Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Kesingland A"'
Publikováno v:
In Pain 2003 105(1):355-362
Autor:
Walker, Katharine, Medhurst, Stephen J., Kidd, Bruce L., Glatt, Markus, Bowes, Mick, Patel, Sadhana, McNair, Kara, Kesingland, Adam, Green, Jonathan, Chan, Otto, Fox, Alyson J., Urban, Laszlo A.
Publikováno v:
In Pain 2002 100(3):219-229
Autor:
Fox, Alyson *, Kesingland, Adam, Gentry, Clive, McNair, Kara, Patel, Sadhana, Urban, Laszlo, James, Iain
Publikováno v:
In Pain 2001 92(1):91-100
Autor:
Patel, Sadhana, Naeem, Sami, Kesingland, Adam, Froestl, Wolfgang, Capogna, Marco, Urban, Laszlo, Fox, Alyson *
Publikováno v:
In Pain 2001 90(3):217-226
Autor:
Kesingland, A.C, Gentry, C.T, Panesar, M.S, Bowes, M.A, Vernier, J.-M, Cube, R, Walker, K, Urban, L *
Publikováno v:
In Pain 2000 86(1):113-118
Publikováno v:
Pain. 105:355-362
Anti-epileptic drugs (AEDs) are increasingly used for the treatment of neuropathic pain. Oxcarbazepine is a recently introduced AED that is effective in treating epilepsy and has an improved side-effect profile compared to existing therapies. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116440ea3d0fc48fb6095c8e9c9c6eb9
https://doi.org/10.1016/s0304-3959(03)00253-7
https://doi.org/10.1016/s0304-3959(03)00253-7
Autor:
Kara McNair, Adam Kesingland, Iain F. James, Clive Gentry, Sadhana Patel, Laszlo Urban, Alyson Fox
Publikováno v:
Pain. 92:91-100
We have examined the effects of cannabinoid agonists on hyperalgesia in a model of neuropathic pain in the rat and investigated the possible sites of action. The antihyperalgesic activity of the cannabinoids was compared with their ability to elicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b75c2cf0209c7f0f8ca43de9aa937ea
https://doi.org/10.1016/s0304-3959(00)00474-7
https://doi.org/10.1016/s0304-3959(00)00474-7
Autor:
Adam Kesingland, Natacha Stoehr, Katharine Walker, Adriana Pagano, Will P.J.M Spooren, Fabrizio Gasparini, Clive Gentry, Andrew J. Davis, Kurt Lingenhoehl, Mark A. Varney, Rainer Kuhn, Ivo Vranesic, Edwin C. Johnson, Moh Panesar, Laszlo Urban, M Bowes, Peter J. Flor
Publikováno v:
Neuropharmacology. 40:1-9
The excitatory neurotransmitter, glutamate, is particularly important in the transmission of pain information in the nervous system through the activation of ionotropic and metabotropic glutamate receptors. A potent, subtype-selective antagonist of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c0a7b7a54d1466c16ee4315b2bb8843
https://doi.org/10.1016/s0028-3908(00)00113-1
https://doi.org/10.1016/s0028-3908(00)00113-1
Autor:
Hart Terance William, Kara McNair, Isabelle Lyothier, Christopher Thomas Brain, Marcus Peacock, Paul R. Coote, and Mohammed Yaqoob, Iain F. James, Luigi La Vecchia, Adam Kesingland, Jiri Zadrobilek, Edward K. Dziadulewicz, Ulrich Schopfer, Werner Huber, Andrew James Culshaw, Adrian J. Fisher, Lee Edwards, Alyson Fox, Portmann Robert, † Cathal O'Farrell, Alex Groarke, Stuart Bevan, Andrew J. Davis, Clive Gentry, Yvonne Loong
Publikováno v:
Journal of medicinal chemistry. 50(16)
Selective activation of peripheral cannabinoid CB1 receptors has the potential to become a valuable therapy for chronic pain conditions as long as central nervous system effects are attenuated. A new class of cannabinoid ligands was rationally design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777c052cf3636a39c24a8d1a192898f2
https://pubmed.ncbi.nlm.nih.gov/17630726
https://pubmed.ncbi.nlm.nih.gov/17630726
Autor:
Katharine Walker, Markus Glatt, Sadhana Patel, Stephen J. Medhurst, Mick Bowes, Otto Chan, Bruce L. Kidd, Kara McNair, Adam Kesingland, Laszlo Urban, Alyson Fox, Jonathan Green
Publikováno v:
PainReferences. 100(3)
Inoculation of syngeneic MRMT-1 mammary tumour cells into one tibia of female rats produced tumour growth within the bone associated with a reduction in bone mineral density (BMD) and bone mineral content (BMC), severe radiological signs of bone dest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b3e671d1dce42d30ac6a701dc11b12
https://pubmed.ncbi.nlm.nih.gov/12467993
https://pubmed.ncbi.nlm.nih.gov/12467993