Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ketaki, Ganti"'
Autor:
Ketaki Ganti, Anish Bagga, Silvia Carnaccini, Lucas M. Ferreri, Ginger Geiger, C. Joaquin Caceres, Brittany Seibert, Yonghai Li, Liping Wang, Taeyong Kwon, Yuhao Li, Igor Morozov, Wenjun Ma, Juergen A. Richt, Daniel R. Perez, Katia Koelle, Anice C. Lowen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Virus reassortment drives genetic diversity and evolution and is governed by intra-host dynamics that are less well understood. Here, the authors characterise the within-host dynamics of influenza A virus reassortment in swine, ferrets and guinea pig
Externí odkaz:
https://doaj.org/article/2a977b93d93f4addbfde5d614e81fd52
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1010978 (2023)
When multiple viral populations propagate within the same host environment, they often shape each other's dynamics. These interactions can be positive or negative and can occur at multiple scales, from coinfection of a cell to co-circulation at a glo
Externí odkaz:
https://doaj.org/article/96a86c668c624f1eb0503fd04c49b203
Autor:
Ketaki Ganti, Lucas M Ferreri, Chung-Young Lee, Camden R Bair, Gabrielle K Delima, Kate E Holmes, Mehul S Suthar, Anice C Lowen
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010181 (2022)
Transmission efficiency is a critical factor determining the size of an outbreak of infectious disease. Indeed, the propensity of SARS-CoV-2 to transmit among humans precipitated and continues to sustain the COVID-19 pandemic. Nevertheless, the numbe
Externí odkaz:
https://doaj.org/article/87806f9fdb7a401f87e01272785b6fef
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009321 (2021)
Influenza A virus [IAV] genomes comprise eight negative strand RNAs packaged into virions in the form of viral ribonucleoproteins [vRNPs]. Rab11a plays a crucial role in the transport of vRNPs from the nucleus to the plasma membrane via microtubules,
Externí odkaz:
https://doaj.org/article/94c024f6533d41b39114d70db168e97c
Autor:
Julianna Han, Ketaki Ganti, Veeresh Kumar Sali, Carly Twigg, Yifeng Zhang, Senthamizharasi Manivasagam, Chieh-Yu Liang, Olivia A Vogel, Iris Huang, Shanan N Emmanuel, Jesse Plung, Lillianna Radoshevich, Jasmine T Perez, Anice C Lowen, Balaji Manicassamy
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009517 (2021)
It is well documented that influenza A viruses selectively package 8 distinct viral ribonucleoprotein complexes (vRNPs) into each virion; however, the role of host factors in genome assembly is not completely understood. To evaluate the significance
Externí odkaz:
https://doaj.org/article/90b1301d28c24690ba02d23585dab79c
Autor:
Brenda M Calderon, Shamika Danzy, Gabrielle K Delima, Nathan T Jacobs, Ketaki Ganti, Megan R Hockman, Graeme L Conn, Anice C Lowen, John Steel
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007892 (2019)
The M segment of the 2009 pandemic influenza A virus (IAV) has been implicated in its emergence into human populations. To elucidate the genetic contributions of the M segment to host adaptation, and the underlying mechanisms, we examined a panel of
Externí odkaz:
https://doaj.org/article/8d1b51a008484550be7fee121c465810
Autor:
Ketaki Ganti, Anish Bagga, Juliana DaSilva, Samuel S. Shepard, John R. Barnes, Susan Shriner, Katia Koelle, Anice C. Lowen
Publikováno v:
Viruses, Vol 13, Iss 3, p 509 (2021)
Reassortment among co-infecting influenza A viruses (IAVs) is an important source of viral diversity and can facilitate expansion into novel host species. Indeed, reassortment played a key role in the evolution of the last three pandemic IAVs. Observ
Externí odkaz:
https://doaj.org/article/69024973ab5749baadbf7a73967fbae9
Autor:
Ketaki Ganti, Justyna Broniarczyk, Wiem Manoubi, Paola Massimi, Suruchi Mittal, David Pim, Anita Szalmas, Jayashree Thatte, Miranda Thomas, Vjekoslav Tomaić, Lawrence Banks
Publikováno v:
Viruses, Vol 7, Iss 7, Pp 3530-3551 (2015)
Cancer-causing HPV E6 oncoproteins are characterized by the presence of a PDZ binding motif (PBM) at their extreme carboxy terminus. It was long thought that this region of E6 had a sole function to confer interaction with a defined set of cellular s
Externí odkaz:
https://doaj.org/article/028d97401366449fb303d6059bd08eff
Autor:
Ketaki Ganti, Paola Massimi, Joaquin Manzo-Merino, Vjekoslav Tomaić, David Pim, Martin P Playford, Marcela Lizano, Sally Roberts, Christian Kranjec, John Doorbar, Lawrence Banks
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005854 (2016)
A subset of high-risk Human Papillomaviruses (HPVs) are the causative agents of a large number of human cancers, of which cervical is the most common. Two viral oncoproteins, E6 and E7, contribute directly towards the development and maintenance of m
Externí odkaz:
https://doaj.org/article/18b738b8e2334f26835e0e89c7a86bf5
Autor:
Gene S. Tan, Silvia Carnaccini, Maria C. White, Anice C. Lowen, Lucas M. Ferreri, Ketaki Ganti, Brett E. Pickett, Kara L. Phipps, Miglena Manandhar, Daniel R. Perez, Chung-Young Lee, Nathan T. Jacobs
Publikováno v:
Nature microbiology
Infection with a single influenza A virus (IAV) is only rarely sufficient to initiate productive infection. Here, we exploit both single-cell approaches and whole-animal systems to show that IAV reliance on multiple infection can form an important sp