover, Germany., Fehniger TA; Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA., Felipo-Benavent M; Laboratory of Cytomics, Joint Research Unit CIPF-UVEG, Principe Felipe Research Center, Valencia, Spain., Ferry H; Experimental Medicine Division, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Feuerer M; Regensburg Center for Interventional Immunology (RCI), Regensburg, Germany.; Chair for Immunology, University Regensburg, Germany., Filby A; The Flow Cytometry Core Facility, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Filkor K; MDQuest Ltd., Szeged, Hungary., Fillatreau S; Institut Necker-Enfants Malades, Université Paris Descartes Sorbonne Paris Cité, Faculté de Médecine, AP-HP, Hôpital Necker Enfants Malades, INSERM U1151-CNRS UMR 8253, Paris, France., Follo M; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Universitaetsklinikum Freiburg, Lighthouse Core Facility, Zentrum für Translationale Zellforschung, Klinik für Innere Medizin I, Freiburg, Germany., Förster I; Immunology and Environment, LIMES Institute, University of Bonn, Bonn, Germany., Foster J; Owl Biomedical Inc., Santa Barbara, USA., Foulds GA; John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham, UK., Frehse B; Institute for Systemic Inflammation Research, University of Luebeck, Luebeck, Germany., Frenette PS; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.; The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Bronx, New York, USA.; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA., Frischbutter S; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venereology and Allergology., Fritzsche W; Nanobiophotonics Department, Leibniz Institute of Photonic Technology (IPHT), Jena, Germany., Galbraith DW; School of Plant Sciences and Bio5 Institute, University of Arizona, Tucson, USA.; Honorary Dean of Life Sciences, Henan University, Kaifeng, China., Gangaev A; Division of Molecular Oncology and Immunology, the Netherlands Cancer Institute, Amsterdam, The Netherlands., Garbi N; Institute of Experimental Immunology, University of Bonn, Germany., Gaudilliere B; Stanford Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, CA, USA., Gazzinelli RT; Fundação Oswaldo Cruz - Minas, Laboratory of Immunopatology, Belo Horizonte, MG, Brazil.; Department of Mecicine, University of Massachusetts Medical School, Worcester, MA, USA., Geginat J; INGM - Fondazione Istituto Nazionale di Genetica Molecolare 'Ronmeo ed Enrica Invernizzi', Milan, Italy., Gerner W; Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Austria.; Christian Doppler Laboratory for Optimized Prediction of Vaccination Success in Pigs, Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Austria., Gherardin NA; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., Ghoreschi K; Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Gibellini L; Department of Surgery, Medicine, Dentistry and Morphological Sciences, Univ. of Modena and Reggio Emilia, Modena, Italy., Ginhoux F; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore.; Translational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore.; Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Goda K; Department of Bioengineering, University of California, Los Angeles, California, USA.; Department of Chemistry, University of Tokyo, Tokyo, Japan.; Institute of Technological Sciences, Wuhan University, Wuhan, China., Godfrey DI; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., Goettlinger C; Institut für Genetik, Universität zu Köln, Köln, Germany., González-Navajas JM; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain.; Networked Biomedical Research Center for Hepatic and Digestive Diseases (CIBERehd), Madrid, Spain., Goodyear CS; Institute of Infection Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow Biomedical Research Centre, Glasgow, UK., Gori A; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, University of Milan., Grogan JL; Cancer Immunology Research, Genentech, South San Francisco, CA, USA., Grummitt D; Owl Biomedical Inc., Santa Barbara, USA., Grützkau A; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Haftmann C; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Hahn J; Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen., Hammad H; Department of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Zwijnaarde, Belgium., Hämmerling G; German Cancer Research Center (DKFZ), Heidelberg, Germany., Hansmann L; Berlin Institute of Health (BIH), Berlin, Germany.; German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany.; Department of Hematology, Oncology, and Tumor Immunology, Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany., Hansson G; Department of Medicine and Center for Molecular Medicine at Karolinska University Hospital, Solna, Sweden., Harpur CM; Murdoch Children's Research Institute, Parkville, Victoria, Australia., Hartmann S; Institute of Immunology, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Germany., Hauser A; Department of Internal Medicine III, University Hospital Regensburg, Germany., Hauser AE; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin.; Department of Rheumatology and Clinical Immunology, Berlin Institute of Health, Berlin, Germany., Haviland DL; Flow Cytometry, Houston Methodist Hospital Research Institute, Houston, TX, USA., Hedley D; Divsion of Medical Oncology and Hematology, Princess Margaret Hospital, Toronto, Ontario, Canada., Hernández DC; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Medical Department I, Division of Gastroenterology, Infectiology and Rheumatology, Berlin, Germany., Herrera G; Cytometry Service, Incliva Foundation. Clinic Hospital and Faculty of Medicine, University of Valencia, Valencia, Spain., Herrmann M; Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen., Hess C; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland.; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK., Höfer T; German Cancer Research Center (DKFZ), Division of Theoretical Systems Biology, Heidelberg, Germany., Hoffmann P; Regensburg Center for Interventional Immunology (RCI), Regensburg, Germany.; Department of Internal Medicine III, University Hospital Regensburg, Germany., Hogquist K; Center for Immunology, University of Minnesota, Minneapolis, MN, USA., Holland T; Institute of Experimental Immunology, University of Bonn, Germany., Höllt T; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, The Netherlands.; Computer Graphics and Visualization, Department of Intelligent Systems, TU Delft, Delft, The Netherlands., Holmdahl R; Karolinska Institutet Biomedicum, Solna, Sweden., Hombrink P; Department of Experimental Immunology, Amsterdam Infection and Immunity Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Houston JP; Department of Chemical & Materials Engineering, New Mexico State University, Las Cruces, NM, USA., Hoyer BF; Rheumatologie/Klinische Immunologie, Klinik für Innere Medizin I und Exzellenzzentrum Entzündungsmedizin, Universitätsklinikum Schleswig-Holstein, Kiel, Germany., Huang B; Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, China., Huang FP; Institute for Advanced Study (IAS), Shenzhen University, Shenzhen, China., Huber JE; Institute for Immunology, Faculty of Medicine, Biomedical Center, LMU Munich, Planegg-Martinsried, Germany., Huehn J; Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany., Hundemer M; Department of Hematology, Oncology and Rheumatology, University Heidelberg, Heidelberg, Germany., Hunter CA; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hwang WYK; Department of Hematology, Singapore General Hospital, Singapore.; Cancer & Stem Cell Biology, Duke-NUS Medical School, Singapore.; Executive Offices, National Cancer Centre Singapore, Singapore., Iannone A; Department of Diagnostic Medicine, Clinical and Public Health, Univ. of Modena and Reggio Emilia, Modena, Italy., Ingelfinger F; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Ivison SM; Department of Surgery, The University of British Columbia, Vancouver, Canada.; BC Children's Hospital Research Institute, Vancouver, Canada., Jäck HM; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., Jani PK; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Max Planck Institute for Infection Biology, Berlin, Germany., Jávega B; Laboratory of Cytomics, Joint Research Unit CIPF-UVEG, Department of Biochemistry and Molecular Biology, University of Valencia, Valencia, Spain., Jonjic S; Department of Histology and Embryology/Center for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia., Kaiser T; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Kalina T; Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic., Kamradt T; Jena University Hospital, Institute of Immunology, Jena, Germany., Kaufmann SHE; Max Planck Institute for Infection Biology, Berlin, Germany., Keller B; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Ketelaars SLC; Division of Molecular Oncology and Immunology, the Netherlands Cancer Institute, Amsterdam, The Netherlands., Khalilnezhad A; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Khan S; Department of Immunology, University of Toronto, Toronto, ON, Canada., Kisielow J; Institute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland., Klenerman P; Experimental Medicine Division, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Knopf J; Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen., Koay HF; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., Kobow K; Department of Neuropathology, Universitätsklinikum Erlangen, Germany., Kolls JK; John W Deming Endowed Chair in Internal Medicine, Center for Translational Research in Infection and Inflammation Tulane School of Medicine, New Orleans, LA, USA., Kong WT; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore., Kopf M; Institute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland., Korn T; Department of Neurology, Technical University of Munich, Munich, Germany., Kriegsmann K; Department of Hematology, Oncology and Rheumatology, University Heidelberg, Heidelberg, Germany., Kristyanto H; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands., Kroneis T; Division of Cell Biology, Histology & Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Krueger A; Institute for Molecular Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany., Kühne J; Institute of Transplant Immunology, Hannover Medical School, MHH, Hannover, Germany., Kukat C; FACS & Imaging Core Facility, Max Planck Institute for Biology of Ageing, Cologne, Germany., Kunkel D; Flow & Mass Cytometry Core Facility, Charité - Universitätsmedizin Berlin and Berlin Institute of Health, Berlin, Germany.; BCRT Flow Cytometry Lab, Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin., Kunze-Schumacher H; Institute for Molecular Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany., Kurosaki T; WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan., Kurts C; Institute of Experimental Immunology, University of Bonn, Germany., Kvistborg P; Division of Molecular Oncology and Immunology, the Netherlands Cancer Institute, Amsterdam, The Netherlands., Kwok I; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore., Landry J; Genomics Core Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Lantz O; INSERM U932, PSL University, Institut Curie, Paris, France., Lanuti P; Department of Medicine and Aging Sciences, Centre on Aging Sciences and Translational Medicine (Ce.S.I.-Me.T.), University 'G. d'Annunzio' of Chieti-Pescara, Chieti, Italy., LaRosa F; IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.; Milan Center for Neuroscience, University of Milano-Bicocca, Milan, Italy., Lehuen A; Institut Cochin, CNRS8104, INSERM1016, Department of Endocrinology, Metabolism and Diabetes, Université de Paris, Paris, France., LeibundGut-Landmann S; Section of Immunology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland., Leipold MD; The Human Immune Monitoring Center (HIMC), Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, CA, USA., Leung LYT; Department of Immunology, University of Toronto, Toronto, ON, Canada., Levings MK; Department of Surgery, The University of British Columbia, Vancouver, Canada.; BC Children's Hospital Research Institute, Vancouver, Canada.; School of Biomedical Engineering, The University of British Columbia, Vancouver, Canada., Lino AC; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Dept. Medicine/Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Germany., Liotta F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Litwin V; Caprion Biosciences, ImmuneCarta, Montréal, Quebec, Canada., Liu Y; Department of Immunology, University of Toronto, Toronto, ON, Canada., Ljunggren HG; Center for Infectious Medicine, Department of Medicine Huddinge, ANA Futura, Karolinska Institutet, Stockholm, Sweden., Lohoff M; Inst. f. Med. Mikrobiology and Hospital Hygiene, University of Marburg, Germany., Lombardi G; King's College London, 'Peter Gorer' Department of Immunobiology, London, UK., Lopez L; Beckman Coulter, Inc, Miami, FL, USA., López-Botet M; IMIM(Hospital de Mar Medical Research Institute), University Pompeu Fabra, Barcelona, Spain., Lovett-Racke AE; Department of Microbial Infection and Immunity, Ohio State University, Columbus, OH, USA., Lubberts E; Department of Rheumatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Luche H; Centre d'Immunophénomique - CIPHE (PHENOMIN), Aix Marseille Université (UMS3367), Inserm (US012), CNRS (UMS3367), Marseille, France., Ludewig B; Institute of Immunobiology, Kantonsspital St.Gallen, St. Gallen, Switzerland., Lugli E; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Italy.; Flow Cytometry Core, Humanitas Clinical and Research Center, Milan, Italy., Lunemann S; Department of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany., Maecker HT; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA., Maggi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Maguire O; Flow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Mair F; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA., Mair KH; Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Austria.; Christian Doppler Laboratory for Optimized Prediction of Vaccination Success in Pigs, Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Austria., Mantovani A; Istituto Clinico Humanitas IRCCS and Humanitas University, Pieve Emanuele, Milan, Italy.; William Harvey Research Institute, Queen Mary University, London, United Kingdom., Manz RA; Institute for Systemic Inflammation Research, University of Luebeck, Luebeck, Germany., Marshall AJ; Department of Immunology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada., Martínez-Romero A; Cytomics Technological Service, Principe Felipe Research Center, Valencia, Spain., Martrus G; Department of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany., Marventano I; IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.; Milan Center for Neuroscience, University of Milano-Bicocca, Milan, Italy., Maslinski W; National Institute of Geriatrics, Rheumatology and Rehabilitation, Department of Pathophysiology and Immunology, Warsaw, Poland., Matarese G; Treg Cell Lab, Dipartimento di Medicina Molecolare e Biotecologie Mediche, Università di Napoli Federico II and Istituto per l'Endocrinologia e l'Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Napoli, Italy., Mattioli AV; Department of Surgery, Medicine, Dentistry and Morphological Sciences, Univ. of Modena and Reggio Emilia, Modena, Italy.; Lab of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy., Maueröder C; Cell Clearance in Health and Disease Lab, VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Mazzoni A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., McCluskey J; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., McGrath M; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., McGuire HM; Ramaciotti Facility for Human Systems Biology, and Discipline of Pathology, The University of Sydney, Camperdown, Australia., McInnes IB; Institute of Infection Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow Biomedical Research Centre, Glasgow, UK., Mei HE; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Melchers F; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Max Planck Institute for Infection Biology, Berlin, Germany., Melzer S; Clinical Trial Center Leipzig, University Leipzig, Leipzig, Germany., Mielenz D; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., Miller SD; Interdepartmental Immunobiology Center, Dept. of Microbiology-Immunology, Northwestern Univ. Medical School, Chicago, IL, USA., Mills KHG; Trinity College Dublin, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Dublin, Ireland., Minderman H; Flow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Mjösberg J; Center for Infectious Medicine, Department of Medicine Huddinge, ANA Futura, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical and Experimental Medine, Linköping University, Linköping, Sweden., Moore J; Abramson Cancer Center Flow Cytometry and Cell Sorting Shared Resource, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Moran B; Trinity College Dublin, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Dublin, Ireland., Moretta L; Department of Immunology, IRCCS Bambino Gesu Children's Hospital, Rome, Italy., Mosmann TR; David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY, USA., Müller S; Centre for Environmental Research - UFZ, Department Environmental Microbiology, Leipzig, Germany., Multhoff G; Institute for Innovative Radiotherapy (iRT), Experimental Immune Biology, Helmholtz Zentrum München, Neuherberg, Germany.; Radiation Immuno-Oncology Group, Center for Translational Cancer Research Technische Universität München (TranslaTUM), Klinikum rechts der Isar, Munich, Germany., Muñoz LE; Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen., Münz C; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.; Comprehensive Cancer Center Zurich, Switzerland., Nakayama T; Department of Immunology, Graduate School of Medicine, Chiba University, Chiba city, Chiba, Japan., Nasi M; Department of Surgery, Medicine, Dentistry and Morphological Sciences, Univ. of Modena and Reggio Emilia, Modena, Italy., Neumann K; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ng LG; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore.; Discipline of Dermatology, University of Sydney, Sydney, New South Wales, Australia.; State Key Laboratory of Experimental Hematology, Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China., Niedobitek A; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Nourshargh S; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK., Núñez G; Department of Pathology and Rogel Cancer Center, the University of Michigan, Ann Arbor, Michigan, USA., O'Connor JE; Laboratory of Cytomics, Joint Research Unit CIPF-UVEG, Department of Biochemistry and Molecular Biology, University of Valencia, Valencia, Spain., Ochel A; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Oja A; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Ordonez D; Flow Cytometry Core Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Orfao A; Department of Medicine, Cancer Research Centre (IBMCC-CSIC/USAL), Cytometry Service, University of Salamanca, CIBERONC and Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Orlowski-Oliver E; Burnet Institute, AMREP Flow Cytometry Core Facility, Melbourne, Victoria, Australia., Ouyang W; Inflammation and Oncology, Research, Amgen Inc, South San Francisco, USA., Oxenius A; ETH Zurich, Institute of Microbiology, Zurich, Switzerland., Palankar R; Department of Transfusion Medicine, Institute of Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany., Panse I; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Pattanapanyasat K; Center of Excellence for Flow Cytometry, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Paulsen M; Flow Cytometry Core Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Pavlinic D; Genomics Core Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Penter L; Department of Hematology, Oncology, and Tumor Immunology, Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany., Peterson P; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Peth C; Biophysics, R&D Engineering, Miltenyi Biotec GmbH, Bergisch Gladbach, Germany., Petriz J; Functional Cytomics Group, Josep Carreras Leukaemia Research Institute, Campus ICO-Germans Trias i Pujol, Universitat Autònoma de Barcelona, UAB, Badalona, Spain., Piancone F; IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.; Milan Center for Neuroscience, University of Milano-Bicocca, Milan, Italy., Pickl WF; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Piconese S; Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, Italy.; Istituto Pasteur - Fondazione Cenci Bolognetti, Rome, Italy., Pinti M; Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Pockley AG; John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham, UK.; Chromocyte Limited, Electric Works, Sheffield, UK., Podolska MJ; Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen.; Department for Internal Medicine 3, Institute for Rheumatology and Immunology, AG Munoz, Universitätsklinikum Erlangen, Erlangen, Germany., Poon Z; Department of Hematology, Singapore General Hospital, Singapore., Pracht K; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., Prinz I; Institute of Immunology, Hannover Medical School, Hannover, Germany., Pucillo CEM; Department of Immunology, University of Udine, Udine, Italy., Quataert SA; David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY, USA., Quatrini L; Department of Immunology, IRCCS Bambino Gesu Children's Hospital, Rome, Italy., Quinn KM; School of Biomedical and Health Sciences, RMIT University, Bundoora, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia., Radbruch H; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Germany., Radstake TRDJ; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Rahmig S; Regeneration in Hematopoiesis, Leibniz-Institute on Aging, Fritz-Lipmann-Institute (FLI), Jena, Germany., Rahn HP; Preparative Flow Cytometry, Max-Delbrück-Centrum für Molekulare Medizin, Berlin, Germany., Rajwa B; Bindley Biosciences Center, Purdue University, West Lafayette, IN, USA., Ravichandran G; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Raz Y; Department of Internal Medicine, Groene Hart Hospital, Gouda, The Netherlands., Rebhahn JA; David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY, USA., Recktenwald D; Desatoya LLC, Reno, NV, USA., Reimer D; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., Reis e Sousa C; Immunobiology Laboratory, The Francis Crick Institute, London, UK., Remmerswaal EBM; Department of Experimental Immunology, Amsterdam Infection and Immunity Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Renal Transplant Unit, Division of Internal Medicine, Academic Medical Centre, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Richter L; Core Facility Flow Cytometry, Biomedical Center, Ludwig-Maximilians-University Munich, Germany., Rico LG; Functional Cytomics Group, Josep Carreras Leukaemia Research Institute, Campus ICO-Germans Trias i Pujol, Universitat Autònoma de Barcelona, UAB, Badalona, Spain., Riddell A; Flow Cytometry Scientific Technology Platform, The Francis Crick Institute, London, UK., Rieger AM; Department of Medical Microbiology and Immunology, University of Alberta, Alberta, Canada., Robinson JP; Purdue University Cytometry Laboratories, Purdue University, West Lafayette, IN, USA., Romagnani C; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Medical Department I, Division of Gastroenterology, Infectiology and Rheumatology, Berlin, Germany., Rubartelli A; Cell Biology Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Ruland J; Institut für Klinische Chemie und Pathobiochemie, Fakultät für Medizin, Technische Universität München, München, Germany., Saalmüller A; Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Austria., Saeys Y; Data Mining and Modeling for Biomedicine, VIB-UGent Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium., Saito T; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Sakaguchi S; WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan., Sala-de-Oyanguren F; Flow Cytometry Facility, Ludwig Cancer Institute, Faculty of Medicine and Biology, University of Lausanne, Epalinges, Switzerland., Samstag Y; Heidelberg University, Institute of Immunology, Section of Molecular Immunology, Heidelberg, Germany., Sanderson S; Translational Immunology Laboratory, NIHR BRC, University of Oxford, Kennedy Institute of Rheumatology, Oxford, UK., Sandrock I; Institute of Immunology, Hannover Medical School, Hannover, Germany., Santoni A; Department of Molecular Medicine, Sapienza University of Rome, IRCCS, Neuromed, Pozzilli, Italy., Sanz RB; Institute of Transplant Immunology, Hannover Medical School, MHH, Hannover, Germany., Saresella M; IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.; Milan Center for Neuroscience, University of Milano-Bicocca, Milan, Italy., Sautes-Fridman C; Centre de Recherches des Cordeliers, Equipe Cancer et Immunité anti-tumorale, Paris, France., Sawitzki B; Charité - Universitätsmedizin Berlin, and Berlin Institute of Health, Institute of Medical Immunology, Berlin, Germany., Schadt L; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.; Comprehensive Cancer Center Zurich, Switzerland., Scheffold A; Institut für Immunologie, Christian-Albrechts-Universität zu Kiel, Kiel, Germany., Scherer HU; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands., Schiemann M; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany., Schildberg FA; Clinic for Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany., Schimisky E; R&D Reagents, Miltenyi Biotec GmbH, Bergisch Gladbach, Germany., Schlitzer A; Quantitative Systems Biology, Life & Medical Sciences Institute, University of Bonn, Bonn, Germany., Schlosser J; Institute of Immunology, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Germany., Schmid S; Internal Medicine I, University Hospital Regensburg, Germany., Schmitt S; Flow Cytometry Core Facility, German Cancer Research Centre (DKFZ), Heidelberg, Germany., Schober K; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany., Schraivogel D; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Schuh W; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., Schüler T; Institute of Molecular and Clinical Immunology, Otto-von-Guericke University, Magdeburg, Germany., Schulte R; University of Cambridge, Cambridge Institute for Medical Research, Cambridge, UK., Schulz AR; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany., Schulz SR; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., Scottá C; King's College London, 'Peter Gorer' Department of Immunobiology, London, UK., Scott-Algara D; Institut Pasteur, Cellular Lymphocytes Biology, Immunology Departement, Paris, France., Sester DP; TRI Flow Cytometry Suite (TRI.fcs), Translational Research Institute, Wooloongabba, QLD, Australia., Shankey TV; AsedaSciences, West Lafayette, IN, USA., Silva-Santos B; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Portugal., Simon AK; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Sitnik KM; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany., Sozzani S; Dept. Molecular Translational Medicine, University of Brescia, Brescia, Italy., Speiser DE; Department of Oncology, University of Lausanne and CHUV, Epalinges, Switzerland., Spidlen J; BD Life Sciences, Ashland, OR, USA., Stahlberg A; Lundberg Laboratory for Cancer, Department of Pathology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Stall AM; BD Life Sciences, San Diego, CA, USA., Stanley N; Departments of Anesthesiology, Pain and Perioperative Medicine, Biomedical Data Sciences; and Pediatrics, Stanford University, Stanford, CA, USA., Stark R; Department of Experimental Immunology, Amsterdam Infection and Immunity Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Stehle C; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Medical Department I, Division of Gastroenterology, Infectiology and Rheumatology, Berlin, Germany., Steinmetz T; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., Stockinger H; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Takahama Y; National Institutes of Health, Bethesda, MD, USA., Takeda K; WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan., Tan L; Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tárnok A; Departement for Therapy Validation, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.; Department of Precision Instruments, Tsinghua University, Beijing, China., Tiegs G; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Toldi G; MDQuest Ltd., Szeged, Hungary., Tornack J; Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.; BioGenes GmbH, Berlin, Germany., Traggiai E; Novartis Biologics Center, Mechanistic Immunology Unit, Novartis Institute for Biomedical Research, NIBR, Basel, Switzerland., Trebak M; Department of Cellular and Molecular Physiology, Penn State University College of Medicine, PA, United States., Tree TIM; Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, UK.; National Institutes of Health Research Biomedical Research Centre at Guy's and St. Thomas' National Health Service, Foundation Trust and King's College London, UK., Trotter J; BD Life Sciences, San Diego, CA, USA., Trowsdale J; Department of Pathology, University of Cambridge, Cambridge, UK., Tsoumakidou M; Institute of Bioinnovation, BSRC Alexander Fleming, Vari, Greece., Ulrich H; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP, Brazil., Urbanczyk S; Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Dept. of Internal Medicine III, University of Erlangen-Nuremberg, Erlangen, Germany., van de Veen W; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.; Christine Kühne Center for Allergy Research and Education (CK-CARE), Davos, Switzerland., van den Broek M; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.; Comprehensive Cancer Center Zurich, Switzerland., van der Pol E; Vesicle Observation Center, Biomedical Engineering & Physics, Laboratory Experimental Clinical Chemistry, Amsterdam University Medical Centers, Location AMC, The Netherlands., Van Gassen S; Data Mining and Modeling for Biomedicine, VIB-UGent Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium., Van Isterdael G; VIB Flow Core, VIB Center for Inflammation Research, Ghent, Belgium., van Lier RAW; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Veldhoen M; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Portugal., Vento-Asturias S; Institute of Experimental Immunology, University of Bonn, Germany., Vieira P; Unit Lymphopoiesis, Department of Immunology, Institut Pasteur, Paris, France., Voehringer D; Department of Infection Biology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany., Volk HD; BIH Center for Regenerative Therapies (BCRT) Charité Universitätsmedizin Berlin and Berlin Institute of Health, Core Unit ImmunoCheck., von Borstel A; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; 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Publikováno v: European journal of immunology [Eur J Immunol] 2019 Oct; Vol. 49 (10), pp. 1457-1973.

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

Autor: Voorwerk L; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Slagter M; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Horlings HM; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Sikorska K; Department of Biometrics, The Netherlands Cancer Institute, Amsterdam, the Netherlands., van de Vijver KK; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Pathology, Ghent University Hospital, Ghent, Belgium., de Maaker M; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Nederlof I; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Kluin RJC; Genomics Core Facility, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Warren S; NanoString Technologies, Inc., Seattle, WA, USA., Ong S; NanoString Technologies, Inc., Seattle, WA, USA., Wiersma TG; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Russell NS; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Lalezari F; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Schouten PC; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Bakker NAM; Oncode Institute, Utrecht, the Netherlands.; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Ketelaars SLC; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Peters D; Core Facility Molecular Pathology & Biobanking, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Lange CAH; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., van Werkhoven E; Department of Biometrics, The Netherlands Cancer Institute, Amsterdam, the Netherlands., van Tinteren H; Department of Biometrics, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Mandjes IAM; Department of Biometrics, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Kemper I; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Onderwater S; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Chalabi M; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Wilgenhof S; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Haanen JBAG; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Salgado R; Department of Pathology, GZA-ZNA Ziekenhuizen, Antwerp, Belgium.; Division of Research, Peter Mac Callum Cancer Center, Melbourne, Victoria, Australia., de Visser KE; Oncode Institute, Utrecht, the Netherlands.; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Sonke GS; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Wessels LFA; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Linn SC; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Schumacher TN; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Blank CU; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Kok M; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. m.kok@nki.nl.; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. m.kok@nki.nl.

Publikováno v: Nature medicine [Nat Med] 2019 Jun; Vol. 25 (6), pp. 920-928. Date of Electronic Publication: 2019 May 13.