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pro vyhledávání: '"Ket Yin Goh"'
Autor:
Ajeena Ramanujan, Lik-Wei Wong, Carlos F. Ibáñez, Ket Yin Goh, Sreedharan Sajikumar, Kazuhiro Tanaka, Chenju Yi
Publikováno v:
EMBO J
A prevalent model of Alzheimer’s disease (AD) pathogenesis postulates the generation of neurotoxic fragments derived from the amyloid precursor protein (APP) after its internalization to endocytic compartments. The molecular pathways that regulate
Autor:
Kazuhiro Tanaka, Chenju Yi, Carlos F. Ibáñez, Sajikumar Sreedharan, Lik-Wei Wong, Ket Yin Goh
A prevalent model of Alzheimer’s disease (AD) pathogenesis postulates the generation of neurotoxic fragments derived from the amyloid precursor protein (APP) after its internalization to endocytic compartments. However, the molecular pathways that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715feda426019205d814757e06b2e5bc
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(20)
The p75 neurotrophin receptor (p75NTR) mediates neuronal death in response to neural insults by activating a caspase apoptotic pathway. The oligomeric state and activation mechanism that enable p75NTRto mediate these effects have recently been called