Interferon-Tau Exerts Direct Prosurvival and Antiapoptotic Actions in Luteinized Bovine Granulosa Cells

Autor: Raghavendra Basavaraja, Senasige Thilina Madusanka, Jessica N. Drum, Ketan Shrestha, Svetlana Farberov, Milo C. Wiltbank, Roberto Sartori, Rina Meidan

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model f

Externí odkaz: https://doaj.org/article/3326da401a86496fb5e8ca0ccc2b3ac7

Neurotensin: a neuropeptide induced by hCG in the human and rat ovary during the periovulatory period

Autor: Diane M. Duffy, Linah Al-Alem, James W. Akin, Mats Brännström, Thomas E. Curry, Ketan Shrestha, Kathy Rosewell, Misung Jo, Muraly Puttabyatappa, Yohan Choi

Publikováno v: Biol Reprod

Neurotensin (NTS) is a tridecapeptide that was first characterized as a neurotransmitter in neuronal cells. The present study examined ovarian NTS expression across the periovulatory period in the human and the rat. Women were recruited into this stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3025f37cfc7ff24662faba11721a3829
https://doi.org/10.1093/biolre/ioab036

The cAMP pathway promotes sirtuin-1 expression in human granulosa-lutein cells

Autor: Ketan Shrestha, Avi Harlev, Rina Meidan, Eliezer Girsh, Magdalena Szymanska, Sarah Manthe

Publikováno v: Reproductive Biology. 20:273-281

Sirtuin-1 (SIRT1), a NAD+-dependent deacetylase, is present in the ovarian granulosa cells (GCs) of various species. This study examined the regulation of SIRT1 expression in human granulosa-lutein cells (hGLCs). Two different, structurally unrelated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba58c84c9e837291a7444de6dfe0710
https://doi.org/10.1016/j.repbio.2020.07.010

Sirtuin-1 inhibits endothelin-2 expression in human granulosa-lutein cells via hypoxia inducible factor 1 alpha and epigenetic modifications†

Autor: Ketan Shrestha, Avi Harlev, Tatiana Kisliouk, Sarah Manthe, Rina Meidan, Eliezer Girsh, Magdalena Szymanska

Publikováno v: Biology of reproduction. 104(2)

Endothelin-2 (EDN2) expression in granulosa cells was previously shown to be highly dependent on the hypoxic mediator, hypoxia inducible factor 1 alpha (HIF1A). Here, we investigated whether sirtuin-1 (SIRT1), by deacetylating HIF1A and class III his

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d0a2d63bc8796e3527518daef1cb53
https://pubmed.ncbi.nlm.nih.gov/33112382

Contributors

Autor: Eli Y. Adashi, Azza M. Akasha, Meshach Asare-Werehene, Nelly Auersperg, David H. Barad, T.M. Barber, Rawad Bassil, Shawn M. Briley, John J. Bromfield, Lauren E. Carter, Robert F. Casper, Cindy Chan, Hsun-Ming Chang, Zi-Jiang Chen, David P. Cook, John S. Davis, Rabindranath De La Fuente, K.R. Dunning, Ofer Fainaru, Heng-Yu Fan, J.K. Findlay, W.G. Foster, S. Franks, H.C. Furlong, Daniela Galliano, A.M. Gannon, R.B. Gilchrist, Norbert Gleicher, Jigal Haas, Jing Hang, Camilla K. Hughes, Ilpo Huhtaniemi, Katja Hummitzsch, K.J. Hutt, Helen F. Irving-Rodgers, H.J. Kimbel, Shahar Kol, Vitaly A. Kushnir, Holly A. LaVoie, Yi-Xuan Lee, Richard S. Legro, Peter C.K. Leung, Chi-Kwan Leung, Mo Li, Pei-Hsuan Lin, Gang Lu, Yue Lv, Yun-Yi Ma, Kelly E. Mayo, Rina Meidan, Gordon B. Mills, E.E. Nilsson, Kutluk Oktay, Stephanie A. Pangas, Joy L. Pate, Nuria Pellicer, Antonio Pellicer, Rachel L. Piersanti, Roger A. Pierson, Rexxi D. Prasasya, Rebecca A. Previs, Jie Qiao, Yingying Qin, Endah Rahmawati, Adolfo Rivero-Müller, Rebecca L. Robker, Raymond J. Rodgers, Daniela Rodler, Amanda Rodriguez, Darryl L. Russell, Robert T. Rydze, Alan Schneyer, Jeff Schwartz, David B. Seifer, Dar-Bin Shieh, Ketan Shrestha, Joe Leigh Simpson, Fred Sinowatz, M.K. Skinner, Yong Sang Song, Jerome F. Strauss, Qing-Yuan Sun, Yu Sun, Reshef Tal, Enes Taylan, Benjamin K. Tsang, Chii-Ruey Tzeng, Barbara C. Vanderhyden, Maria M. Viveiros, Ian N. Waldman, K.A. Walters, Yun Wang, Corrine Welt, Shannon N. Westin, Teresa K. Woodruff, Jie Yan, Han Zhao, Xu Zhi, Yi-Min Zhu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9a21c32c31954a0a7a8a65c23865160
https://doi.org/10.1016/b978-0-12-813209-8.09992-1