Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Kessler, BM"'
Autor:
Cao, Y, Lin, Y, Sun, N, Du, X, Dong, Y, Mei, S, Deng, X, Li, X, Guo, S, Tang, K, Liu, J, Qiao, X, Zhao, D, Qin, Y, Zhang, C, Xin, T, Shi, X, Zhou, C, Dong, T, Guo, D-A, Kessler, BM, Xu, D, Song, J, Huang, F, Wang, X, Jiang, C
Cross-kingdom herbal miRNA was first reported in 2012. Using a modified herbal extraction protocol, we obtained 73,677,287 sequences by RNA-seq from 245 traditional Chinese Medicine (TCM), of which 20,758,257 were unique sequences. We constructed a B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::52249c12f6e02310b111f0b213135ddb
https://doi.org/10.1007/s11427-022-2181-6
https://doi.org/10.1007/s11427-022-2181-6
Autor:
Olie, CS, Pinto-Fernández, A, Damianou, A, Vendrell, I, Mei, H, den Hamer, B, van der Wal, E, de Greef, JC, Raz, V, Kessler, BM
The ubiquitin proteasomal system is a critical regulator of muscle physiology, and impaired UPS is key in many muscle pathologies. Yet, little is known about the function of deubiquitinating enzymes (DUBs) in the muscle cell context. We performed a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c02ef69f371b2b7a5e84721f23af27
https://doi.org/10.21203/rs.3.rs-2172567/v1
https://doi.org/10.21203/rs.3.rs-2172567/v1
Autor:
O'Brien, DP, Jones, HBL, Guenther, F, Murphy, EJ, England, KS, Anderson, M, Brennan, P, Davis, JB, Pinto-Fernandez, A, Turnbull, AP, Kessler, BM
Dampening functional levels of the mitochondrial deubiquitylating enzyme USP30 has been suggested as an effective therapeutic strategy against neurodegenerative disorders such as Parkinson’s Disease. USP30 inhibition may counteract the deleterious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495729c5e8fd550458d894e15bee01b8
https://doi.org/10.1101/2022.09.13.507798
https://doi.org/10.1101/2022.09.13.507798
Autor:
Kessler, BM
Publikováno v:
Cellular Immunology. 382:104638
Major histocompatibility complex (MHC-I) peptide antigen processing and presentation has experienced a revived interest in the context of immuno oncology, immune surveillance escape by pathogen mutations and technical advances that accelerate vaccine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed96f9042293bb33bef0edeb8400a27
https://doi.org/10.1016/j.cellimm.2022.104638
https://doi.org/10.1016/j.cellimm.2022.104638
Publikováno v:
Biomolecules. 12:300
Ubiquitylation and ISGylation are protein post-translational modifications (PTMs) and two of the main events involved in the activation of pattern recognition receptor (PRRs) signals allowing the host defense response to viruses. As with similar viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9fb77177974fbefc148174dcfa529d
https://doi.org/10.3390/biom12020300
https://doi.org/10.3390/biom12020300
Autor:
Frleta D, Ochoa CE, Kramer HB, Khan SA, Stacey AR, Borrow P, Kessler BM, Haynes BF, Bhardwaj N
Publikováno v:
Retrovirology, Vol 9, Iss Suppl 2, p P183 (2012)
Externí odkaz:
https://doaj.org/article/fe5e402e91684dd2a222e18ba476f91a
Autor:
Jailani, NM, Sani, AA, Fischer, R, Huang, H, Aizat, WM, Nathan, S, Kramer, HB, Kessler, BM, Mackeen, MM
Using Saccharomyces cerevisiae lysate, two in-solution trypsin digestions (chloroform-methanol-water precipitation and RapiGest) were compared to the recently reported gel-aided sample preparation (GASP) workflow. Our proteomic results showed that GA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c2b99d30fdfdc102fbd0bac9d9e406c3
https://doi.org/10.21161/mjm.1461817
https://doi.org/10.21161/mjm.1461817
Supporting Information 1. Raw results obtained from quantitative label-free proteomics analysis of decellularized and enriched tissues of the mouse intact liver (control) and MC38 mouse liver metastasis (tumor).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::443c7809f064ba52cef207e39776134b
https://doi.org/10.17504/protocols.io.7u2hnye
https://doi.org/10.17504/protocols.io.7u2hnye
BACKGROUND: Matrix metalloproteinase 9 (MMP9) has been implicated in extracellular matrix (ECM) remodelling, angiogenesis and inflammation. However, the targets for proteolysis that lead to these physiological consequences are often undefined as is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4ac656bd6f421ba25b87aab59924f462
https://doi.org/10.1002/pros.22690
https://doi.org/10.1002/pros.22690
Microbial pathogens exploit the ubiquitin system to facilitate infection and manipulate the immune responses of the host. In this study, susceptibility to Yersinia enterocolitica and Yersinia pseudotuberculosis invasion was found to be increased upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2c6e10fdfd168fc50e25adeb4d474664
https://ora.ox.ac.uk/objects/uuid:ad871c32-56fd-4d00-98ea-5b0beece9794
https://ora.ox.ac.uk/objects/uuid:ad871c32-56fd-4d00-98ea-5b0beece9794