Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

Autor: Khan, Aly A., Lugade, Amit, Lazic, Ana M. Mijalkovic, Frentzen, Angela A. Elizabeth, Tadmor, Arbel D., Sasson, Ariella S., Rao, Arjun A., Pei, Baikang, Schrörs, Barbara, Berent-Maoz, Beata, Carreno, Beatriz M., Song, Bin, Peters, Bjoern, Li, Bo, Higgs, Brandon W., Stevenson, Brian J., Iseli, Christian, Miller, Christopher A., Morehouse, Christopher A., Melief, Cornelis J.M., Puig-Saus, Cristina, van Beek, Daphne, Balli, David, Gfeller, David, Haussler, David, Jäger, Dirk, Cortes, Eduardo, Esaulova, Ekaterina, Sherafat, Elham, Arcila, Francisco, Bartha, Gabor, Liu, Geng, Coukos, George, Richard, Guilhem, Chang, Han, Si, Han, Zörnig, Inka, Xenarios, Ioannis, Mandoiu, Ion, Kooi, Irsan, Conway, James P., Kessler, Jan H., Greenbaum, Jason A., Perera, Jason F., Harris, Jason, Hundal, Jasreet, Shelton, Jennifer M., Wang, Jianmin, Wang, Jiaqian, Greshock, Joel, Blake, Jonathon, Szustakowski, Joseph, Kodysh, Julia, Forman, Juliet, Wei, Lei, Lee, Leo J., Fanchi, Lorenzo F., Slagter, Maarten, Lang, Maren, Mueller, Markus, Lower, Martin, Vormehr, Mathias, Artyomov, Maxim N., Kuziora, Michael, Princiotta, Michael, Bassani-Sternberg, Michal, Macabali, Mignonette, Kojicic, Milica R., Yang, Naibo, Raicevic, Nevena M. Ilic, Guex, Nicolas, Robine, Nicolas, Halama, Niels, Skundric, Nikola M., Milicevic, Ognjen S., Gellert, Pascal, Jongeneel, Patrick, Charoentong, Pornpimol, Srivastava, Pramod K., Tanden, Prateek, Shah, Priyanka, Hu, Qiang, Gupta, Ravi, Chen, Richard, Petit, Robert, Ziman, Robert, Hilker, Rolf, Shukla, Sachet A., Al Seesi, Sahar, Boyle, Sean M., Qiu, Si, Sarkizova, Siranush, Salama, Sofie, Liu, Song, Wu, Song, Sridhar, Sriram, Ketelaars, Steven L.C., Jhunjhunwala, Suchit, Shcheglova, Tatiana, Schuepbach, Thierry, Creasy, Todd H., Josipovic, Veliborka, Kovacevic, Vladimir B., Fu, Weixuan, Krebber, Willem-Jan, Hsu, Yi-Hsiang, Sebastian, Yinong, Yalcin, Zeynep Kosaloglu, Huang, Zhiqin, Wells, Daniel K., van Buuren, Marit M., Dang, Kristen K., Hubbard-Lucey, Vanessa M., Sheehan, Kathleen C.F., Campbell, Katie M., Lamb, Andrew, Ward, Jeffrey P., Sidney, John, Blazquez, Ana B., Rech, Andrew J., Zaretsky, Jesse M., Comin-Anduix, Begonya, Ng, Alphonsus H.C., Chour, William, Yu, Thomas V., Rizvi, Hira, Chen, Jia M., Manning, Patrice, Steiner, Gabriela M., Doan, Xengie C., Merghoub, Taha, Guinney, Justin, Kolom, Adam, Selinsky, Cheryl, Ribas, Antoni, Hellmann, Matthew D., Hacohen, Nir, Sette, Alessandro, Heath, James R., Bhardwaj, Nina, Ramsdell, Fred, Schreiber, Robert D., Schumacher, Ton N., Kvistborg, Pia, Defranoux, Nadine A.

Publikováno v: In Cell 29 October 2020 183(3):818-834

Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides

Autor: Kessler, Jan H, Mommaas, Bregje, Mutis, Tuna, Huijbers, Ivo, Vissers, Debby, Benckhuijsen, Willemien E, Schreuder, Geziena M.Th, Offringa, Rienk, Goulmy, Els, Melief, Cornelis J.M, van der Burg, Sjoerd H, Drijfhout, Jan W

Publikováno v: In Human Immunology 2003 64(2):245-255

Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes.

Autor: Kessler, Jan H¹, Khan, Selina¹, Seifert, Ulrike², Le Gall, Sylvie³, Chow, K Martin⁴, Paschen, Annette⁵, Bres-Vloemans, Sandra A¹, de Ru, Arnoud¹, van Montfoort, Nadine¹, Franken, Kees L M C¹, Benckhuijsen, Willemien E¹, Brooks, Jill M⁶, van Hall, Thorbald⁷, Ray, Kallol⁴, Mulder, Arend¹, Doxiadis, Ilias I N¹, van Swieten, Paul F⁸, Overkleeft, Hermen S⁸, Prat, Annik⁹, Tomkinson, Birgitta¹⁰

Publikováno v: Nature Immunology. Jan2011, Vol. 12 Issue 1, p45-53. 9p.

A BCR-ABL Oncoprotein p210b2a2 Fusion Region Sequence Is Recognized by HLA-DR2a Restricted Cytotoxic T Lymphocytes and Presented by HLA-DR Matched Cells Transfected With an Iib2a2 Construct

Autor: ten Bosch, George J.A., Kessler, Jan H., Joosten, Antonia M., Bres-Vloemans, Alexandra A., Geluk, Annemieke, Godthelp, Barbara C., van Bergen, Jeroen, Melief, Cornelis J.M., Leeksma, Onno C.

Publikováno v: In Blood 1 August 1999 94(3):1038-1045

Competition-based cellular peptide binding assay for HLA class I

Autor: Kessler, Jan H., Benckhuijsen, Willemien E., Mutis, Tuna, Melief, C. J., van der Burg, Sjoerd H., Drijfhout, Jan W.

Publikováno v: Kessler, J H, Benckhuijsen, W E, Mutis, T, Melief, C J, van der Burg, S H & Drijfhout, J W 2004, ' Competition-based cellular peptide binding assay for HLA class I. ', Current protocols in immunology / edited by John E. Coligan ... [et al.], vol. Chapter 18 .

This unit describes a competition assay to determine binding of unlabeled test peptides to thirteen of the most prevalent HLA class I molecules. It uses cells expressing the HLA class I molecule of interest on their surface, fluorescently labeled ref

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https://research.vumc.nl/en/publications/a4c03360-d575-4615-ac8a-042471c69fe9